1993
Pigmentation and Proliferation of Human Melanocytes and the Effects of Melanocyte‐Stimulating Hormone and Ultraviolet B Lighta
HALABAN R, TYRRELL L, LONGLEY J, YARDEN Y, RUBIN J. Pigmentation and Proliferation of Human Melanocytes and the Effects of Melanocyte‐Stimulating Hormone and Ultraviolet B Lighta. Annals Of The New York Academy Of Sciences 1993, 680: 290-301. PMID: 7685575, DOI: 10.1111/j.1749-6632.1993.tb19691.x.Peer-Reviewed Original Research
1988
Sequence analysis of mouse tyrosinase cDNA and the effect of melanotropin on its gene expression
Kwon B, Wakulchik M, Haq A, Halaban R, Kestler D. Sequence analysis of mouse tyrosinase cDNA and the effect of melanotropin on its gene expression. Biochemical And Biophysical Research Communications 1988, 153: 1301-1309. PMID: 3134020, DOI: 10.1016/s0006-291x(88)81370-6.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceBase SequenceCatechol OxidaseCloning, MolecularDNAGene Expression RegulationHumansMelanocyte-Stimulating HormonesMolecular Sequence DataMonophenol MonooxygenaseConceptsAmino acid sequenceAcid sequenceTyrosinase cDNAPotential N-glycosylation sitesMouse genomic cloneHistidine-rich regionMouse tyrosinase geneN-glycosylation sitesLevels of transcriptsCopper-binding siteMouse tyrosinase cDNADeduced proteinGenomic clonesTransmembrane sequenceHuman tyrosinase cDNACDNA clonesMouse tyrosinaseTyrosinase geneGene expressionSequence analysisAmino acidsHuman tyrosinaseClonesCDNAMelanoma cells
1987
A melanocyte-specific complementary DNA clone whose expression is inducible by melanotropin and isobutylmethyl xanthine.
Kwon B, Halaban R, Kim G, Usack L, Pomerantz S, Haq A. A melanocyte-specific complementary DNA clone whose expression is inducible by melanotropin and isobutylmethyl xanthine. Molecular Biology & Medicine 1987, 4: 339-55. PMID: 2449595.Peer-Reviewed Original ResearchMeSH Keywords1-Methyl-3-isobutylxanthineAnimalsAntibodies, MonoclonalCatechol OxidaseDNAGene Expression RegulationGlycoproteinsHumansMelaninsMelanocytesMelanocyte-Stimulating HormonesMelanomaMelanoma, ExperimentalMiceMonophenol MonooxygenaseNeoplasm ProteinsPigmentationSpecies SpecificityTheophyllineTumor Cells, CulturedConceptsPmel 17CDNA clonesLambda gt11 cDNA libraryComplementary DNA cloneHuman tyrosinase geneNormal human melanocytesSingle geneDNA clonesCDNA libraryStimulation of humanMRNA speciesTyrosinase geneMurine melanocytesMurine DNAMurine melanoma cellsRestriction fragmentsHuman melanocytesRepresentative clonesGenesClonesImmunological homologyCDNAMelanoma cellsMelanocytesSpecies
1984
Tyrosinase activity and abundance in Cloudman melanoma cells
Halaban R, Pomerantz S, Marshall S, Lerner A. Tyrosinase activity and abundance in Cloudman melanoma cells. Archives Of Biochemistry And Biophysics 1984, 230: 383-387. PMID: 6201140, DOI: 10.1016/0003-9861(84)90121-8.Peer-Reviewed Original Research
1983
Regulation of tyrosinase in human melanocytes grown in culture.
Halaban R, Pomerantz S, Marshall S, Lambert D, Lerner A. Regulation of tyrosinase in human melanocytes grown in culture. Journal Of Cell Biology 1983, 97: 480-488. PMID: 6411733, PMCID: PMC2112541, DOI: 10.1083/jcb.97.2.480.Peer-Reviewed Original ResearchMeSH KeywordsCatechol OxidaseCells, CulturedChemical PrecipitationHumansMelanocytesMelanocyte-Stimulating HormonesMelanomaMonophenol MonooxygenaseSkin PigmentationConceptsHuman melanocytesApparent molecular weightMalignant human melanocytesTyrosinase activityMajor biochemical eventsExpression of tyrosinaseSynthesis of melaninRegulation of tyrosinasePosttranslational modificationsImmunoprecipitation experimentsO-glycosylationBiochemical eventsNormal melanocytesMelanocytesMolecular weightProteinEnzymeTyrosinaseTunicamycinAbundanceActivityRegulationHigh levelsLow levelsCulture
1980
Supermelanotic hybrids derived from mouse melanomas and normal mouse cells
Halaban R, Nordlund J, Francke U, Moellmann G, Eisenstadt J. Supermelanotic hybrids derived from mouse melanomas and normal mouse cells. Somatic Cell Genetics 1980, 6: 29-44. PMID: 6768142, DOI: 10.1007/bf01538694.Peer-Reviewed Original Research
1977
The dual effect of melanocyte-stimulating hormone (MSH) on the growth of cultured mouse melanoma cells
Halaban R, Lerner A. The dual effect of melanocyte-stimulating hormone (MSH) on the growth of cultured mouse melanoma cells. Experimental Cell Research 1977, 108: 111-117. PMID: 196867, DOI: 10.1016/s0014-4827(77)80016-5.Peer-Reviewed Original ResearchMeSH KeywordsCell DivisionCell LineCulture MediaCyclic AMPDose-Response Relationship, DrugMelanocyte-Stimulating HormonesMonophenol MonooxygenaseTyrosineConceptsMelanocyte stimulating hormoneMouse melanoma cellsMelanoma cellsInhibition of growthTyrosinase activityIntracellular levelsRate of proliferationExogenous adenosineLow tyrosinase activityCyclic monophosphateHormoneDual effectHigh tyrosinase activityStimulationCellsActivation of tyrosinaseInhibitionStimulation of growthCulture mediumToxic substancesTyrosinase and inhibition of proliferation of melanoma cells and fibroblasts
Halaban R, Lerner A. Tyrosinase and inhibition of proliferation of melanoma cells and fibroblasts. Experimental Cell Research 1977, 108: 119-125. PMID: 408156, DOI: 10.1016/s0014-4827(77)80017-7.Peer-Reviewed Original ResearchMeSH KeywordsCell DivisionCell LineDNAMelanocyte-Stimulating HormonesMonophenol MonooxygenaseTyrosine
1975
Melanoma cells resistant to inhibition of growth by melanocyte stimulating hormone.
Pawelek J, Sansone M, Koch N, Christie G, Halaban R, Hendee J, Lerner A, Varga J. Melanoma cells resistant to inhibition of growth by melanocyte stimulating hormone. Proceedings Of The National Academy Of Sciences Of The United States Of America 1975, 72: 951-955. PMID: 165495, PMCID: PMC432441, DOI: 10.1073/pnas.72.3.951.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCatechol OxidaseCell DivisionCell LineCyclic AMPDNA, NeoplasmMelanocyte-Stimulating HormonesMelanomaMiceNeoplasms, ExperimentalPhenotypeProtein KinasesReceptors, Cell Surface