2022
Exposome and Trans-syndromal Developmental Trajectories Toward Psychosis
Barzilay R, Pries L, Moore T, Gur R, van Os J, Rutten B, Guloksuz S. Exposome and Trans-syndromal Developmental Trajectories Toward Psychosis. Biological Psychiatry Global Open Science 2022, 2: 197-205. PMID: 36325037, PMCID: PMC9616341, DOI: 10.1016/j.bpsgos.2022.05.001.Peer-Reviewed Original ResearchEnvironmental exposuresEarly life environmental exposuresNonspecific clinical presentationClinical presentationTrajectories of riskClinical settingPrenatal periodMental healthDevelopmental cohortGenetic factorsEarly childhoodYounger cohortsCategorical outcomesSensitive periodCohortDevelopmental disordersAdolescent psychopathology
2019
Psychometric liability to psychosis and childhood adversities are associated with shorter telomere length: A study on schizophrenia patients, unaffected siblings, and non-clinical controls
Çevik B, Mançe-Çalışır Ö, Atbaşoğlu E, Saka M, Alptekin K, Üçok A, Sırmatel B, Gülöksüz S, Tükün A, van Os J, Gümüş-Akay G. Psychometric liability to psychosis and childhood adversities are associated with shorter telomere length: A study on schizophrenia patients, unaffected siblings, and non-clinical controls. Journal Of Psychiatric Research 2019, 111: 169-185. PMID: 30776705, DOI: 10.1016/j.jpsychires.2019.01.022.Peer-Reviewed Original ResearchConceptsShorter telomere lengthLonger telomere lengthChildhood adversityTelomere lengthUnaffected siblingsSCZ patientsChronic medical disordersCourse of schizophreniaSimilar telomere lengthPsychotic-like symptomsHypothesis patientsClinical presentationNon-clinical controlsMedical disordersGeneral populationFunctioning scoresPatientsSchizophrenia patientsSocio-demographic featuresGlobal assessmentEarly onsetSchizophreniaLife expectancyAges 0Potential role