Suboptimal Sleep Duration Is Associated With Poorer Neuroimaging Brain Health Profiles in Middle‐Aged Individuals Without Stroke or Dementia
Clocchiatti‐Tuozzo S, Rivier C, Renedo D, Lopez V, Geer J, Miner B, Yaggi H, de Havenon A, Payabvash S, Sheth K, Gill T, Falcone G. Suboptimal Sleep Duration Is Associated With Poorer Neuroimaging Brain Health Profiles in Middle‐Aged Individuals Without Stroke or Dementia. Journal Of The American Heart Association 2023, 13: e031514. PMID: 38156552, PMCID: PMC10863828, DOI: 10.1161/jaha.123.031514.Peer-Reviewed Original ResearchConceptsSuboptimal sleep durationWhite matter hyperintensitiesMiddle-aged individualsLong sleep durationLarger WMH volumeSleep durationMiddle-aged adultsHealth profileWMH volumeAmerican Heart Association's LifeAsymptomatic middle-aged adultsWMH presenceVolume of WMHOptimal sleepSelf-reported sleep durationModifiable risk factorsWhite matter tractsProspective magnetic resonanceSimple 7Cardiovascular healthRisk factorsShort sleepMatter hyperintensitiesHigh riskEarly interventionAssociations Between Frailty and the Increased Risk of Adverse Outcomes Among 38,950 UK Biobank Participants With Prediabetes: Prospective Cohort Study
Cao X, Li X, Zhang J, Sun X, Yang G, Zhao Y, Li S, Hoogendijk E, Wang X, Zhu Y, Allore H, Gill T, Liu Z. Associations Between Frailty and the Increased Risk of Adverse Outcomes Among 38,950 UK Biobank Participants With Prediabetes: Prospective Cohort Study. JMIR Public Health And Surveillance 2023, 9: e45502. PMID: 37200070, PMCID: PMC10236284, DOI: 10.2196/45502.Peer-Reviewed Original ResearchConceptsMultiple adverse outcomesChronic kidney diseaseDiabetes-related microvascular diseaseAdverse outcomesCause mortalityCardiovascular diseaseMiddle-aged adultsUK Biobank participantsHigh riskMicrovascular diseaseEye diseaseIncident type 2 diabetes mellitusType 2 diabetes mellitusProportional hazards regression modelsBiobank participantsMultivariable-adjusted modelsProspective cohort studyHazards regression modelsNormal glucose metabolismDiabetes-related burdenDiabetes-related diseasesHealth care resourcesNonfrail counterpartsFrailty assessmentCohort study