2022
Cocaine Use Disorder (CUD): Current Clinical Perspectives
Schwartz EKC, Wolkowicz NR, De Aquino JP, MacLean RR, Sofuoglu M. Cocaine Use Disorder (CUD): Current Clinical Perspectives. Substance Abuse And Rehabilitation 2022, 13: 25-46. PMID: 36093428, PMCID: PMC9451050, DOI: 10.2147/sar.s337338.Peer-Reviewed Original ResearchCocaine use disorderCo-occurring disordersUse disordersCommon co-occurring disordersCurrent clinical perspectivesSubstance use disordersCognitive behavioral therapyMedication treatmentPharmacological treatmentRisk factorsCurrent treatmentDevastating disorderLarger sample sizeTreatment planChronic effectsCocaine useBehavioral treatmentClinical perspectiveBehavioral interventionsDisordersTreatmentFuture studiesMost individualsIndividualsSample size
2021
The Impact of Chronic Pain on Opioid Use Disorder Treatment Outcomes
MacLean R, Spinola S, Garcia-Vassallo G, Sofuoglu M. The Impact of Chronic Pain on Opioid Use Disorder Treatment Outcomes. Current Addiction Reports 2021, 8: 100-108. DOI: 10.1007/s40429-020-00352-6.Peer-Reviewed Original ResearchOpioid agonist treatmentChronic painOpioid use disorderOpioid Use Disorder Treatment OutcomesNonpharmacologic pain treatmentsIllicit opioid useDisorder treatment outcomesReviewChronic painOpioid usePain intensityPain treatmentAgonist treatmentOAT clinicsTreatment outcomesClinical carePainUse disordersDrug useRecent FindingsWeHigher likelihoodClinicOutcomesTreatmentMost studiesIntake
2020
Complex Persistent Opioid Dependence with Long-term Opioids: a Gray Area That Needs Definition, Better Understanding, Treatment Guidance, and Policy Changes
Manhapra A, Sullivan MD, Ballantyne JC, MacLean RR, Becker WC. Complex Persistent Opioid Dependence with Long-term Opioids: a Gray Area That Needs Definition, Better Understanding, Treatment Guidance, and Policy Changes. Journal Of General Internal Medicine 2020, 35: 964-971. PMID: 33159241, PMCID: PMC7728942, DOI: 10.1007/s11606-020-06251-w.Peer-Reviewed Original ResearchConceptsLong-term opioid therapyOpioid taperingOpioid dependenceChronic pain refractoryUtilization of buprenorphineLong-term opioidsSevere chronic painOpioid use disorderMultitude of treatmentsLimited supportive evidenceOpioid therapyPain refractoryBuprenorphine treatmentChronic painClinical instabilityRecent guidelinesClinical definitionUS adultsUse disordersDiagnosis/Treatment guidancePainComplicationsTreatmentSupportive evidence
2019
Stress and opioid use disorder: A systematic review
MacLean RR, Armstrong JL, Sofuoglu M. Stress and opioid use disorder: A systematic review. Addictive Behaviors 2019, 98: 106010. PMID: 31238237, DOI: 10.1016/j.addbeh.2019.05.034.Peer-Reviewed Original ResearchConceptsOpioid use disorderOpioid useTreatment retentionUse disordersSystematic reviewOUD treatment outcomesIllicit opioid useWarrants further studySignificant clinical concernOUD outcomesStandard treatmentTreatment outcomesDrug counselingPsychopharmacological interventionsClinical concernBehavioral treatmentGreater cravingBehavioral interventionsStudy sampleFurther studiesTreatmentAssessment of stressInterventionImpact of stressMultiple databases
2018
Stimulants and Mood Disorders
MacLean R, Sofuoglu M. Stimulants and Mood Disorders. Current Addiction Reports 2018, 5: 323-329. DOI: 10.1007/s40429-018-0212-0.Peer-Reviewed Original ResearchStimulant use disorderMood disordersUse disordersSUD comorbidityClinical trialsComorbid substance use disorderRecent FindingsEpidemiological studiesCo-occurring mood disordersSubstance use disordersMethamphetamine use disorderMajority of trialsClinical outcomesPharmacological treatmentTreatment responseNeurobiological mechanismsDisordersMultiple studiesTrialsComorbiditiesPatientsDiagnosisMoodTreatmentPurposeToEpidemiology