2015
The impact of electroconvulsive therapy on the tryptophan–kynurenine metabolic pathway
Guloksuz S, Arts B, Walter S, Drukker M, Rodriguez L, Myint A, Schwarz M, Ponds R, van Os J, Kenis G, Rutten B. The impact of electroconvulsive therapy on the tryptophan–kynurenine metabolic pathway. Brain Behavior And Immunity 2015, 48: 48-52. PMID: 25765557, DOI: 10.1016/j.bbi.2015.02.029.Peer-Reviewed Original ResearchConceptsTrp-Kyn pathwayHamilton Depression Rating Scale-17 itemsElectroconvulsive therapyBeck Depression InventoryMechanism of actionKynurenic acidTrp-KynKyn/Trp ratioKYNA/KYN ratioTryptophan-kynurenine metabolic pathwayLast ECT sessionBilateral electroconvulsive therapyKyn/TrpTreatment of depressionMultilevel linear regression analysesKYN metabolitesECT sessionsAntidepressant effectsECT responseBipolar depressionECT treatmentTrp ratioNeuroprotective propertiesKynurenine pathwayNeurotoxic processes
2014
Clinical Features of Night Eating Syndrome among Depressed Patients
Kucukgoncu S, Tek C, Bestepe E, Musket C, Guloksuz S. Clinical Features of Night Eating Syndrome among Depressed Patients. European Eating Disorders Review 2014, 22: 102-108. PMID: 24436087, DOI: 10.1002/erv.2280.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAnxiety DisordersBody Mass IndexCircadian RhythmDepressionFeeding and Eating DisordersFeeding BehaviorFemaleHumansInterviews as TopicMaleMiddle AgedObesityPersonality InventoryPrevalencePsychiatric Status Rating ScalesQuality of LifeRegression AnalysisSocioeconomic FactorsStress, PsychologicalSurveys and QuestionnairesSyndromeYoung AdultConceptsPittsburgh Sleep Quality IndexBeck Depression InventoryBeck Anxiety InventoryClinical featuresDepressed patientsDepression InventoryNon-NE patientsNight eating syndromeSleep Quality IndexSample of patientsAnxiety InventorySeverity of anxietyNight Eating QuestionnaireSocio-demographic formSmoking statusDaytime dysfunctionSleep qualityDepressed outpatientsPatientsSyndromeEating QuestionnaireStudy sampleBMISignificant differencesDepression