2024
Group cohesion and alliance predict cognitive-behavioral group treatment outcomes for youth with anxiety disorders
Fjermestad K, Wallin M, Naujokat F, McLeod B, Silverman W, Öst L, Lerner M, Heiervang E, Wergeland G. Group cohesion and alliance predict cognitive-behavioral group treatment outcomes for youth with anxiety disorders. Cognitive Behaviour Therapy 2024, ahead-of-print: 1-19. PMID: 39105346, DOI: 10.1080/16506073.2024.2385906.Peer-Reviewed Original ResearchGroup cognitive behavioral therapyAnxiety disordersAnxiety symptomsDiagnostic recoveryParent-reported anxiety symptomsGroup cohesionCognitive behavioral therapyRandomized controlled effectiveness trialBehavioral therapyAlliance changeParent-reported outcomesEffectiveness trialClinical severityTreatment outcomesAnxietyPost-treatmentDisordersAllianceSymptomsYouthFollow-upGeneralized estimating equationsSeveritySessionsOutcomesAnxiety Symptom Trajectories Predict Depression Symptom Trajectories up to Four Years After CBT for Youth Anxiety Disorders
Fjermestad K, Norum F, Brask H, Kodal A, Silverman W, Heiervang E, Wergeland G. Anxiety Symptom Trajectories Predict Depression Symptom Trajectories up to Four Years After CBT for Youth Anxiety Disorders. Research On Child And Adolescent Psychopathology 2024, 52: 1503-1513. PMID: 38878114, PMCID: PMC11461661, DOI: 10.1007/s10802-024-01214-9.Peer-Reviewed Original ResearchCognitive behavioral therapyYouth anxiety disordersAnxiety symptom trajectoriesDepressive symptom trajectoriesDepressive symptomsSymptom trajectoriesParental mental healthAnxiety disordersAnxiety diagnosesMental healthDepression trajectoriesPost-cognitive behavioral therapyAssociated with less depressive symptomsSelf-reported depression levelsAnxiety symptom improvementDepression levelsParent-reported anxietyExamined depressive symptomsLess depressive symptomsGrowth curve modelsSelf-reported mental healthAssessment periodBehavioral therapyAnxiety trajectoriesDiagnostic recoveryPatterns of sub‐optimal change following CBT for childhood anxiety
Bertie L, Arendt K, Coleman J, Cooper P, Creswell C, Eley T, Hartman C, Heiervang E, In‐Albon T, Krause K, Lester K, Marin C, Nauta M, Rapee R, Schneider S, Schniering C, Silverman W, Thastum M, Thirlwall K, Waite P, Wergeland G, Hudson J. Patterns of sub‐optimal change following CBT for childhood anxiety. Journal Of Child Psychology And Psychiatry 2024, 65: 1612-1623. PMID: 38817012, PMCID: PMC11563922, DOI: 10.1111/jcpp.14009.Peer-Reviewed Original ResearchCognitive behavioral therapyAnxiety disordersAnxiety diagnosesGrowth curve modelsMinimal respondersGroup cognitive behavioral therapyPatterns of symptom changeCurve modelClinically anxious youthSocial anxiety disorderAssociated with significantly less improvementResponse patternsAssess patterns of changeAnxious youthDisorder remissionChildhood anxietyMaternal psychopathologyBehavioral therapyDisorder severityDiagnostic statusSymptom changePre-and post-treatmentDelayed respondersAnxietyParental factorsThe Effectiveness of Modular Transdiagnostic Cognitive Behavioral Therapy Versus Treatment as Usual for Youths Displaying School Attendance Problems: A Randomized Controlled Trial
Johnsen D, Lomholt J, Heyne D, Jensen M, Jeppesen P, Silverman W, Thastum M. The Effectiveness of Modular Transdiagnostic Cognitive Behavioral Therapy Versus Treatment as Usual for Youths Displaying School Attendance Problems: A Randomized Controlled Trial. Research On Child And Adolescent Psychopathology 2024, 52: 1397-1412. PMID: 38739306, PMCID: PMC11420258, DOI: 10.1007/s10802-024-01196-8.Peer-Reviewed Original ResearchCognitive behavioral therapyTransdiagnostic cognitive behavioral therapySchool attendance problemsRandomized controlled trialsSelf-efficacyMonths of cognitive behavioral therapyMental healthYouth self-efficacyParental self-efficacyEvidence-based interventionsWithin-group improvementsBehavioral therapyHours of interventionSchool refusalSchool attendanceAssociated with negative short-Emotional problemsConduct problemsSchool involvementIntervention servicesIntervention effectsEffective interventionsControlled trialsAged 6Youth
2023
Does Cognitive-Behavioral Therapy for Youth Anxiety Disorders Improve Social Functioning and Peer Relationships?
Etkin R, Juel E, Lebowitz E, Silverman W. Does Cognitive-Behavioral Therapy for Youth Anxiety Disorders Improve Social Functioning and Peer Relationships? Clinical Child And Family Psychology Review 2023, 26: 1052-1076. PMID: 37838627, DOI: 10.1007/s10567-023-00454-3.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsCognitive behavioral therapyAdolescent anxiety disordersPeer relationshipsSocial functioningAnxiety disordersYouth anxiety disordersPeer outcomesAnxiety reductionTreatment-specific effectsFunctioningTreatment specificitySystematic narrative reviewRelated difficultiesSample characteristicsMajority of studiesSpecific outcomesChildrenTreatment outcomesStatistical findingsStudy sampleDisordersNarrative reviewFindingsRelationshipAnxiety384. Cognitive Behavioral Therapy Normalizes Fronto-Parietal Activation in Unmedicated Patients With Pediatric Anxiety Disorders
Haller S, Linke J, Grassie H, Jones E, Pagliaccio D, Harrewijn A, White L, Naim R, Mallidi A, Berman E, Lewis K, Kircanski K, Silverman W, Kalin N, Bar-Haim Y, Brotman M. 384. Cognitive Behavioral Therapy Normalizes Fronto-Parietal Activation in Unmedicated Patients With Pediatric Anxiety Disorders. Biological Psychiatry 2023, 93: s249. DOI: 10.1016/j.biopsych.2023.02.624.Peer-Reviewed Original Research
2021
Directional effects of parent and child anxiety 1 year following treatment of child anxiety, and the mediational role of parent psychological control
Silverman WK, Marin CE, Rey Y, Jaccard J, Pettit JW. Directional effects of parent and child anxiety 1 year following treatment of child anxiety, and the mediational role of parent psychological control. Depression And Anxiety 2021, 38: 1289-1297. PMID: 34464490, PMCID: PMC8664994, DOI: 10.1002/da.23210.Peer-Reviewed Original ResearchConceptsParents’ psychological controlPsychological controlChild anxietyCognitive behavioral therapyParent anxietyIndividual cognitive behavioral therapyChild's ageAnxiety 1 yearTreatment targetsMediational roleEvidence of childrenBehavioral therapyRecent efficacy trialsParent involvementAnxietyPosttreatmentDirectional effectsParentsClinical implicationsCBT armEvidence of parentChildrenTreatment effectsModeratorEfficacy trialsDoes Training Parents in Reinforcement Skills or Relationship Skills Enhance Individual Youths’ Cognitive Behavioral Therapy for Anxiety? Outcome, Specificity, and Mediation
Silverman WK, Rey Y, Marin CE, Jaccard J, Pettit JW. Does Training Parents in Reinforcement Skills or Relationship Skills Enhance Individual Youths’ Cognitive Behavioral Therapy for Anxiety? Outcome, Specificity, and Mediation. Clinical Psychological Science 2021, 10: 355-373. PMID: 35599840, PMCID: PMC9122107, DOI: 10.1177/21677026211016402.Peer-Reviewed Original ResearchCognitive behavioral therapyNegative reinforcementAnxiety reductionLower anxietyRelationship skillsYouth cognitive behavioral therapiesParental psychological controlBehavioral parenting skillsPrimary anxiety diagnosisReinforcement skillsPsychological controlIndividual CBTTraining parentsParenting skillsBehavioral therapyAnxiety diagnosesPartial mediationCBTParent involvementAnxietyTreatment specificitySkillsYouthFuture researchTreatment studiesModerators of response to child‐based and parent‐based child anxiety treatment: a machine learning‐based analysis
Lebowitz ER, Zilcha‐Mano S, Orbach M, Shimshoni Y, Silverman WK. Moderators of response to child‐based and parent‐based child anxiety treatment: a machine learning‐based analysis. Journal Of Child Psychology And Psychiatry 2021, 62: 1175-1182. PMID: 33624848, DOI: 10.1111/jcpp.13386.Peer-Reviewed Original ResearchConceptsModerators of responseParent negativityChild anxiety treatmentOxytocin levelsBaseline anxietyCognitive behavioral therapyPrimary anxiety disorderChild-reported outcomesParent-reported outcomesChildhood anxietyAnxiety treatmentAnxiety symptomsPotential moderatorsAnxiety disordersTreatment conditionsModeratorMachine learning-based analysisAnxietyNegativitySignificant interactionChildrenNonoptimal treatmentTreatment efficacyParentingSocioemotional
2020
Separating From the Mothership: A Coordinated Individual and Parent-Based Approach to Severe Agoraphobia in a Young Adult
Raila HE, Julian M, Lebowitz ER, Silverman WK. Separating From the Mothership: A Coordinated Individual and Parent-Based Approach to Severe Agoraphobia in a Young Adult. Cognitive And Behavioral Practice 2020, 28: 422-434. PMID: 34305384, PMCID: PMC8296594, DOI: 10.1016/j.cbpra.2020.06.004.Peer-Reviewed Original ResearchCognitive behavioral therapyTraditional cognitive behavioral therapyIntegration of CBTAnxious Childhood EmotionsParent-based treatmentSelf-reported scoresChildhood EmotionsFamily accommodationSupportive parentingPsychological treatmentAdolescent psychopathologyBehavioral indicesAge-appropriate independenceSuch psychopathologyOlder adolescentsSevere agoraphobiaAdult childrenPanic disorderAnxietyYoung adultsPsychopathologyParentsSame treatment centerAgoraphobiaAdultsParent-Child Agreement on Family Accommodation Differentially Predicts Outcomes of Child-Based and Parent-Based Child Anxiety Treatment
Zilcha-Mano S, Shimshoni Y, Silverman WK, Lebowitz ER. Parent-Child Agreement on Family Accommodation Differentially Predicts Outcomes of Child-Based and Parent-Based Child Anxiety Treatment. Journal Of Clinical Child & Adolescent Psychology 2020, 50: 427-439. PMID: 32401557, PMCID: PMC8496486, DOI: 10.1080/15374416.2020.1756300.Peer-Reviewed Original ResearchConceptsParent-child agreementFamily accommodationMultilevel response-surface analysisAnxious Childhood EmotionsChild anxiety treatmentChild anxiety severityCognitive behavioral therapyAnxiety symptom severityDistinct underlying mechanismsChildhood EmotionsChildhood anxietySupportive parentingAnxiety treatmentParent reportBehavioral therapyRole of accommodationAnxiety severityAnxiety disordersPoor treatment outcomesTreatment outcomesSymptom severitySubsequent treatment outcomesTreatment endSignificant predictorsChildren
2019
Latino and Non-Latino Parental Treatment Preferences for Child and Adolescent Anxiety Disorders
Seligman LD, Hovey JD, Ibarra M, Hurtado G, Marin CE, Silverman WK. Latino and Non-Latino Parental Treatment Preferences for Child and Adolescent Anxiety Disorders. Child Psychiatry & Human Development 2019, 51: 617-624. PMID: 31807934, DOI: 10.1007/s10578-019-00945-x.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyLatino parentsChild anxietyNon-Latino white parentsAdolescent anxiety disordersParental involvementParental treatment preferencesPerception of burdenMental health treatmentNon-Latino parentsPotential treatment barriersYouth anxietyBehavioral therapyAnxiety disordersChild's treatmentParent involvementTreatment involvementAnxietyHealth treatmentWhite parentsTreatment barriersParents' preferencesGreater preferenceParentsCurrent studyEfficacy and mechanisms underlying a gamified attention bias modification training in anxious youth: protocol for a randomized controlled trial
Linke JO, Jones E, Pagliaccio D, Swetlitz C, Lewis KM, Silverman WK, Bar-Haim Y, Pine DS, Brotman MA. Efficacy and mechanisms underlying a gamified attention bias modification training in anxious youth: protocol for a randomized controlled trial. BMC Psychiatry 2019, 19: 246. PMID: 31391027, PMCID: PMC6686536, DOI: 10.1186/s12888-019-2224-2.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyContext of CBTBias modification trainingDot-probe taskAttentional biasAnxious youthAmygdala connectivityAnxiety disordersAttention bias modification trainingPrimary anxiety disorder diagnosisHealthy comparison youthAnxiety disorder diagnosisVisual searchThreat responsesNeurobiological correlatesComparison youthBehavioral therapyTraining elementsDisorder diagnosisEngaging gameNeuronal levelYouthPrevious findingsMixed resultsTaskA genome-wide association meta-analysis of prognostic outcomes following cognitive behavioural therapy in individuals with anxiety and depressive disorders
Rayner C, Coleman JRI, Purves KL, Hodsoll J, Goldsmith K, Alpers GW, Andersson E, Arolt V, Boberg J, Bögels S, Creswell C, Cooper P, Curtis C, Deckert J, Domschke K, El Alaoui S, Fehm L, Fydrich T, Gerlach AL, Grocholewski A, Hahlweg K, Hamm A, Hedman E, Heiervang ER, Hudson JL, Jöhren P, Keers R, Kircher T, Lang T, Lavebratt C, Lee SH, Lester KJ, Lindefors N, Margraf J, Nauta M, Pané-Farré CA, Pauli P, Rapee RM, Reif A, Rief W, Roberts S, Schalling M, Schneider S, Silverman WK, Ströhle A, Teismann T, Thastum M, Wannemüller A, Weber H, Wittchen HU, Wolf C, Rück C, Breen G, Eley TC. A genome-wide association meta-analysis of prognostic outcomes following cognitive behavioural therapy in individuals with anxiety and depressive disorders. Translational Psychiatry 2019, 9: 150. PMID: 31123309, PMCID: PMC6533285, DOI: 10.1038/s41398-019-0481-y.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyBehavioral therapyAnxiety disordersTherapy outcomeEvidence-based treatmentsPolygenic scoringMajor depressive disorderGenome-wide association studiesDepressive disorderGenome-wide associationStrong genetic correlationCommon genetic variantsComplex traitsSingle nucleotide polymorphismsWide associationStrongest predictorPsychopathologyAnxietyPersonalityGenetic overlapAssociation studiesGenetic correlationsGenetic variantsNucleotide polymorphismsDisordersGroup- Versus Parent-Involvement CBT for Childhood Anxiety Disorders: Treatment Specificity and Long-Term Recovery Mediation
Silverman WK, Marin CE, Rey Y, Kurtines WM, Jaccard J, Pettit JW. Group- Versus Parent-Involvement CBT for Childhood Anxiety Disorders: Treatment Specificity and Long-Term Recovery Mediation. Clinical Psychological Science 2019, 7: 840-855. PMID: 33758679, PMCID: PMC7984418, DOI: 10.1177/2167702619830404.Peer-Reviewed Original ResearchGroup cognitive behavioral therapyParental psychological controlPsychological controlAnxiety reductionAnxiety disordersYouth anxiety disordersChildhood anxiety disordersPrimary anxiety diagnosisCognitive behavioral therapyTreatment specificityYouth anxietyCBT targetsBehavioral therapyAnxiety diagnosesCBTMediationPutative mediatorsPosttreatmentDisordersAnxietyYouthEfficacy trialsMediatorsParentsSpecific mechanismsA Randomized Controlled Trial of Attention Bias Modification Treatment in Youth With Treatment-Resistant Anxiety Disorders
Pettit JW, Bechor M, Rey Y, Vasey MW, Abend R, Pine DS, Bar-Haim Y, Jaccard J, Silverman WK. A Randomized Controlled Trial of Attention Bias Modification Treatment in Youth With Treatment-Resistant Anxiety Disorders. Journal Of The American Academy Of Child & Adolescent Psychiatry 2019, 59: 157-165. PMID: 30877049, PMCID: PMC6744353, DOI: 10.1016/j.jaac.2019.02.018.Peer-Reviewed Original ResearchConceptsAttention Bias Modification TreatmentAttention control trainingTreatment-resistant anxiety disordersAttention controlAnxiety severityAttention biasNeutral facesAnxiety disordersAttention bias modification trainingBias modification trainingYouth anxiety severityCognitive behavioral therapyAttention trainingDiagnostic recoveryAnxiety diagnosesControl trainingTraining trialsContingency scheduleYouthModification treatmentIndependent evaluatorsAnxietyTrainingAugmentation strategiesFaceParent-Based Treatment as Efficacious as Cognitive-Behavioral Therapy for Childhood Anxiety: A Randomized Noninferiority Study of Supportive Parenting for Anxious Childhood Emotions
Lebowitz ER, Marin C, Martino A, Shimshoni Y, Silverman WK. Parent-Based Treatment as Efficacious as Cognitive-Behavioral Therapy for Childhood Anxiety: A Randomized Noninferiority Study of Supportive Parenting for Anxious Childhood Emotions. Journal Of The American Academy Of Child & Adolescent Psychiatry 2019, 59: 362-372. PMID: 30851397, PMCID: PMC6732048, DOI: 10.1016/j.jaac.2019.02.014.Peer-Reviewed Original ResearchConceptsParent-based treatmentAnxious Childhood EmotionsChildhood anxiety disordersFamily accommodationChildhood anxietyAnxiety disordersChildhood EmotionsSupportive parentingParenting stressAnxiety outcomesCognitive behavioral therapyPrimary anxiety disorderParent interventionBehavioral therapyChildren's ratingsAnxiety severityTreatment credibilityClinician-rated scalesParent treatmentParent involvementAnxietyDiagnostic InterviewEmotionsParentingIndependent evaluatorsTrajectories and Predictors of Response in Youth Anxiety CBT: Integrative Data Analysis
Skriner LC, Chu BC, Kaplan M, Bodden DHM, Bögels SM, Kendall PC, Nauta MH, Silverman WK, Wood JJ, Barker DH, de la Torre J, Saavedra L, Xie MG. Trajectories and Predictors of Response in Youth Anxiety CBT: Integrative Data Analysis. Journal Of Consulting And Clinical Psychology 2019, 87: 198-211. PMID: 30570308, DOI: 10.1037/ccp0000367.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyGrowth mixture modelingIntegrative data analysisParent-reported anxiety symptomsFamily cognitive-behavioral therapySymptom changeTrajectory classesYouth-reported symptomsParent-reported symptomsMixture modelingPredictors of trajectoriesItem response theory modelsAnxious youthImprovement classesAnxiety symptomsRapid respondersResponse classesYouthTheory modelPredictorsDistinct patternsOlder agePredictors of responseMembershipSymptoms
2018
Anxiety Disorders
van Schalkwyk G, Silverman W. Anxiety Disorders. 2018, 298-308. DOI: 10.1093/oxfordhb/9780190634841.013.20.Peer-Reviewed Original ResearchAnxiety disordersAbstract Anxiety disordersAssociated with significant impairmentCognitive behavioral therapyEvidence-based treatmentsBehavioral therapyModification trainingSignificant impairmentAssessment measuresDisordersEvidence baseAccurate differential diagnosisAnxietyGroup of disordersAdolescentsImpairmentTreatmentChildrenParentsInterventionDifferential diagnosis
2017
Monotherapy Insufficient in Severe Anxiety? Predictors and Moderators in the Child/Adolescent Anxiety Multimodal Study
Taylor JH, Lebowitz ER, Jakubovski E, Coughlin CG, Silverman WK, Bloch MH. Monotherapy Insufficient in Severe Anxiety? Predictors and Moderators in the Child/Adolescent Anxiety Multimodal Study. Journal Of Clinical Child & Adolescent Psychology 2017, 47: 266-281. PMID: 28956620, PMCID: PMC6191182, DOI: 10.1080/15374416.2017.1371028.Peer-Reviewed Original ResearchConceptsChild/Adolescent Anxiety Multimodal StudyCognitive behavioral therapyModerators of outcomeSevere anxietyCombination of CBTIndependent evaluator ratingsMultimodal studyParent-rated anxietySeparation anxiety disorderMain effect findingsObsessive-compulsive disorderAnxious youthSocial anxietyChild anxietyBehavioral therapyAnxiety severityPill placeboAnxiety disordersEvaluators' ratingsAnxietyModeratorSocioeconomic statusLow socioeconomic statusYouthEffect findings