2022
Plant mitochondrial FMT and its mammalian homolog CLUH controls development and behavior in Arabidopsis and locomotion in mice
Ralevski A, Apelt F, Olas JJ, Mueller-Roeber B, Rugarli EI, Kragler F, Horvath TL. Plant mitochondrial FMT and its mammalian homolog CLUH controls development and behavior in Arabidopsis and locomotion in mice. Cellular And Molecular Life Sciences 2022, 79: 334. PMID: 35652974, PMCID: PMC11071973, DOI: 10.1007/s00018-022-04382-3.Peer-Reviewed Original ResearchConceptsMitochondrial genesWhole plant morphologySalt stress responseNormal growth conditionsLeaf expansion growthArabidopsis thalianaHigher eukaryotesGene familyMitochondrial proteinsPlant morphologyHomologous functionsMitochondrial morphologyExpansion growthStress responseMitochondrial functionAnimal speciesPlantsSimilar roleGrowth conditionsHeterozygous knockout miceGenesDevelopmental alterationsKnockout miceCLUHArabidopsis
2021
Mitochondrial Fission Governed by Drp1 Regulates Exogenous Fatty Acid Usage and Storage in Hela Cells
Song JE, Alves TC, Stutz B, Šestan-Peša M, Kilian N, Jin S, Diano S, Kibbey RG, Horvath TL. Mitochondrial Fission Governed by Drp1 Regulates Exogenous Fatty Acid Usage and Storage in Hela Cells. Metabolites 2021, 11: 322. PMID: 34069800, PMCID: PMC8157282, DOI: 10.3390/metabo11050322.Peer-Reviewed Original ResearchExogenous fatty acidsMitochondrial fissionMitochondrial fatty acid oxidationFatty acid oxidationFatty acid usageMitochondrial morphologyLipid dropletsAcid usageCarnitine palmitoyltransferase 1HeLa cellsDynamin-related proteinKey mitochondrial proteinsFatty acidsAcid oxidationMitochondrial proteinsLipid droplet accumulationMitochondrial dynamicsNovel functionLipid homeostasisHigh abundanceDirect roleDroplet accumulationMitochondriaFatty acid contentProtein