2001
pH-dependent conformational flexibility within the ribosomal peptidyl transferase center.
Muth G, Chen L, Kosek A, Strobel S. pH-dependent conformational flexibility within the ribosomal peptidyl transferase center. RNA 2001, 7: 1403-15. PMID: 11680845, PMCID: PMC1370184.Peer-Reviewed Original ResearchInvestigation of adenosine base ionization in the hairpin ribozyme by nucleotide analog interference mapping.
Ryder S, Oyelere A, Padilla J, Klostermeier D, Millar D, Strobel S. Investigation of adenosine base ionization in the hairpin ribozyme by nucleotide analog interference mapping. RNA 2001, 7: 1454-63. PMID: 11680850, PMCID: PMC1370189.Peer-Reviewed Original ResearchAdenosineBase SequenceCatalysisNucleic Acid ConformationNucleotidesRNA, CatalyticTranscription, Genetic
1999
Nucleotide Analog Interference Mapping
Ryder S, Strobel S. Nucleotide Analog Interference Mapping. Methods 1999, 18: 38-50. PMID: 10208815, DOI: 10.1006/meth.1999.0755.Peer-Reviewed Original ResearchMeSH KeywordsAdenosineGuanosineModels, ChemicalModels, GeneticNucleotide MappingPhosphorusPyrimidinesRNAThionucleotidesTranscription, GeneticConceptsFunctional groupsActive moleculesGroup substitutionNucleotide analog interference mappingIncorporation propertiesIndividual analoguesMoleculesSeries 5AnaloguesSubstitution experimentsGel electrophoresisInterference mappingUnique biochemical signatureSubstitutionSynthesisNucleoside analog triphosphatesActivity assaysBiochemical informationReactionAnalog substitutionsAssayable functionChemogenetic approachRNA structureNucleotide analoguesIodine
1998
Identifying RNA Minor Groove Tertiary Contacts by Nucleotide Analogue Interference Mapping with N 2-Methylguanosine †
Ortoleva-Donnelly L, Kronman M, Strobel S. Identifying RNA Minor Groove Tertiary Contacts by Nucleotide Analogue Interference Mapping with N 2-Methylguanosine †. Biochemistry 1998, 37: 12933-12942. PMID: 9737873, DOI: 10.1021/bi980723j.Peer-Reviewed Original Research