2024
Comparing the brief Holistic Health for HIV (3H+) to the Holistic Health Recovery Program (HHRP+) among people with HIV and opioid use disorder: Results from a randomized, controlled non-inferiority trial
Zelenev A, Huedo-Medina T, Shrestha R, Mistler C, Altice F, Sibilio B, Copenhaver M. Comparing the brief Holistic Health for HIV (3H+) to the Holistic Health Recovery Program (HHRP+) among people with HIV and opioid use disorder: Results from a randomized, controlled non-inferiority trial. PLOS ONE 2024, 19: e0312165. PMID: 39509356, PMCID: PMC11542883, DOI: 10.1371/journal.pone.0312165.Peer-Reviewed Original ResearchConceptsHolistic Health Recovery ProgramEvidence-based interventionsHolistic healthHIV treatmentRisk behaviorsReduce HIV risk behaviorsDifference-in-differencesEnd-of-interventionControlled non-inferiority trialHIV Epidemic goalsDrug treatment settingsAttainment of viral suppressionNon-inferiority trialRecovery programViral suppressionHigh ART adherenceHIV risk behaviorsNon-inferiorityHHRP+ART adherenceBehavioral interventionsReal-world settingsNon-parametric bootstrappingCondom useOpioid-dependent peopleExamining the Accuracy of Self-Reported Antiretroviral Therapy Adherence Using a Visual Analog Scale Among Opioid-Dependent People Living with HIV
Ssenyonjo J, Li X, Shrestha R, Copenhaver M. Examining the Accuracy of Self-Reported Antiretroviral Therapy Adherence Using a Visual Analog Scale Among Opioid-Dependent People Living with HIV. AIDS And Behavior 2024, 1-6. PMID: 39500816, DOI: 10.1007/s10461-024-04526-5.Peer-Reviewed Original ResearchVisual analog scaleOpioid-dependent peopleMeasure ART adherenceMethadone maintenance programPharmacy refill dataART adherenceAnalog scaleRefill dataSelf-reported visual analog scaleOpioid-dependent personsAntiretroviral therapy adherenceInner-city methadone maintenance programSelf-reported adherenceRandomized controlled trialsAntiretroviral therapyViral suppressionPatient populationPromote adherenceVAS ratingsTherapy adherenceHIVAdherence dataRefill informationTime pointsPharmacy
2023
The Mediating Effect of Changes in Depression Symptoms on the Relationship between Health-Related Quality of Life and Alcohol Consumption: Findings from a Longitudinal Study among Men Living with HIV in India
Ha T, Shi H, Shrestha R, Gaikwad S, Joshi K, Padiyar R, Schensul S. The Mediating Effect of Changes in Depression Symptoms on the Relationship between Health-Related Quality of Life and Alcohol Consumption: Findings from a Longitudinal Study among Men Living with HIV in India. International Journal Of Environmental Research And Public Health 2023, 20: 5567. PMID: 37107849, PMCID: PMC10138320, DOI: 10.3390/ijerph20085567.Peer-Reviewed Original ResearchConceptsHealth-related qualityMale PLWHDepressive symptomsAlcohol useDepression symptomsAlcohol consumptionImproved health-related qualityLower health-related qualityMental healthAntiretroviral therapy adherenceQuality of lifeHeavy alcohol useART adherenceHIV infectionTherapy adherenceClinical trialsIntervention groupIntervention participantsPLWHLower alcohol useControl groupSymptomsHRQoLControl participantsDemographic characteristics
2019
HIV-Related Stigma, Motivation to Adhere to Antiretroviral Therapy, and Medication Adherence Among HIV-Positive Methadone-Maintained Patients
Shrestha R, Altice FL, Copenhaver MM. HIV-Related Stigma, Motivation to Adhere to Antiretroviral Therapy, and Medication Adherence Among HIV-Positive Methadone-Maintained Patients. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2019, 80: 166-173. PMID: 30383588, PMCID: PMC6331231, DOI: 10.1097/qai.0000000000001891.Peer-Reviewed Original ResearchConceptsOptimal ART adherenceAntiretroviral therapyMethadone-maintained patientsMethadone maintenance treatmentART adherenceMaintenance treatmentHIV treatment outcomesHIV-positive patientsOpioid agonist therapyMultivariable logistic regressionHIV risk behaviorsExplanatory pathwaysAgonist therapySuboptimal adherenceMedication adherenceHIV treatmentTreatment outcomesHIV stigmaPatientsLogistic regressionHIVPrevention initiativesTherapyAdherenceSignificant correlates
2018
Viral suppression among HIV-infected methadone-maintained patients: The role of ongoing injection drug use and adherence to antiretroviral therapy (ART)
Shrestha R, Copenhaver MM. Viral suppression among HIV-infected methadone-maintained patients: The role of ongoing injection drug use and adherence to antiretroviral therapy (ART). Addictive Behaviors 2018, 85: 88-93. PMID: 29879611, PMCID: PMC6337064, DOI: 10.1016/j.addbeh.2018.05.031.Peer-Reviewed Original ResearchConceptsMethadone maintenance therapyMethadone-maintained patientsOngoing injection drug useViral suppressionAntiretroviral therapyInjection drug useHIV risk behaviorsDrug useSelf-reported HIV risk behaviorsImproved virologic outcomesOptimal ART adherenceHigher CD4 countsSustained viral suppressionMultivariable logistic regressionVirologic outcomesCD4 countMaintenance therapyOptimal adherenceART adherenceHIV treatmentIndependent correlatesTreatment challengesRisk populationsPatientsHIV
2017
An explanatory factor analysis of a brief self-report scale to detect neurocognitive impairment among HIV-positive men who have sex with men and transgender women in Peru
Weikum D, Shrestha R, Ferro EG, Vagenas P, Copenhaver M, Spudich S, Alpert MD, Cabello R, Lama JR, Sanchez J, Altice FL. An explanatory factor analysis of a brief self-report scale to detect neurocognitive impairment among HIV-positive men who have sex with men and transgender women in Peru. AIDS Care 2017, 29: 1297-1301. PMID: 28449599, PMCID: PMC6337065, DOI: 10.1080/09540121.2017.1322681.Peer-Reviewed Original ResearchConceptsHIV-positive menNeuropsychological Impairment ScaleNeurocognitive impairmentTransgender womenAntiretroviral therapyHIV-positive MSMPoor clinical outcomeHIV risk behaviorsClinical care settingsHealth-related outcomesExploratory factor analysisART adherenceClinical outcomesPatient populationCare settingsImpairment ScaleRisk behaviorsImpairmentMenPrincipal axis factoringSelf-report scalesOrthogonal varimax rotationWomenBrief self-report scaleOutcomes
2016
Treatment Engagement Moderates the Effect of Neurocognitive Impairment on Antiretroviral Therapy Adherence in HIV-Infected Drug Users in Treatment
Shrestha R, Karki P, Huedo-Medina TB, Copenhaver M. Treatment Engagement Moderates the Effect of Neurocognitive Impairment on Antiretroviral Therapy Adherence in HIV-Infected Drug Users in Treatment. Journal Of The Association Of Nurses In AIDS Care 2016, 28: 85-94. PMID: 27769735, PMCID: PMC5183513, DOI: 10.1016/j.jana.2016.09.007.Peer-Reviewed Original Research