2023
Gene–environment interaction study on the polygenic risk score for neuroticism, childhood adversity, and parental bonding
Klingenberg B, Guloksuz S, Pries L, Cinar O, Menne-Lothmann C, Decoster J, van Winkel R, Collip D, Delespaul P, De Hert M, Derom C, Thiery E, Jacobs N, Wichers M, Lin B, Luykx J, van Os J, Rutten B. Gene–environment interaction study on the polygenic risk score for neuroticism, childhood adversity, and parental bonding. Personality Neuroscience 2023, 6: e5. PMID: 38107775, PMCID: PMC10725776, DOI: 10.1017/pen.2023.2.Peer-Reviewed Original ResearchChildhood adversityParental bondingLife eventsPositive life eventsNegative life eventsGene-environment correlationGenetic vulnerabilityEysenck Personality QuestionnaireParental bonding stylesExpression of neuroticismPaternal bondingNeuroticismPersonality QuestionnaireAdversityMultilevel mixed-effects modelsMaternal bonding
2020
Resilience in psychosis spectrum disorder
Pries L, Guloksuz S, Rutten B. Resilience in psychosis spectrum disorder. 2020, 476-484. DOI: 10.1093/med/9780190653279.003.0053.Peer-Reviewed Original ResearchPsychosis spectrum disordersSpectrum disorderPsychological growthResilience factorsResilience researchFuture research directionsProtective factorsSocial factorsResilienceResearch directionsDifferent time pointsProspective studyDisordersAdversityLife spanTime pointsFirst evidenceResearchVulnerabilitySwift recoverySpanIllnessFactorsPolygenic liability for schizophrenia and childhood adversity influences daily‐life emotion dysregulation and psychosis proneness
Pries L, Klingenberg B, Menne‐Lothmann C, Decoster J, van Winkel R, Collip D, Delespaul P, De Hert M, Derom C, Thiery E, Jacobs N, Wichers M, Cinar O, Lin B, Luykx J, Rutten B, van Os J, Guloksuz S. Polygenic liability for schizophrenia and childhood adversity influences daily‐life emotion dysregulation and psychosis proneness. Acta Psychiatrica Scandinavica 2020, 141: 465-475. PMID: 32027017, PMCID: PMC7318228, DOI: 10.1111/acps.13158.Peer-Reviewed Original ResearchConceptsDaily life stressorsChildhood adversityEmotion dysregulationPositive affectPsychosis pronenessMomentary mental statesEcological momentary assessmentChildhood Trauma QuestionnaireGene-environment correlationNegative affectMental statesMomentary assessmentPsychosis expressionTrauma QuestionnaireAdversityAffectYoung adultsStressorsNovel evidencePolygenic liabilityInteraction effectsPronenessSchizophreniaHigh PRSState domain