2013
Natural birth-induced UCP2 in brain development
Seli E, Horvath TL. Natural birth-induced UCP2 in brain development. Reviews In Endocrine And Metabolic Disorders 2013, 14: 347-350. PMID: 23979530, DOI: 10.1007/s11154-013-9262-8.Peer-Reviewed Original ResearchConceptsVaginal birthPost-operative surgical careLong-term outcomesEarly postnatal periodWild-type littermatesAdult brain structureUCP2 mRNA expressionTerm outcomesSurgical techniqueSurgical carePostnatal periodSurgical meansHippocampal formationMore deliveriesSynapse formationAxonal outgrowthC-sectionKnockout animalsMRNA expressionUCP2 expressionBrain developmentBrain structuresNeuronal differentiationBirthHippocampus
2012
Ucp2 Induced by Natural Birth Regulates Neuronal Differentiation of the Hippocampus and Related Adult Behavior
Simon-Areces J, Dietrich MO, Hermes G, Garcia-Segura LM, Arevalo MA, Horvath TL. Ucp2 Induced by Natural Birth Regulates Neuronal Differentiation of the Hippocampus and Related Adult Behavior. PLOS ONE 2012, 7: e42911. PMID: 22905184, PMCID: PMC3414493, DOI: 10.1371/journal.pone.0042911.Peer-Reviewed Original ResearchConceptsUCP2 expressionCellular stressHippocampal neuronsChemical inhibitionMitochondrial bioenergeticsNeuronal differentiationGenetic ablationNatural birthProtein 2Adult behaviorCell proliferationCritical roleAdult brainNeuronal numberExpressionBioenergeticsNeuronsBirthDifferentiationRegulationProliferationSynaptogenesisVitroNeuroprotectionHippocampus