2024
Further evidence for the association between childhood trauma and suicidal ideation in young individuals: A twin based study
Moreno-Gamazo N, Pries L, Marqués-Feixa L, Papiol S, Romero S, Menne-Lothmann C, Decoster J, van Winkel R, Collip D, Delespaul P, De Hert M, Derom C, Thiery E, Jacobs N, Wichers M, van Os J, Rutten B, Fañanás L, Guloksuz S. Further evidence for the association between childhood trauma and suicidal ideation in young individuals: A twin based study. Journal Of Affective Disorders 2024, 370: 118-123. PMID: 39488234, DOI: 10.1016/j.jad.2024.10.125.Peer-Reviewed Original ResearchChildhood traumaSuicidal ideationPsychiatric evaluation of patientsSCL-90-R.Environmental risk factorsGene-environment correlationHistory of CTSample of twinsTwin analysesGenetic vulnerabilityPsychiatric evaluationRisk factorsTwin studiesTwin pairsPhysical abuseEvaluation of patientsDizygotic twinsGenetic riskIdeationProtective factorsPsychosocial environmentIndividual characteristicsGenetic predispositionIncreased riskTotal CT
2023
Gene–environment interaction study on the polygenic risk score for neuroticism, childhood adversity, and parental bonding
Klingenberg B, Guloksuz S, Pries L, Cinar O, Menne-Lothmann C, Decoster J, van Winkel R, Collip D, Delespaul P, De Hert M, Derom C, Thiery E, Jacobs N, Wichers M, Lin B, Luykx J, van Os J, Rutten B. Gene–environment interaction study on the polygenic risk score for neuroticism, childhood adversity, and parental bonding. Personality Neuroscience 2023, 6: e5. PMID: 38107775, PMCID: PMC10725776, DOI: 10.1017/pen.2023.2.Peer-Reviewed Original ResearchChildhood adversityParental bondingLife eventsPositive life eventsNegative life eventsGene-environment correlationGenetic vulnerabilityEysenck Personality QuestionnaireParental bonding stylesExpression of neuroticismPaternal bondingNeuroticismPersonality QuestionnaireAdversityMultilevel mixed-effects modelsMaternal bonding
2020
Polygenic liability for schizophrenia and childhood adversity influences daily‐life emotion dysregulation and psychosis proneness
Pries L, Klingenberg B, Menne‐Lothmann C, Decoster J, van Winkel R, Collip D, Delespaul P, De Hert M, Derom C, Thiery E, Jacobs N, Wichers M, Cinar O, Lin B, Luykx J, Rutten B, van Os J, Guloksuz S. Polygenic liability for schizophrenia and childhood adversity influences daily‐life emotion dysregulation and psychosis proneness. Acta Psychiatrica Scandinavica 2020, 141: 465-475. PMID: 32027017, PMCID: PMC7318228, DOI: 10.1111/acps.13158.Peer-Reviewed Original ResearchConceptsDaily life stressorsChildhood adversityEmotion dysregulationPositive affectPsychosis pronenessMomentary mental statesEcological momentary assessmentChildhood Trauma QuestionnaireGene-environment correlationNegative affectMental statesMomentary assessmentPsychosis expressionTrauma QuestionnaireAdversityAffectYoung adultsStressorsNovel evidencePolygenic liabilityInteraction effectsPronenessSchizophreniaHigh PRSState domain