2022
Distinct Symptom Network Structure and Shared Central Social Communication Symptomatology in Autism and Schizophrenia: A Bayesian Network Analysis
Han GT, Trevisan DA, Foss-Feig J, Srihari V, McPartland JC. Distinct Symptom Network Structure and Shared Central Social Communication Symptomatology in Autism and Schizophrenia: A Bayesian Network Analysis. Journal Of Autism And Developmental Disorders 2022, 53: 3636-3647. PMID: 35752729, PMCID: PMC10202012, DOI: 10.1007/s10803-022-05620-0.Peer-Reviewed Original ResearchConceptsSchizophrenia spectrum disordersSocial communication difficultiesSymptom networksCognitive-perceptual symptomsSpectrum disorderRepetitive behaviorsNeurodevelopmental conditionsCommunication difficultiesASDPotential treatment targetAutismSymptom network structureDiagnostic groupsTreatment targetsNetwork analysis approachHigh centralitySymptomatologySchizophreniaSymptomsOrganizationAdultsDisordersBayesian network analysisDifficultiesAnalysis approach
2021
Electrophysiological Studies of Reception of Facial Communication in Autism Spectrum Disorder and Schizophrenia
Levy E, Isenstein E, Foss-Feig J, Srihari V, Anticevic A, Naples A, McPartland J. Electrophysiological Studies of Reception of Facial Communication in Autism Spectrum Disorder and Schizophrenia. Review Journal Of Autism And Developmental Disorders 2021, 9: 521-554. PMID: 36568688, PMCID: PMC9783109, DOI: 10.1007/s40489-021-00260-z.Peer-Reviewed Original ResearchAutism spectrum disorderEvent-related potentialsSchizophrenia spectrum disordersSpectrum disorderFacial communicationResearch Domain Criteria frameworkSocial cognitionHeterogeneous clinical populationN170 latencySocial perceptionTransdiagnostic researchClinical populationsNeural activitySZ populationInconsistent findingsNeurodevelopmental disordersN170Criteria frameworkResearch findingsAreas of overlapDisordersN250CognitionElectrophysiological studiesPerceptionFace Perception Predicts Affective Theory of Mind in Autism Spectrum Disorder but Not Schizophrenia or Typical Development
Altschuler MR, Trevisan DA, Wolf JM, Naples AJ, Foss-Feig JH, Srihari VH, McPartland JC. Face Perception Predicts Affective Theory of Mind in Autism Spectrum Disorder but Not Schizophrenia or Typical Development. Journal Of Psychopathology And Clinical Science 2021, 130: 413-422. PMID: 34180705, PMCID: PMC8244155, DOI: 10.1037/abn0000621.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderBenton Facial Recognition TestSchizophrenia spectrum disordersAffective ToM abilitiesTypical developmentSpectrum disorderAffective ToMToM difficultiesSocial cognitionToM abilitiesIndividual differencesBetter face recognition abilityFace recognition abilityFace recognition difficultiesTheory of mindFacial Recognition TestFull Scale IQFace perceptionAffective theoryRecognition difficultiesRecognition testEyes TestSocial dysfunctionRecognition abilityFace recognition
2020
Drug‐naïve first‐episode schizophrenia spectrum disorders: Pharmacological treatment practices in inpatient units in Hunan Province, China
Zhu M, Ferrara M, Tan W, Shang X, Syed S, Zhang L, Qin Q, Hu X, Rohrbaugh R, Srihari VH, Liu Z. Drug‐naïve first‐episode schizophrenia spectrum disorders: Pharmacological treatment practices in inpatient units in Hunan Province, China. Early Intervention In Psychiatry 2020, 15: 1010-1018. PMID: 32924286, PMCID: PMC8359180, DOI: 10.1111/eip.13046.Peer-Reviewed Original ResearchConceptsSchizophrenia spectrum disordersSingle antipsychoticCurrent guidelinesFirst-episode schizophrenia spectrum disordersAntipsychotic prescription patternsHigh-dose antipsychoticsBest practice treatmentYears of ageElectronic medical recordsClinical characteristicsPrescription patternsClinical factorsInjectable antipsychoticsUntreated illnessMedical recordsFirst episodeAntipsychoticsInpatient unitPolypharmacyPsychiatric hospitalChina GuidelinesInpatientsLogistic regressionPatientsTreatment practices
2018
An Economic Evaluation of Coordinated Specialty Care (CSC) Services for First-Episode Psychosis in the U.S. Public Sector.
Murphy SM, Kucukgoncu S, Bao Y, Li F, Tek C, Breitborde NJK, Guloksuz S, Phutane VH, Ozkan B, Pollard JM, Cahill JD, Woods SW, Cole RA, Schoenbaum M, Srihari VH. An Economic Evaluation of Coordinated Specialty Care (CSC) Services for First-Episode Psychosis in the U.S. Public Sector. The Journal Of Mental Health Policy And Economics 2018, 21: 123-130. PMID: 30530872, PMCID: PMC6314808.Peer-Reviewed Original ResearchConceptsSpecialty care servicesPatient costsEarly intervention servicesUsual treatmentSchizophrenia spectrum disordersMonth 12Economic evaluationCare servicesSTEP participantsCommunity mental health centerThird-party payer perspectiveIntervention servicesFirst-episode servicesMonths post randomizationHealthcare service utilizationMental health centersU.S. public sectorTeam-based careCost-offset analysisEligible patientsThird-party payersAntipsychotic exposureED visitsMonth 6Episode psychosisComparison of Early Intervention Services vs Treatment as Usual for Early-Phase Psychosis: A Systematic Review, Meta-analysis, and Meta-regression
Correll CU, Galling B, Pawar A, Krivko A, Bonetto C, Ruggeri M, Craig TJ, Nordentoft M, Srihari VH, Guloksuz S, Hui CLM, Chen EYH, Valencia M, Juarez F, Robinson DG, Schooler NR, Brunette MF, Mueser KT, Rosenheck RA, Marcy P, Addington J, Estroff SE, Robinson J, Penn D, Severe JB, Kane JM. Comparison of Early Intervention Services vs Treatment as Usual for Early-Phase Psychosis: A Systematic Review, Meta-analysis, and Meta-regression. JAMA Psychiatry 2018, 75: 555-565. PMID: 29800949, PMCID: PMC6137532, DOI: 10.1001/jamapsychiatry.2018.0623.Peer-Reviewed Original ResearchConceptsEarly phase psychosisEarly intervention servicesCause treatment discontinuationSchizophrenia spectrum disordersSymptom severityTreatment discontinuationPsychiatric hospitalizationSystematic reviewIntervention servicesMonths of treatmentEnd of treatmentFirst-episode psychosisTotal symptom severitySystematic literature searchMeta-regression analysisPositive symptom severityCoprimary outcomesPrespecified subgroupsLanguage restrictionsNegative symptom severityClinical trialsTreatment periodMAIN OUTCOMESpectrum disorderPRISMA guidelinesTransforming the Treatment of Schizophrenia in the United States: The RAISE Initiative
Dixon LB, Goldman HH, Srihari VH, Kane JM. Transforming the Treatment of Schizophrenia in the United States: The RAISE Initiative. Annual Review Of Clinical Psychology 2018, 14: 1-22. PMID: 29328779, PMCID: PMC8990328, DOI: 10.1146/annurev-clinpsy-050817-084934.Peer-Reviewed Original ResearchConceptsCoordinated Specialty CareInitial Schizophrenia Episode projectExtensive functional impairmentPatient Outcomes Research TeamTreatment of schizophreniaSchizophrenia spectrum disordersEvidence-based practiceUntreated psychosisSpecialty careChronic schizophreniaCSC programsEpisode ProjectFunctional impairmentLifetime prevalenceRAISE studyRecovery of individualsTreatment settingsEarly interventionNeurodevelopmental illnessSchizophreniaTreatmentUnited StatesInternational studiesSpectrum disorderPatients