2023
Cohort Profile: The Rajarata Pregnancy Cohort (RaPCo)
Agampodi S, Wickramasinghe N, Agampodi T. Cohort Profile: The Rajarata Pregnancy Cohort (RaPCo). Anuradhapura Medical Journal 2023, 17: 31. DOI: 10.4038/amj.v17i1.7757.Peer-Reviewed Original ResearchMaternal morbidityFirst trimesterPregnancy cohortPregnant womenFirst antenatal clinic visitEarly pregnancy miscarriageFatty liver gradePregnancy care programsFatty liver indexGestational age neonatesAntenatal clinic visitPregnancy outcome dataAnemic pregnant womenSignificant risk factorsComprehensive mental healthBaseline data collectionGestational diabetesAge neonatesClinic visitsCohort womenMetabolic syndromeMetabolic derangementsEarly pregnancyEntire cohortLiver indexEarly pregnancy metabolic syndrome and risk for adverse pregnancy outcomes: findings from Rajarata Pregnancy Cohort (RaPCo) in Sri Lanka
Jayasinghe I, Agampodi T, Dissanayake A, Agampodi S. Early pregnancy metabolic syndrome and risk for adverse pregnancy outcomes: findings from Rajarata Pregnancy Cohort (RaPCo) in Sri Lanka. BMC Pregnancy And Childbirth 2023, 23: 231. PMID: 37020187, PMCID: PMC10074348, DOI: 10.1186/s12884-023-05548-y.Peer-Reviewed Original ResearchConceptsGestational agePreterm birthPregnancy outcomesPregnant womenMetabolic syndromePregnancy cohortJoint Interim Statement criteriaFirst trimester pregnant womenMajor pregnancy outcomesSouth Asian pregnant womenAdverse pregnancy outcomesNeonatal birth weightGestational weight gainMedian gestational ageProspective cohort studyLive singleton birthsSignificant risk predictorAsian pregnant womenConclusionPregnant womenFPG thresholdMetS prevalenceCohort studyCumulative incidenceProspective cohortMetS definitions
2022
Non-Alcoholic Fatty Liver Disease Among Pregnant Women With Metabolic Syndrome: Should Nutritional Intervention Be a Priority? A Cross Sectional Study in Rural Sri Lanka
Koralegedara I, Warnasekara J, Jayasinghe I, Agampodi T, Agampodi S, Dayaratne K. Non-Alcoholic Fatty Liver Disease Among Pregnant Women With Metabolic Syndrome: Should Nutritional Intervention Be a Priority? A Cross Sectional Study in Rural Sri Lanka. Current Developments In Nutrition 2022, 6: 680. PMCID: PMC9194234, DOI: 10.1093/cdn/nzac061.064.Peer-Reviewed Original ResearchNon-alcoholic fatty liver diseaseProportion of NAFLDFatty liver diseaseMetS groupMetabolic syndromeNutritional interventionPregnant mothersAminotransferase levelsLiver diseaseAlcoholic fatty liver diseaseGamma-glutamyl transferase levelsCross-sectional comparative studyNon-MetS participantsAdverse pregnancy outcomesAlanine aminotransferase levelsInternational Diabetes FederationDetailed clinical examinationAspartate aminotransferase levelsAmerican Heart AssociationCross-sectional studyGlutamyl transferase levelsTime of recruitmentWorld Health OrganizationAnuradhapura districtMean domeComparison of global definitions of metabolic syndrome in early pregnancy among the Rajarata Pregnancy Cohort participants in Sri Lanka
Jayasinghe IU, Agampodi TC, Dissanayake AK, Srimantha SM, Agampodi SB. Comparison of global definitions of metabolic syndrome in early pregnancy among the Rajarata Pregnancy Cohort participants in Sri Lanka. Scientific Reports 2022, 12: 2009. PMID: 35132136, PMCID: PMC8821546, DOI: 10.1038/s41598-022-05919-z.Peer-Reviewed Original ResearchConceptsPeriod of gestationTotal cholesterolEarly pregnancyMetabolic syndromeMetabolic derangementsCohort participantsPrevalence estimatesOral glucose tolerance testHigher MetS prevalenceNCEP ATP IIIAHA/NHLBIGlucose tolerance testDifferent diagnostic criteriaSignificant differencesCross-sectional analysisAge 27.9MetS prevalencePregnancy outcomesSerum lipidsMetS definitionsProspective studyPregnant womenPlasma glucoseTolerance testMetabolic parameters