2024
F85. GENETIC OVERLAP OF BRAIN STRUCTURE AND CONNECTIVITY WITH SCHIZOPHRENIA: DIFFERENT STATISTICAL METHODS PROVIDE COMPLEMENTARY INSIGHTS
Wu X, Parekh P, Lin B, Pries L, Guloksuz S, Rutten B, Andreassen O, Linden D, van der Meer D. F85. GENETIC OVERLAP OF BRAIN STRUCTURE AND CONNECTIVITY WITH SCHIZOPHRENIA: DIFFERENT STATISTICAL METHODS PROVIDE COMPLEMENTARY INSIGHTS. European Neuropsychopharmacology 2024, 87: 251. DOI: 10.1016/j.euroneuro.2024.08.496.Peer-Reviewed Original ResearchConcordant effect directionsLinkage disequilibrium score regressionGenome-wide association study dataCell adhesion molecule bindingGenetic architectureBrain measuresPolygenic scoresBrain phenotypesUnique genesGene OntologyBrain structuresConjunctional false discovery rateLinkage disequilibrium score regression analysisGenetic correlationsGenetic risk of schizophreniaComplex genetic architectureHeritable brain disorderKyoto Encyclopedia of GenesAssociated with schizophreniaInsignificant genetic correlationResting-state fMRIWhite matter integrityEncyclopedia of GenesPostsynaptic densityRisk of schizophrenia
2023
T15. THE ADDITIVE VALUE OF BRAIN LIFESTYLE IN THE EXPLANATORY ABILITY OF POLYGENIC RISK PROFILES ON COGNITIVE PERFORMANCE IN AGING INDIVIDUALS
Zhang Y, Gülöksüz S, Stehouwer C, Greevenbroek M, Köhler S, Eussen S, Bosma H, Boxtel M, Schram M, Linden D, Rutten B, Blokland G. T15. THE ADDITIVE VALUE OF BRAIN LIFESTYLE IN THE EXPLANATORY ABILITY OF POLYGENIC RISK PROFILES ON COGNITIVE PERFORMANCE IN AGING INDIVIDUALS. European Neuropsychopharmacology 2023, 75: s169-s170. DOI: 10.1016/j.euroneuro.2023.08.303.Peer-Reviewed Original ResearchPolygenic risk scoresCognitive domainsCognitive functionHeritability of cognitive functionsEffect of polygenic risk scoresEnvironmental influencesThe Maastricht StudyPotential cognitive deficitsOverall cognitive functionBrain health indexImpact cognitive healthRisk factorsGenetic predispositionGene-environment interactionsCardio-metabolic diseasesLIBRA scoresNon-adjusted modelCognitive phenotypesCognitive deficitsCognitive performanceCognitive healthLifestyle factorsOverall cognitionBrain structuresMental health
2013
Metabolic syndrome prevalence in different affective temperament profiles in bipolar-I disorder
Altinbas K, Guloksuz S, Oral E. Metabolic syndrome prevalence in different affective temperament profiles in bipolar-I disorder. Brazilian Journal Of Psychiatry 2013, 35: 131-135. PMID: 23904017, DOI: 10.1590/1516-4446-2011-0746.Peer-Reviewed Original ResearchConceptsMetabolic syndrome prevalenceDevelopment of MetSInternational Diabetes FederationMetabolic syndrome markersMood Disorders UnitSan Diego-Autoquestionnaire versionProportion of MetSDepressive temperament scoresAffective temperament profilesMetS prevalenceDiabetes FederationSyndrome prevalenceDisorders unitBipolar patientsBrain structuresSocioeconomic statusTemperament EvaluationPatientsMetSPrevalenceTemperament profilesTemperament scoresTemperamental profilesMetS.