2015
Burden of Comorbidities and Functional and Cognitive Impairments in Elderly Patients at the Initial Diagnosis of Heart Failure and Their Impact on Total Mortality The Cardiovascular Health Study
Murad K, Goff DC, Morgan TM, Burke GL, Bartz TM, Kizer JR, Chaudhry SI, Gottdiener JS, Kitzman DW. Burden of Comorbidities and Functional and Cognitive Impairments in Elderly Patients at the Initial Diagnosis of Heart Failure and Their Impact on Total Mortality The Cardiovascular Health Study. JACC Heart Failure 2015, 3: 542-550. PMID: 26160370, PMCID: PMC4499113, DOI: 10.1016/j.jchf.2015.03.004.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAgedAged, 80 and overAtrial FibrillationCognition DisordersCohort StudiesComorbidityCoronary DiseaseFemaleHeart FailureHumansHypertensionIncidenceLongitudinal StudiesMalePeripheral Arterial DiseasePhysical FitnessPrevalenceProportional Hazards ModelsPulmonary Disease, Chronic ObstructiveConceptsIncident heart failureCardiovascular Health StudyHeart failureGreater mortality riskMortality riskPercent of participantsCognitive impairmentElderly patientsFunctional impairmentDaily livingHealth StudyBurden of comorbiditiesChronic kidney diseaseMultivariable-adjusted modelsTotal mortality riskRelevant comorbiditiesDiabetes mellitusInitial diagnosisCerebrovascular diseaseKidney diseaseMean ageHigh burdenComorbiditiesInstrumental activitiesMortality rate
2011
Impact of Comorbidity on Mortality Among Older Persons with Advanced Heart Failure
Ahluwalia SC, Gross CP, Chaudhry SI, Ning YM, Leo-Summers L, Van Ness PH, Fried TR. Impact of Comorbidity on Mortality Among Older Persons with Advanced Heart Failure. Journal Of General Internal Medicine 2011, 27: 513-519. PMID: 22095572, PMCID: PMC3326095, DOI: 10.1007/s11606-011-1930-3.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overChronic DiseaseCohort StudiesComorbidityFemaleHeart DiseasesHeart FailureHip FracturesHospitalizationHumansKaplan-Meier EstimateKidney DiseasesLongitudinal StudiesMaleMedicarePrevalencePrognosisPulmonary Disease, Chronic ObstructiveRetrospective StudiesRisk FactorsUnited StatesConceptsChronic obstructive pulmonary diseaseImpact of comorbiditiesAdvanced heart failureHeart failureHigher mortality riskMortality riskComorbidity burdenHip fractureMyocardial infarctionOlder adultsCount of conditionsOverall comorbidity burdenRetrospective cohort studyContribution of comorbiditiesObstructive pulmonary diseaseProportional hazards regressionLower mortality riskLife-prolonging interventionsHF mortalityHospitalized beneficiariesMost comorbiditiesCohort studyIndividual comorbiditiesPrior hospitalizationPulmonary disease