2021
The rural Uganda non-communicable disease (RUNCD) study: prevalence and risk factors of self-reported NCDs from a cross sectional survey
Siddharthan T, Kalyesubula R, Morgan B, Ermer T, Rabin TL, Kayongo A, Munana R, Anton N, Kast K, Schaeffner E, Kirenga B, Knauf F. The rural Uganda non-communicable disease (RUNCD) study: prevalence and risk factors of self-reported NCDs from a cross sectional survey. BMC Public Health 2021, 21: 2036. PMID: 34743687, PMCID: PMC8572568, DOI: 10.1186/s12889-021-12123-7.Peer-Reviewed Original ResearchConceptsSelf-reported hypertensionSelf-reported chronic diseasesNon-communicable Disease studyChronic disease informationRural Ugandan districtSelf-reported diseasesDiagnosis of diabetesCross-sectional surveyMiddle-income settingsBaseline demographicsMale sexKidney diseasePatient cohortResultsA totalHealth districtRisk factorsChronic diseasesDisease cohortHypertensionLower oddsNCD prevalenceAverage ageSectional surveyHealth statusDisease
2016
Oxalate, inflammasome, and progression of kidney disease
Ermer T, Eckardt KU, Aronson PS, Knauf F. Oxalate, inflammasome, and progression of kidney disease. Current Opinion In Nephrology & Hypertension 2016, 25: 363-371. PMID: 27191349, PMCID: PMC4891250, DOI: 10.1097/mnh.0000000000000229.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsChronic kidney diseaseProgressive renal failureRenal inflammationRenal failurePlasma oxalateKidney diseaseInflammasome activationElevated plasma oxalate levelsNOD-like receptor familyProgressive renal damageGlomerular filtration rateMore rapid progressionWarrants clinical trialsPlasma oxalate levelsRenal damageEnteric hyperoxaluriaMacrophage infiltrationIL-1βFiltration rateClinical trialsRapid progressionInflammasome proteinsMice protectsUrinary oxalatePyrin domain