2024
Altered neuroepithelial morphogenesis and migration defects in iPSC-derived cerebral organoids and 2D neural stem cells in familial bipolar disorder
Phalnikar K, Srividya M, Mythri S, Vasavi N, Ganguly A, Kumar A, S P, Kalia K, Mishra S, Dhanya S, Paul P, Holla B, Ganesh S, Reddy P, Sud R, Viswanath B, Muralidharan B. Altered neuroepithelial morphogenesis and migration defects in iPSC-derived cerebral organoids and 2D neural stem cells in familial bipolar disorder. Oxford Open Neuroscience 2024, 3: kvae007. PMID: 38638145, PMCID: PMC11024480, DOI: 10.1093/oons/kvae007.Peer-Reviewed Original ResearchPatient organoidsNeural stem cellsBipolar disorderStem cellsTranscriptome analysis of controlPatient-derived organoidsFamilial bipolar disorderMigration defectsNeural stem cell culturesDysregulation of genesFamilial BDBD patientsCausative genetic variantsSox2-positiveNeurodevelopmental aberrationsNeurodevelopmental anomaliesIPSC-derived cerebral organoidsProgenitor proliferationStem cell culturesAbnormal positionPatientsNeuronal migrationCortical organoidsMolecular deficitsCycling progenitors
2023
The Acute Effects of Cannabinoids in Patients with Psychotic Illness
Ganesh S, Henquet C, Sewell R, Kuepper R, Ranganathan M, D’Souza D. The Acute Effects of Cannabinoids in Patients with Psychotic Illness. 2023, 225-239. DOI: 10.1017/9781108943246.023.Peer-Reviewed Original ResearchMental illnessMental health teamsHealth policy implicationsHigh-potency cannabisStages of neurodevelopmentPotential adverse effectsAcute effectsHealth teamsPsychotic illnessImpact of exposureCannabis dependenceAdverse effectsIllnessCannabisCannabinoidsSynthetic cannabinoidsPsychosisNew research findingsAssociationComplex associationPatientsNeurodevelopmentPutative modelSchizophrenia
2018
Six months' course and outcome of metabolic abnormalities in a cohort of patients with schizophrenia in rural India
Bijjal S, Ganesh S, Rawat V, Agarwal V, Reddy K, Devi N, Kumar C, Christopher R, Thirthalli J. Six months' course and outcome of metabolic abnormalities in a cohort of patients with schizophrenia in rural India. Schizophrenia Research 2018, 201: 415-416. PMID: 29880456, DOI: 10.1016/j.schres.2018.05.016.Peer-Reviewed Original Research
2017
A Case of Carbamazepine-induced Severe Cholestatic Hepatitis: Case Report and Review of Literature
Ganesh S, Shukla L, Kandasamy A, Benegal V. A Case of Carbamazepine-induced Severe Cholestatic Hepatitis: Case Report and Review of Literature. Indian Journal Of Psychological Medicine 2017, 39: 688-690. PMID: 29200572, PMCID: PMC5688903, DOI: 10.4103/ijpsym.ijpsym_19_17.Peer-Reviewed Case Reports and Technical NotesSevere cholestatic hepatitisCholestatic hepatitisDrug-induced liver injuryCausality assessment scaleFemale patient presentingInitiation of carbamazepineReview of literatureLiver injuryClinical manifestationsPatient presentingCase reportPrescribed drugsAssessment ScaleField of neuropsychiatryHepatitisCarbamazepinePatientsPresentingEtiopathogenesisInjuryPrevalence and predictors of metabolic syndrome in patients with schizophrenia and healthy controls: A study in rural South Indian population
Rawat V, Ganesh S, Bijjal S, Reddy K, Agarwal V, Devi R, Kumar C, Christopher R, Thirthalli J. Prevalence and predictors of metabolic syndrome in patients with schizophrenia and healthy controls: A study in rural South Indian population. Schizophrenia Research 2017, 192: 102-107. PMID: 28454923, DOI: 10.1016/j.schres.2017.04.039.Peer-Reviewed Original ResearchConceptsPredictors of MetSGeneral population controlsAntipsychotic exposureMetabolic syndromeOdds ratioFemale genderRural south Indian populationInternational Diabetes Federation criteriaDiagnosis of MetSSubgrouping of patientsPhysical activity patternsSouth Indian populationPopulation controlsFederation criteriaClinical parametersSouth IndiaTreatment detailsHealthy controlsIndependent riskLow prevalenceGeneral populationTreatment groupsPatientsSchizophrenia patientsControl group
2016
Prevalence and determinants of metabolic syndrome in patients with schizophrenia: A systematic review and meta-analysis of Indian studies
Ganesh S, Ashok A, Kumar C, Thirthalli J. Prevalence and determinants of metabolic syndrome in patients with schizophrenia: A systematic review and meta-analysis of Indian studies. Asian Journal Of Psychiatry 2016, 22: 86-92. PMID: 27520904, DOI: 10.1016/j.ajp.2016.05.006.Peer-Reviewed Original ResearchConceptsMetabolic syndromePooled prevalenceSchizophrenia patientsLow prevalenceSystematic reviewNCEP ATP III criteriaDeterminants of MetSDrug-naïve patientsCase-control designUnderstanding of prevalenceHospital studyHigh prevalenceHospital settingPrevalence ratesPatientsScience Direct databasesCommunity settingsSyndromePrevalenceLiterature searchIndian studiesHospitalSchizophreniaGoogle ScholarConflicting results