2013
Whole-exome sequencing identifies a novel somatic mutation in MMP8 associated with a t(1;22)-acute megakaryoblastic leukemia
Kim Y, Schulz VP, Satake N, Gruber TA, Teixeira AM, Halene S, Gallagher PG, Krause DS. Whole-exome sequencing identifies a novel somatic mutation in MMP8 associated with a t(1;22)-acute megakaryoblastic leukemia. Leukemia 2013, 28: 945-948. PMID: 24157583, PMCID: PMC3981934, DOI: 10.1038/leu.2013.314.Peer-Reviewed Original Research
2006
Allelic dropout in long QT syndrome genetic testing: A possible mechanism underlying false-negative results
Tester D, Cronk L, Carr J, Schulz V, Salisbury B, Judson R, Ackerman M. Allelic dropout in long QT syndrome genetic testing: A possible mechanism underlying false-negative results. Heart Rhythm 2006, 3: 815-821. PMID: 16818214, DOI: 10.1016/j.hrthm.2006.03.016.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAllelesChildChromatography, High Pressure LiquidDNADNA Mutational AnalysisERG1 Potassium ChannelEther-A-Go-Go Potassium ChannelsExonsFalse Negative ReactionsFemaleGene FrequencyHumansKCNQ1 Potassium ChannelLong QT SyndromeMaleMuscle ProteinsMutationNAV1.5 Voltage-Gated Sodium ChannelPolymerase Chain ReactionPolymorphism, Single NucleotidePotassium Channels, Voltage-GatedRetrospective StudiesSodium ChannelsConceptsLong QT syndromeGenetic testingSingle nucleotide polymorphismsIntronic single nucleotide polymorphismLQTS-causing mutationsCongenital long QT syndromeCommon intronic single nucleotide polymorphismHigh clinical probabilityLong QT syndrome genetic testingLQTS genetic testingCardiac channel genes
2001
Haplotype Variation and Linkage Disequilibrium in 313 Human Genes
Stephens J, Schneider J, Tanguay D, Choi J, Acharya T, Stanley S, Jiang R, Messer C, Chew A, Han J, Duan J, Carr J, Lee M, Koshy B, Kumar A, Zhang G, Newell W, Windemuth A, Xu C, Kalbfleisch T, Shaner S, Arnold K, Schulz V, Drysdale C, Nandabalan K, Judson R, Ruaño G, Vovis G. Haplotype Variation and Linkage Disequilibrium in 313 Human Genes. Science 2001, 293: 489-493. PMID: 11452081, DOI: 10.1126/science.1059431.Peer-Reviewed Original ResearchConceptsSingle nucleotide polymorphismsPairs of SNPsLinkage disequilibriumVariable single nucleotide polymorphismsPatterns of variationIndividual single nucleotide polymorphismsHaplotype variationBiological traitsHuman genesDiverse ancestryDifferent haplotypesGenesNucleotide polymorphismsHuman populationUnrelated individualsHaplotypesRecent expansionPopulation frequencyDisequilibriumTraitsAncestryImportant implicationsInformation contentPolymorphismPopulation
1991
Translation initiation of IS50R read-through transcripts
Schulz V, Reznikoff W. Translation initiation of IS50R read-through transcripts. Journal Of Molecular Biology 1991, 221: 65-80. PMID: 1717696, DOI: 10.1016/0022-2836(91)80205-9.Peer-Reviewed Original ResearchConceptsRNA secondary structureTranslation initiationSecondary structureRibosome binding siteRNA secondary structure analysisPotential RNA secondary structureSecondary structure analysisEffects of mutationsTransposase proteinTransposase geneIS50RNormal transcriptTransposase expressionTranscriptsInsertion sequenceBinding sitesMutationsGenesTransposaseReadsStructure analysisProteinOuter endLow levelsSequence
1990
In vitro secondary structure analysis of mRNA from lacZ translation initiation mutants
Schulz V, Reznikoff W. In vitro secondary structure analysis of mRNA from lacZ translation initiation mutants. Journal Of Molecular Biology 1990, 211: 427-445. PMID: 2106583, DOI: 10.1016/0022-2836(90)90363-q.Peer-Reviewed Original ResearchConceptsTranslation initiation regionSecondary structure analysisStem-loop structureTranslation initiationSecondary structureRNA transcriptsInitiation regionMRNA secondary structureTranslation initiation efficiencyRNA secondary structureInitiation mutantMutant RNAsStructure analysisRNATranscriptsMutations
1989
Pseudorevertants of a lac promoter mutation reveal overlapping nascent promoters
Karls R, Schulz V, Jovanovich S, Flynn S, Pak A, Reznikoff W. Pseudorevertants of a lac promoter mutation reveal overlapping nascent promoters. Nucleic Acids Research 1989, 17: 3927-3949. PMID: 2499870, PMCID: PMC317870, DOI: 10.1093/nar/17.10.3927.Peer-Reviewed Original Research