2016
Willingness to Use Pre-Exposure Prophylaxis (PrEP): An Empirical Test of the Information-Motivation-Behavioral Skills (IMB) Model among High-Risk Drug Users in Treatment
Shrestha R, Altice FL, Huedo-Medina TB, Karki P, Copenhaver M. Willingness to Use Pre-Exposure Prophylaxis (PrEP): An Empirical Test of the Information-Motivation-Behavioral Skills (IMB) Model among High-Risk Drug Users in Treatment. AIDS And Behavior 2016, 21: 1299-1308. PMID: 27990587, PMCID: PMC5380590, DOI: 10.1007/s10461-016-1650-0.Peer-Reviewed Original ResearchConceptsHigh-risk PWUDBehavioral skills modelCommunity-based methadone maintenance treatmentPre-exposure prophylaxis trialsSex-related HIV risk behaviorsHigh-risk drug usersPre-exposure prophylaxisIMB modelMethadone maintenance treatmentEfficacy of PrEPUse of PrEPHIV risk behaviorsKey risk populationsHealth behavior changeHIV acquisitionProphylaxis trialsHIV infectionMaintenance treatmentHIV preventionRisk populationsDrug usersRisk behaviorsPrEPPWUDIntervention developmentModeling a Theory-Based Approach to Examine the Influence of Neurocognitive Impairment on HIV Risk Reduction Behaviors Among Drug Users in Treatment
Huedo-Medina TB, Shrestha R, Copenhaver M. Modeling a Theory-Based Approach to Examine the Influence of Neurocognitive Impairment on HIV Risk Reduction Behaviors Among Drug Users in Treatment. AIDS And Behavior 2016, 20: 1646-1657. PMID: 27052845, PMCID: PMC4945437, DOI: 10.1007/s10461-016-1394-x.Peer-Reviewed Original ResearchConceptsNeurocognitive impairmentCommunity-based methadone maintenance treatmentHIV risk reduction informationSex-related HIV risk behaviorsHIV risk reduction behaviorsHigh-risk PWUDHIV prevention benefitsMethadone maintenance treatmentHIV prevention outcomesOpioid-dependent individualsSignificant neurocognitive impairmentHIV risk behaviorsHIV prevention behaviorsRisk reduction informationHealth behavior changeBehavioral skills modelRisk reduction behaviorsRisk reduction outcomesMaintenance treatmentEfficacious interventionsDrug usersPrevention benefitsPrevention outcomesPrevention behaviorsRisk behaviorsThe Impact of Methadone Maintenance Treatment on HIV Risk Behaviors among High-Risk Injection Drug Users: A Systematic Review.
Karki P, Shrestha R, Huedo-Medina TB, Copenhaver M. The Impact of Methadone Maintenance Treatment on HIV Risk Behaviors among High-Risk Injection Drug Users: A Systematic Review. Evidence-based Medicine & Public Health 2016, 2 PMID: 27066590, PMCID: PMC4824190.Peer-Reviewed Original ResearchMethadone maintenance treatmentInjection drug usersSex-related risk behaviorsHIV risk behaviorsRisk behaviorsMaintenance treatmentDrug usersSystematic reviewHigh-risk injection drug usersFuture HIV prevention strategiesRisk Injection Drug UsersSex-related HIV risk behaviorsHigh-risk populationHIV prevention strategiesSignificant decreaseMultiple sex partnersPreventable drugHIV infectionTreatment adherenceHIV riskLower incidenceHigh riskPrevention strategiesSex partnersDrug useAn Exploratory Factor Analysis of a Brief Self-Report Scale to Detect Neurocognitive Impairment Among Participants Enrolled in Methadone Maintenance Therapy
Copenhaver M, Shrestha R, Wickersham JA, Weikum D, Altice FL. An Exploratory Factor Analysis of a Brief Self-Report Scale to Detect Neurocognitive Impairment Among Participants Enrolled in Methadone Maintenance Therapy. Journal Of Substance Use And Addiction Treatment 2016, 63: 61-65. PMID: 26879859, PMCID: PMC4775373, DOI: 10.1016/j.jsat.2016.01.002.Peer-Reviewed Original ResearchConceptsMethadone maintenance therapyNeuropsychological Impairment ScaleNeurocognitive impairmentMaintenance therapySex-related HIV risk behaviorsHIV risk behaviorsClinical care settingsNeuro-cognitive impairmentExploratory factor analysisCare settingsImpairment ScaleRisk behaviorsAddiction treatmentBrief self-report scaleImpairmentSelf-report measuresSelf-report scalesPatientsPrincipal axis factoringCognitive functioningTherapyFactor analysisOrthogonal varimax rotationPresent studyPotential utility
2015
A non-inferiority trial of an evidence-based secondary HIV prevention behavioral intervention compared to an adapted, abbreviated version: Rationale and intervention description
Shrestha R, Krishnan A, Altice FL, Copenhaver M. A non-inferiority trial of an evidence-based secondary HIV prevention behavioral intervention compared to an adapted, abbreviated version: Rationale and intervention description. Contemporary Clinical Trials 2015, 44: 95-102. PMID: 26253181, PMCID: PMC4744142, DOI: 10.1016/j.cct.2015.08.002.Peer-Reviewed Original ResearchEvidence-based interventionsHIV risk behaviorsHolistic Health Recovery ProgramSex-related HIV risk behaviorsRisk behaviorsClinical settingCurrent HIV prevention effortsReal-world clinical settingHIV prevention behavioral interventionFormal cost-effectiveness analysisAntiretroviral therapy adherenceNon-inferiority trialHIV prevention effortsAddiction treatment settingsCommon clinical settingsCost-effective relativeCost-effectiveness analysisAddiction treatment programsTherapy adherenceTarget HIVTrial designHIVIntervention DescriptionTreatment settingsUnmet need