2021
AGA Clinical Practice Guidelines on Intragastric Balloons in the Management of Obesity
Muniraj T, Day LW, Teigen LM, Ho EY, Sultan S, Davitkov P, Shah R, Murad MH. AGA Clinical Practice Guidelines on Intragastric Balloons in the Management of Obesity. Gastroenterology 2021, 160: 1799-1808. PMID: 33832655, DOI: 10.1053/j.gastro.2021.03.003.Peer-Reviewed Original Research
2020
Musculoskeletal Pain Symptoms and Injuries Among Endoscopists Who Perform ERCP
Campbell EV, Muniraj T, Aslanian HR, Laine L, Jamidar P. Musculoskeletal Pain Symptoms and Injuries Among Endoscopists Who Perform ERCP. Digestive Diseases And Sciences 2020, 66: 56-62. PMID: 32144599, DOI: 10.1007/s10620-020-06163-z.Peer-Reviewed Original ResearchConceptsEndoscopic retrograde cholangiopancreatographyMusculoskeletal pain symptomsPain symptomsRisk factorsMusculoskeletal injuriesPrevalent musculoskeletal injuriesDe Quervain's tenosynovitisPotential risk factorsRisk of injuryAnonymous electronic surveyNeck painBack painQuervain's tenosynovitisRetrograde cholangiopancreatographyResultsA totalPreventative strategiesConclusionsThe majorityInjurySymptomsEndoscopistsProtective gearMultiple studiesHalf reportTenosynovitisElectronic survey
2019
Genetic Risk Score in Diabetes Associated With Chronic Pancreatitis Versus Type 2 Diabetes Mellitus
Goodarzi MO, Nagpal T, Greer P, Cui J, Chen YI, Guo X, Pankow JS, Rotter JI, Alkaade S, Amann ST, Baillie J, Banks PA, Brand RE, Conwell DL, Cote GA, Forsmark CE, Gardner TB, Gelrud A, Guda N, LaRusch J, Lewis MD, Money ME, Muniraj T, Papachristou GI, Romagnuolo J, Sandhu BS, Sherman S, Singh VK, Wilcox CM, Pandol SJ, Park WG, Andersen DK, Bellin MD, Hart PA, Yadav D, Whitcomb DC. Genetic Risk Score in Diabetes Associated With Chronic Pancreatitis Versus Type 2 Diabetes Mellitus. Clinical And Translational Gastroenterology 2019, 10: e00057. PMID: 31232720, PMCID: PMC6708663, DOI: 10.14309/ctg.0000000000000057.Peer-Reviewed Original ResearchConceptsGenetic risk scoreDiabetes mellitusChronic pancreatitisCP-DMPancreatogenic diabetesRisk scoreNorth American Pancreatitis Study 2Type 2 diabetes mellitusLarge prospective studiesSingle nucleotide polymorphismsMulti-Ethnic StudyWeighted genetic risk scoreMean genetic risk scoreDiabetic groupNondiabetic controlsProspective studyNucleotide polymorphismsPathophysiologic entityFamily historyT2DMDiabetesType 2Separate disordersGold standardMellitusChronic Pancreatitis
Schwarzenberg SJ, Uc A, Zimmerman B, Wilschanski M, Wilcox CM, Whitcomb DC, Werlin SL, Troendle D, Tang G, Slivka A, Singh VK, Sherman S, Shah U, Sandhu BS, Romagnuolo J, Rhee S, Pohl JF, Perito ER, Ooi CY, Nathan JD, Muniraj T, Morinville VD, McFerron B, Mascarenhas M, Maqbool A, Liu Q, Lin TK, Lewis M, Husain SZ, Himes R, Heyman MB, Guda N, Gonska T, Giefer MJ, Gelrud A, Gariepy CE, Gardner TB, Freedman SD, Forsmark CE, Fishman DS, Cote GA, Conwell D, Brand RE, Bellin M, Barth B, Banks PA, Anderson MA, Amann ST, Alkaade S, Abu‐El‐Haija M, Abberbock JN, Lowe ME, Yadav D. Chronic Pancreatitis. Journal Of Pediatric Gastroenterology And Nutrition 2019, 68: 566-573. PMID: 30897605, PMCID: PMC6492264, DOI: 10.1097/mpg.0000000000002279.Peer-Reviewed Original ResearchConceptsChronic pancreatitisRisk factorsGenetic risk factorsOnly risk factorEmergency room visitsInternational Study GroupAge of onsetWork/schoolDisease durationPediatric pancreatitisRoom visitsDiabetes prevalenceRadiographic findingsAppropriate statistical testsPancreatic insufficiencyChildhood onsetStudy groupSecondary analysisCohortNatural historyPancreatitisCP treatmentAdultsChildrenLength of timeIncreased awareness enhances physician recognition of the role of smoking in chronic pancreatitis
Muniraj T, Yadav D, Abberbock JN, Alkaade S, Amann ST, Anderson MA, Banks PA, Brand RE, Conwell D, Cote GA, Forsmark CE, Gardner TB, Gelrud A, Guda N, Lewis MD, Romagnuolo J, Sandhu BS, Sherman S, Singh VK, Slivka A, Tang G, Whitcomb DC, Wilcox CM. Increased awareness enhances physician recognition of the role of smoking in chronic pancreatitis. Pancreatology 2019, 19: 500-506. PMID: 30910452, PMCID: PMC6619496, DOI: 10.1016/j.pan.2019.02.009.Peer-Reviewed Original ResearchConceptsCP risk factorsPack/dayRisk factorsPhysician recognitionSmoking statusAS studiesIdentification of smokingPancreatitis risk factorsRole of smokingRisk of CPPhysician questionnairesStructured patientAlcohol etiologyCP patientsPast smokersChronic pancreatitisMultivariable analysisSmoking ratesUS CentersSmokingEmpiric dataPatientsPhysiciansWide-spread disseminationEtiology
2018
Cannabis Use Is Associated With Increased Risk of Post–Endoscopic Retrograde Cholangiopancreatography Pancreatitis
Njei B, Sharma P, McCarty TR, Singh M, Haque L, Aslanian HR, Jamidar P, Muniraj T. Cannabis Use Is Associated With Increased Risk of Post–Endoscopic Retrograde Cholangiopancreatography Pancreatitis. Pancreas 2018, 47: 1142-1149. PMID: 30134357, DOI: 10.1097/mpa.0000000000001143.Peer-Reviewed Original ResearchConceptsPost-endoscopic retrograde cholangiopancreatography pancreatitisIncidence risk ratioCholangiopancreatography pancreatitisCannabis useRisk of PEPEndoscopic retrograde cholangiopancreatography pancreatitisUS Nationwide Inpatient SampleRate of PEPShorter hospital stayNationwide Inpatient SampleNinth Edition codesImpact of cannabisPoisson regression modelsHospital deathHospital stayIndependent predictorsEdition codesRisk ratioInpatient SampleInternational ClassificationMultivariate analysisPancreatitisPatientsCannabisSignificant increaseBarrett's esophagus: A comprehensive review for the internist
Klavan H, Russell MB, Macklin J, Lee E, Aslanian HR, Muniraj T. Barrett's esophagus: A comprehensive review for the internist. Disease-a-Month 2018, 64: 471-487. PMID: 29880269, DOI: 10.1016/j.disamonth.2018.04.001.Peer-Reviewed Original ResearchRecurrent Acute Pancreatitis Significantly Reduces Quality of Life Even in the Absence of Overt Chronic Pancreatitis
Coté GA, Yadav D, Abberbock JA, Whitcomb DC, Sherman S, Sandhu BS, Anderson MA, Lewis MD, Alkaade S, Singh VK, Baillie J, Banks PA, Conwell D, Guda NM, Muniraj T, Tang G, Brand R, Gelrud A, Amann ST, Forsmark CE, Wilcox C, Slivka A, Gardner TB. Recurrent Acute Pancreatitis Significantly Reduces Quality of Life Even in the Absence of Overt Chronic Pancreatitis. The American Journal Of Gastroenterology 2018, 113: 906-912. PMID: 29867178, PMCID: PMC6136830, DOI: 10.1038/s41395-018-0087-7.Peer-Reviewed Original ResearchConceptsMental component summary scoresRecurrent acute pancreatitisLower physical component summaryPhysical component summaryQuality of lifeChronic pancreatitisAcute pancreatitisLower mental component summary scoresMental QOLLower QOLShort Form-12Component summary scoresCross-sectional studyMultivariable regression modelsNon-disease controlsEndocrine insufficiencyComponent summaryIndependent predictorsForm-12CP subjectsPancreatitisSummary scoresObjectivesThe impactU.S. CentersQOL predictors
2017
Patient and Disease Characteristics Associated With the Presence of Diabetes Mellitus in Adults With Chronic Pancreatitis in the United States
Bellin MD, Whitcomb DC, Abberbock J, Sherman S, Sandhu BS, Gardner TB, Anderson MA, Lewis MD, Alkaade S, Singh VK, Baillie J, Banks PA, Conwell D, Cote GA, Guda NM, Muniraj T, Tang G, Brand RE, Gelrud A, Amann ST, Forsmark CE, Wilcox CM, Slivka A, Yadav D. Patient and Disease Characteristics Associated With the Presence of Diabetes Mellitus in Adults With Chronic Pancreatitis in the United States. The American Journal Of Gastroenterology 2017, 112: 1457. PMID: 28741615, PMCID: PMC6168293, DOI: 10.1038/ajg.2017.181.Peer-Reviewed Original ResearchConceptsDiabetes mellitusChronic pancreatitisRisk factorsPancreas surgeryFamily historyType 2 diabetes mellitusMultivariate logistic regression modelingDM risk factorsLarge multicenter cohortStrong risk factorCross-sectional assessmentLogistic regression modelingCommon complicationCP patientsPatient demographicsMulticenter cohortExocrine insufficiencyPancreatic calcificationSingle centerDisease characteristicsDM diagnosisMultivariable modelSingle etiologyHigher oddsPatientsValidation of Demographics, Etiology, and Risk Factors for Chronic Pancreatitis in the USA: A Report of the North American Pancreas Study (NAPS) Group
Conwell DL, Banks PA, Sandhu BS, Sherman S, Al-Kaade S, Gardner TB, Anderson MA, Wilcox CM, Lewis MD, Muniraj T, Forsmark CE, Cote GA, Guda NM, Tian Y, Romagnuolo J, Wisniewski SR, Brand R, Gelrud A, Slivka A, Whitcomb DC, Yadav D. Validation of Demographics, Etiology, and Risk Factors for Chronic Pancreatitis in the USA: A Report of the North American Pancreas Study (NAPS) Group. Digestive Diseases And Sciences 2017, 62: 2133-2140. PMID: 28600657, PMCID: PMC6040886, DOI: 10.1007/s10620-017-4621-z.Peer-Reviewed Original ResearchConceptsRisk factorsIdiopathic etiologyEpidemiologic trendsChronic pancreatitis patientsRecent epidemiologic trendsMultiple risk factorsCurrent epidemiologic trendsNAPS2 studyAlcohol etiologyCP patientsYounger patientsChronic pancreatitisCommon etiologyPancreatitis patientsMean ageConclusionOur dataUS CentersStudy groupEtiologyObjectivesOur aimPatientsGenetic etiologySmokingDemographic factorsValidation study
2016
Racial Differences in the Clinical Profile, Causes, and Outcome of Chronic Pancreatitis
Wilcox CM, Sandhu BS, Singh V, Gelrud A, Abberbock JN, Sherman S, Cote GA, Al-Kaade S, Anderson MA, Gardner TB, Lewis MD, Forsmark CE, Guda NM, Romagnuolo J, Baillie J, Amann ST, Muniraj T, Tang G, Conwell DL, Banks PA, Brand RE, Slivka A, Whitcomb D, Yadav D. Racial Differences in the Clinical Profile, Causes, and Outcome of Chronic Pancreatitis. The American Journal Of Gastroenterology 2016, 111: 1488. PMID: 27527745, PMCID: PMC6196097, DOI: 10.1038/ajg.2016.316.Peer-Reviewed Original ResearchMeSH KeywordsAbdominal PainAdultAgedAtrophyBlack or African AmericanCalcinosisCommon Bile Duct DiseasesConstriction, PathologicExocrine Pancreatic InsufficiencyFemaleHumansMaleMiddle AgedPain MeasurementPancreasPancreatic DiseasesPancreatic DuctsPancreatitis, AlcoholicPancreatitis, ChronicPrevalenceProspective StudiesRisk FactorsSex FactorsSmokingTime FactorsWhite PeopleYoung AdultConceptsChronic pancreatitisBlack patientsClinical profileDuration of CPNorth American Pancreatitis StudiesDuration of diseaseAlcoholic chronic pancreatitisProgression of pancreatitisRacial differencesPrior cholecystectomyPain characteristicsAlcohol etiologyCurrent smokersDisease durationSevere painEndoscopic treatmentWhite patientsRisk factorsPancreatic morphologyUS CentersEpidemiologic studiesPatientsAdvanced changesRetrospective dataDetailed questionnaireClinical Profile, Etiology, and Treatment of Chronic Pancreatitis in North American Women
Romagnuolo J, Talluri J, Kennard E, Sandhu BS, Sherman S, Cote GA, Al-Kaade S, Gardner TB, Gelrud A, Lewis MD, Forsmark CE, Guda NM, Conwell DL, Banks PA, Muniraj T, Wisniewski SR, Tian Y, Wilcox CM, Anderson MA, Brand RE, Slivka A, Whitcomb DC, Yadav D. Clinical Profile, Etiology, and Treatment of Chronic Pancreatitis in North American Women. Pancreas 2016, 45: 934-940. PMID: 26967451, PMCID: PMC4940220, DOI: 10.1097/mpa.0000000000000616.Peer-Reviewed Original ResearchConceptsChronic pancreatitisNonalcoholic etiologyMulticenter US cohortEndocrine insufficiencyAlcohol etiologyClinical profileMedical therapyNorth American womenUS cohortRisk factorsChronic diseasesMorphologic findingsAlcoholic malesPain experienceCP casesClinical phenotypeEtiologyDetailed questionnaireWomenDiseaseAmerican womenPancreatitisPatientsRecent dataDemographics
2014
Chronic pancreatitis, a comprehensive review and update. Part I: Epidemiology, etiology, risk factors, genetics, pathophysiology, and clinical features
Muniraj T, Aslanian HR, Farrell J, Jamidar PA. Chronic pancreatitis, a comprehensive review and update. Part I: Epidemiology, etiology, risk factors, genetics, pathophysiology, and clinical features. Disease-a-Month 2014, 60: 530-550. PMID: 25510320, DOI: 10.1016/j.disamonth.2014.11.002.Peer-Reviewed Original Research
2012
Diabetes and pancreatic cancer.
Muniraj T, Chari ST. Diabetes and pancreatic cancer. Minerva Gastroenterology 2012, 58: 331-45. PMID: 23207610, PMCID: PMC3932318.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsBody Mass IndexClinical Trials as TopicDiabetes Mellitus, Type 2Early Detection of CancerEvidence-Based MedicineGlobal HealthGlucose IntoleranceHumansHyperinsulinismHypoglycemic AgentsInsulin GlargineInsulin, Long-ActingMeta-Analysis as TopicMetforminObesityPancreatic NeoplasmsPrevalenceRisk AssessmentRisk FactorsConceptsType 2 diabetesNew-onset diabetesPancreatic cancerPancreatic cancer-associated diabetesAnti-diabetic medicationsDuration of diseasePancreatic cancer patientsYears of ageGlucose toleranceCancer patientsOnset diabetesHigh riskEpidemiological studiesDiabetesCancerAdditional markersModest increaseRiskInverse relationshipRecent studiesMedicationsPatientsDisease