2022
Non-alcoholic fatty liver disease (NAFLD): a significant predictor of gestational diabetes mellitus (GDM) and early pregnancy miscarriages—prospective study in Rajarata Pregnancy Cohort (RaPCo)
Koralegedara IS, Warnasekara JN, Dayaratne KG, De Silva FN, Premadasa JK, Agampodi SB. Non-alcoholic fatty liver disease (NAFLD): a significant predictor of gestational diabetes mellitus (GDM) and early pregnancy miscarriages—prospective study in Rajarata Pregnancy Cohort (RaPCo). BMJ Open Gastroenterology 2022, 9: e000831. PMID: 35193889, PMCID: PMC8867246, DOI: 10.1136/bmjgast-2021-000831.Peer-Reviewed Original ResearchConceptsNon-alcoholic fatty liver diseaseGestational diabetes mellitusEarly pregnancy miscarriageFatty liver diseasePregnancy miscarriageRisk factorsDiabetes mellitusLiver diseasePregnant womenRelative riskEffect of NAFLDImpact of NAFLDPopulation-based prospective cohort studyRepeat oral glucose tolerance testFirst trimester pregnant womenOral glucose tolerance testPregnancy care programsProspective cohort studyOnly independent predictorBody mass indexGlucose tolerance testWeeks of gestationSignificant risk factorsMajor risk factorHigh-risk mothersEarly pregnancy hyperglycaemia as a significant predictor of large for gestational age neonates
Jayasinghe IU, Koralegedara IS, Agampodi SB. Early pregnancy hyperglycaemia as a significant predictor of large for gestational age neonates. Acta Diabetologica 2022, 59: 535-543. PMID: 34973071, PMCID: PMC8917036, DOI: 10.1007/s00592-021-01828-1.Peer-Reviewed Original ResearchConceptsGestational diabetes mellitusGestational age neonatesLGA neonatesAge neonatesGestational ageFirst trimesterPrevalence of GDMWorld Health Organization criteriaDelivery gestational ageNeonatal birth weightPregnancy Study GroupsBirth weight centileMedian gestational ageProspective cohort studyAttributable risk percentageHigh-risk populationUndiagnosed DMCohort studyCumulative incidenceDiabetes mellitusWeight centileEarly pregnancyPregnant womenMean ageOrganization criteria
2019
Comparison of biochemical parameters among DPP4 inhibitor users and other oral hypoglycaemic drug users: a cross-sectional study from Anuradhapura, Sri Lanka
Rathish D, Jayasumana C, Agampodi S. Comparison of biochemical parameters among DPP4 inhibitor users and other oral hypoglycaemic drug users: a cross-sectional study from Anuradhapura, Sri Lanka. Journal Of Health, Population And Nutrition 2019, 38: 3. PMID: 30674350, PMCID: PMC6343272, DOI: 10.1186/s41043-019-0160-x.Peer-Reviewed Original ResearchConceptsDPP4 inhibitor usersCross-sectional studyDrug usersInhibitor usersDipeptidyl peptidase-4 inhibitor treatmentType 2 diabetes mellitusComparative cross-sectional studyBiochemical parametersIncretin-based therapiesMann-Whitney U testSignificant differencesHigh lipase levelsPrevious Asian studiesDPP4i groupDPP4i usersOral hypoglycaemicsALT levelsDiabetes mellitusLipase levelsDPP4 inhibitorsSerum lipaseInhibitor treatmentU testPancreatic amylaseHbA1c
2016
From organophosphate poisoning to diabetes mellitus: The incretin effect
Rathish D, Agampodi SB, Jayasumana MACS, Siribaddana SH. From organophosphate poisoning to diabetes mellitus: The incretin effect. Medical Hypotheses 2016, 91: 53-55. PMID: 27142144, DOI: 10.1016/j.mehy.2016.04.002.Peer-Reviewed Original ResearchConceptsAccumulation of acetylcholineIncretin effectGlucose homeostasisDiabetes mellitusOP poisoningType 2 diabetes mellitusPeptide-1 secretionAcute OPMuscarinic receptorsTreatment modalitiesOrganophosphate poisoningPositive findingsInhibition of acetylcholinesterasesMellitusInduced disruptionHomeostasisPoisoningInhibitionDisruptionT2DMAcetylcholineGlucagonIncidenceSecretionReceptors
2013
Predictive validity of Post Prandial Blood Sugar (PPBS) at booking visit and routine urine dip stick test (UDST) in detecting Gestational Diabetes Mellitus (GDM)
Ranasinghe O, Dahanayaka N, Agampodi S. Predictive validity of Post Prandial Blood Sugar (PPBS) at booking visit and routine urine dip stick test (UDST) in detecting Gestational Diabetes Mellitus (GDM). Anuradhapura Medical Journal 2013, 6: 39. DOI: 10.4038/amj.v6i1.5772.Peer-Reviewed Original ResearchExpectant fathers’ knowledge of maternal morbidity: a Sri Lankan experience
Weekrakkody A, Weerasinghe GM, Weerasinghe MP, Weerasekara GL, Agampodi SB. Expectant fathers’ knowledge of maternal morbidity: a Sri Lankan experience. F1000Research 2013, 2: 119. PMID: 25309724, PMCID: PMC4184315, DOI: 10.12688/f1000research.2-119.v1.Peer-Reviewed Original ResearchGestational diabetes mellitusPregnancy Induced HypertensionExpectant fathersCross-sectional descriptive studyAnuradhapura Teaching HospitalHealth promotional programsSectional descriptive studyPregnant women's healthInduced hypertensionMaternal morbidityAntenatal clinicDiabetes mellitusSecond pregnancyMaternal healthRisk factorsTeaching hospitalMedian numberHigher scoresKruskal-Wallis testWomen's healthAge groupsPregnancyMale partnersAnemiaDescriptive study
2012
Inadequacy of the risk factor based approach to detect gestational diabetes mellitus
Dahanayaka N, Agampodi S, Ranasinghe O, Jayaweera P, Wickramasinghe W, Adhikari A, Chathurani H, Dissanayaka U. Inadequacy of the risk factor based approach to detect gestational diabetes mellitus. Ceylon Medical Journal 2012, 57: 5-9. PMID: 22453704, DOI: 10.4038/cmj.v57i1.4193.Peer-Reviewed Original ResearchConceptsGestational diabetes mellitusRisk factorsIADPSG criteriaPregnant womenDiabetes mellitusPrevalence of GDMOral glucose tolerance testCross-sectional descriptive studyEligible pregnant womenPregnancy Study GroupsGlucose tolerance testSectional descriptive studyPresent risk factorsGDM patientsGDM casesGestational ageWHO criteriaPlasma glucoseTolerance testStudy groupStudy populationDescriptive studyMedical officersHealth areaMellitus
2011
Screening for gestational diabetes mellitus in Anuradhapura district
Dahanayaka N, Agampodi S, Ranasinghe O, Jayaweera P, Fernando S. Screening for gestational diabetes mellitus in Anuradhapura district. Ceylon Medical Journal 2011, 56: 128-9. PMID: 22164754, DOI: 10.4038/cmj.v56i3.3608.Peer-Reviewed Original Research