2024
Living in disadvantaged neighborhoods linked to less intervention for severe aortic stenosis
Ram C, Yousef S, Ma W, Vallabhajosyula I, Singh S, Agarwal R, Milewski R, Assi R, Patel P, Williams M, Geirsson A, Vallabhajosyula P. Living in disadvantaged neighborhoods linked to less intervention for severe aortic stenosis. Scientific Reports 2024, 14: 4952. PMID: 38418864, PMCID: PMC10902341, DOI: 10.1038/s41598-024-52660-w.Peer-Reviewed Original ResearchConceptsAortic valve replacementSevere aortic stenosisAfrican American raceArea Deprivation IndexAortic stenosisSevere ASArea deprivation index rankAortic valve replacement ratesAmerican raceAortic valve interventionPresentation of sepsisDiagnosis of ASADI groupValve replacementValve interventionDeprived neighbourhoodsAV interventionDisadvantaged neighborhoodsPatientsFemale genderDeprivation indexHigh-ADI groupLow-ADI groupStenosisRace
2022
Direct relationship between transvalvular velocity and cardiac dysfunction, morbidity, and mortality in patients with aortic stenosis
Yousef S, Amabile A, Ram C, Singh S, Agarwal R, Milewski R, Assi R, Patel P, Krane M, Geirsson A, Vallabhajosyula P. Direct relationship between transvalvular velocity and cardiac dysfunction, morbidity, and mortality in patients with aortic stenosis. Journal Of Cardiac Surgery 2022, 37: 5052-5062. PMID: 36378856, DOI: 10.1111/jocs.17199.Peer-Reviewed Original ResearchConceptsDegree of ASCardiac structural changesAortic stenosisSevere symptomatic aortic stenosisEnd-organ morbiditiesStructural cardiac changesSymptomatic aortic stenosisEnd-organ diseaseKaplan-Meier curvesRisk of mortalityTransvalvular flow velocityCochran-Armitage testCause mortalityPatient characteristicsCardiac changesCardiac dysfunctionPatient morbidityTransvalvular velocityCurrent guidelinesGroup BGroup ACaucasian raceHigh riskCox modelEarly interventionScreening Tool to Identify Patients with Advanced Aortic Valve Stenosis
Yousef S, Amabile A, Ram C, Huang H, Korutla V, Singh S, Agarwal R, Assi R, Milewski RK, Zhang Y, Patel PA, Krane M, Geirsson A, Vallabhajosyula P. Screening Tool to Identify Patients with Advanced Aortic Valve Stenosis. Journal Of Clinical Medicine 2022, 11: 4386. PMID: 35956007, PMCID: PMC9369431, DOI: 10.3390/jcm11154386.Peer-Reviewed Original ResearchAortic stenosisRisk prediction modelTertiary academic care centerAcademic care centerSevere aortic stenosisAortic valve stenosisBody mass indexCross-sectional analysisLogistic regression modelsLarge population cohortCardiovascular comorbiditiesEchocardiographic studyValve stenosisMass indexClinical burdenClinical variablesUnique patientsC-statisticCare centerMale genderPatient riskComorbidity variablesC-indexMultivariable modelInclusion criteriaOne and Five-Year Mortality Risk Prediction in Patients with Moderate and Severe Aortic Stenosis
Yousef S, Amabile A, Huang H, Agarwal R, Singh S, Ram C, Milewski RK, Assi R, Zhang Y, Krane M, Geirsson A, Vallabhajosyula P. One and Five-Year Mortality Risk Prediction in Patients with Moderate and Severe Aortic Stenosis. Journal Of Clinical Medicine 2022, 11: 2949. PMID: 35629075, PMCID: PMC9146915, DOI: 10.3390/jcm11102949.Peer-Reviewed Original ResearchSevere aortic stenosisAortic stenosisRisk prediction modelPatient characteristicsDegree of ASCox proportional hazards modelModerate aortic stenosisSevere AS patientsUnadjusted overall mortalityLow ejection fractionProportional hazards modelMortality risk predictionCardiac comorbiditiesEchocardiographic evidenceOnly patientsEjection fractionOverall mortalityAS patientsHigh morbidityComplex patientsC-statisticSingle institutionIndividualized riskRisk scoreHazards model
2021
CARDIAC STRUCTURAL CHANGES, END-ORGAN MORBIDITIES AND MORTALITY RELATE TO AORTIC STENOSIS IN A DEGREE-REPONSE RELATIONSHIP
Yousef S, Ram C, Singh S, Agarwal R, Milewski R, Assi R, Geirsson A, Vallabhajosyula P. CARDIAC STRUCTURAL CHANGES, END-ORGAN MORBIDITIES AND MORTALITY RELATE TO AORTIC STENOSIS IN A DEGREE-REPONSE RELATIONSHIP. Journal Of The American College Of Cardiology 2021, 77: 1750. DOI: 10.1016/s0735-1097(21)03106-5.Peer-Reviewed Original Research
2013
Symptomatic Obstruction of the Brachiocephalic and Left Subclavian Arteries Obscured by Aortic Stenosis
Hashim PW, Assi R, Grecu L, Dardik A. Symptomatic Obstruction of the Brachiocephalic and Left Subclavian Arteries Obscured by Aortic Stenosis. Annals Of Vascular Surgery 2013, 28: 737.e1-737.e5. PMID: 24368183, DOI: 10.1016/j.avsg.2013.04.030.Peer-Reviewed Case Reports and Technical NotesMeSH KeywordsAgedAngioplasty, BalloonAortic Valve StenosisArterial Occlusive DiseasesBrachiocephalic TrunkConstriction, PathologicDiagnostic ErrorsDizzinessFemaleHeart Valve Prosthesis ImplantationHemodynamicsHumansMuscle WeaknessPredictive Value of TestsStentsSubclavian Steal SyndromeSyncopeTreatment OutcomeUltrasonography, Doppler, ColorConceptsAortic stenosisLeft-sided weaknessAortic valve replacementArtery obstructionUncommon causeValve replacementSubclavian arterySymptomatic reliefCerebrovascular insufficiencyPatient's symptomsBrachiocephalic trunkClinical manifestationsSymptomatic obstructionVessel diseaseBrachiocephalic arteryDiagnostic challengeSubclavian obstructionUpper extremityStenosisObstructionBrachiocephalicArterySymptomsLightheadednessStenting