1998
Effects of Mental Stress on Left Ventricular and Peripheral Vascular Performance in Patients With Coronary Artery Disease
Jain D, Shaker M, Burg M, Wackers F, Soufer R, Zaret B. Effects of Mental Stress on Left Ventricular and Peripheral Vascular Performance in Patients With Coronary Artery Disease. Journal Of The American College Of Cardiology 1998, 31: 1314-1322. PMID: 9581726, DOI: 10.1016/s0735-1097(98)00092-8.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngiocardiographyCoronary DiseaseFemaleHemodynamicsHumansMaleMiddle AgedRadionuclide AngiographyStress, PsychologicalStroke VolumeVascular ResistanceVentricular Function, LeftConceptsLeft ventricular ejection fractionPeripheral vascular resistanceCoronary artery diseaseRate-pressure productStress-induced fallSystolic blood pressureArtery diseaseBlood pressureCardiac outputHeart rateMental stressGroup IHemodynamic variablesAnger recallGroup IIMental stressorsEnd-systolic ventricular elastanceMental stress-induced changesSemisupine bicycle exerciseGroup II patientsComparable increaseDiastolic blood pressureVentricular ejection fractionExercise-induced changesVascular resistance
1997
Effect of left ventricular function on the assessment of myocardial viability by technectium-99m sestamibi and correlation with positron emission tomography in patients with healed myocardial infarcts or stable angina pectoris, or both
Arrighi J, Ng C, Dey H, Wackers F, Soufer R. Effect of left ventricular function on the assessment of myocardial viability by technectium-99m sestamibi and correlation with positron emission tomography in patients with healed myocardial infarcts or stable angina pectoris, or both. The American Journal Of Cardiology 1997, 80: 1007-1013. PMID: 9352969, DOI: 10.1016/s0002-9149(97)00594-8.Peer-Reviewed Original ResearchConceptsCoronary artery diseasePositron emission tomographyLV dysfunctionArtery diseaseGroup 2Myocardial viabilityGroup 1Ejection fractionModerate coronary artery diseaseEmission tomographyModerate LV dysfunctionSevere LV dysfunctionStable angina pectorisLV ejection fractionGlobal LV dysfunctionAccuracy of technetiumSingle photon emissionSemiquantitative SPECTVentricular dysfunctionViability detectionAngina pectorisVentricular functionReduced perfusionSestamibi SPECTMyocardial infarct
1996
Comparison of Nifedipine GITS and Hydrochlorothiazide in the Management of Elderly Patients with Stage I–III Diastolic Hypertension*
Dey H, Soufer R, Hoffer P, Wackers F, Black H. Comparison of Nifedipine GITS and Hydrochlorothiazide in the Management of Elderly Patients with Stage I–III Diastolic Hypertension*. American Journal Of Hypertension 1996, 9: 598-606. PMID: 8783785, DOI: 10.1016/0895-7061(96)00168-9.Peer-Reviewed Original ResearchConceptsNifedipine gastrointestinal therapeutic systemGastrointestinal therapeutic systemDiastolic blood pressureBlood pressureDiastolic hypertensionStage IVentricular massCardiovascular functionTreatment differencesGoal diastolic blood pressureSignificant blood pressure reductionWeek placebo washout phasePlacebo washout phaseWeek maintenance phaseBlood pressure reductionGoal blood pressureDiastolic filling rateRenal blood flowGlomerular filtration rateLeft ventricular massBlood urea nitrogenShort-term therapyAdverse side effectsSignificant adverse effectsDiuretic therapy
1995
Left ventricular diastolic function: Physiology, methods of assessment, and clinical significance
Arrighi J, Soufer R. Left ventricular diastolic function: Physiology, methods of assessment, and clinical significance. Journal Of Nuclear Cardiology 1995, 2: 525-543. PMID: 9420835, DOI: 10.1016/s1071-3581(05)80045-5.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge FactorsAgedAnimalsCardiac CatheterizationCoronary DiseaseDiastoleEchocardiographyHeart FailureHumansMiddle AgedRadionuclide AngiographyVentricular Function, LeftConceptsDiastolic functionVentricular fillingHeart failureElevated pulmonary venous pressureNormal systolic ventricular functionSystolic ventricular functionNormal systolic functionCongestive heart failurePulmonary venous pressureCoronary artery diseaseCalcium channel blockersEarly ventricular fillingHealthy elderly subjectsMitral valve closureBeta blockersSystolic functionArtery diseaseCardiac catheterizationSuch patientsValvular diseaseVenous pressureVentricular functionOptimal therapyRadionuclide angiographyMyocardial complianceComparison of sestamibi single-photon emission computed tomography with positron emission tomography for estimating left ventricular myocarclial viability
Soufer R, Dey H, Ng C, Zaret B. Comparison of sestamibi single-photon emission computed tomography with positron emission tomography for estimating left ventricular myocarclial viability. The American Journal Of Cardiology 1995, 75: 1214-1219. PMID: 7778542, DOI: 10.1016/s0002-9149(99)80765-6.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCoronary DiseaseDeoxyglucoseFluorine RadioisotopesFluorodeoxyglucose F18HumansMaleMiddle AgedMyocardial ContractionRadionuclide VentriculographyStroke VolumeTechnetium Tc 99m SestamibiTomography, Emission-ComputedTomography, Emission-Computed, Single-PhotonVentricular Function, LeftConceptsPositron emission tomographySestamibi single-photon emissionSingle photon emissionCoronary artery diseaseMyocardial viabilityInferior wallArtery diseaseEmission tomographyFDG positron emission tomographySubset of patientsRegional ejection fractionDiscordant segmentsNonviable segmentsEjection fractionMethoxyisobutyl isonitrileRadionuclide ventriculographySestamibi protocolBlood flowMyocardial segmentsPatientsViable segmentsFluorodeoxyglucoseMIBITomographyDiseaseReverse redistribution on planar thallium scintigraphy: relationship to resting thallium uptake and long-term outcome
Dey H, Soufer R. Reverse redistribution on planar thallium scintigraphy: relationship to resting thallium uptake and long-term outcome. European Journal Of Nuclear Medicine And Molecular Imaging 1995, 22: 237-242. PMID: 7789397, DOI: 10.1007/bf01081519.Peer-Reviewed Original ResearchMeSH KeywordsAgedCoronary DiseaseFollow-Up StudiesHeartHumansPrognosisRadionuclide VentriculographyRegression AnalysisThallium RadioisotopesVentricular Function, LeftConceptsCoronary artery diseaseChronic coronary artery diseasePatient outcomesLogistic multiple regression analysisRR segmentsPlanar thallium scintigraphyLong-term outcomesRecent thrombolysisThallium reinjectionArtery diseaseThallium scintigraphyIndependent predictorsScintigraphic findingsPrognostic significanceMyocardial infarctionRedistribution imagesThallium uptakeThallium-201Physiologic basisScarred myocardiumMultiple regression analysisRegression analysisOutcomesThrombolysisInfarction
1993
Role of behavioral and psychological factors in mental stress-induced silent left ventricular dysfunction in coronary artery disease
Burg M, Jain D, Soufer R, Kerns R, Zaret B. Role of behavioral and psychological factors in mental stress-induced silent left ventricular dysfunction in coronary artery disease. Journal Of The American College Of Cardiology 1993, 22: 440-448. PMID: 8335813, DOI: 10.1016/0735-1097(93)90048-6.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCoronary DiseaseHumansMiddle AgedMultivariate AnalysisPsychological TestsStress, PsychologicalStroke VolumeType A PersonalityVentricular Function, LeftConceptsSilent left ventricular dysfunctionLeft ventricular dysfunctionCoronary artery diseaseVentricular dysfunctionArtery diseaseBlood pressureChronic stable coronary artery diseaseStable coronary artery diseaseStress thallium-201 imagingMental stressGroup I patientsSilent myocardial ischemiaThallium-201 imagingAbsence of symptomsSerial radionuclide ventriculographyStructured interviewsNonischemic groupEjection fractionI patientsPsychological factorsVentricular indexRadionuclide ventriculographyClinical indicesMyocardial ischemiaReversible defects
1992
Long-term outcome in patients with congestive heart failure and intact systolic left ventricular performance
Setaro J, Soufer R, Remetz M, Perlmutter R, Zaret B. Long-term outcome in patients with congestive heart failure and intact systolic left ventricular performance. The American Journal Of Cardiology 1992, 69: 1212-1216. PMID: 1575193, DOI: 10.1016/0002-9149(92)90938-u.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overFemaleFollow-Up StudiesHeart FailureHumansMaleMiddle AgedPulmonary EdemaStroke VolumeSurvival AnalysisTime FactorsVentricular Function, LeftConceptsCongestive heart failureLV systolic functionLV ejection fractionLong-term outcomesThird heart soundCardiovascular eventsCardiovascular mortalitySystolic functionEjection fractionHeart failurePulmonary edemaAverage LV ejection fractionRecurrent congestive heart failureNormal LV systolic functionLeft ventricular systolic performanceSame favorable prognosisLV diastolic dysfunctionAcute pulmonary edemaFuture cardiovascular eventsHypertensive heart diseaseVentricular systolic performanceCoronary artery diseaseHeart soundNoncardiovascular mortalityCardiovascular morbidityThe Radionuclide Assessment of Left Ventricular Diastolic Filling: Methodology and Clinical Significance
SOUFER R, DEY H. The Radionuclide Assessment of Left Ventricular Diastolic Filling: Methodology and Clinical Significance. Echocardiography 1992, 9: 339-348. PMID: 10149890, DOI: 10.1111/j.1540-8175.1992.tb00475.x.Peer-Reviewed Original ResearchMeSH KeywordsDiastoleEchocardiographyGated Blood-Pool ImagingHeart DiseasesHeart VentriclesHumansRadionuclide AngiographyVentricular Function, LeftConceptsDiastolic fillingLeft ventricular diastolic fillingDiastolic heart failureVentricular diastolic fillingHypertensive heart diseaseCoronary artery diseaseAppropriate clinical contextArtery diseaseHeart failureDiastolic performanceHeart diseasePathophysiological presentationHypertrophic cardiomyopathyClinical significanceNoninvasive indexRadionuclide assessmentClinical settingRadionuclide methodsClinical contextDiseaseCardiomyopathyRadionuclide measurementsLeft Ventricular Diastolic Function during Positive End-expiratory Pressure: Impact of Right Ventricular Ischemia and Ventricular Interaction
Schulman D, Biondi J, Zohgbi S, Cecchetti A, Zaret B, Soufer R. Left Ventricular Diastolic Function during Positive End-expiratory Pressure: Impact of Right Ventricular Ischemia and Ventricular Interaction. American Journal Of Respiratory And Critical Care Medicine 1992, 145: 515-521. PMID: 1546829, DOI: 10.1164/ajrccm/145.3.515.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCoronary CirculationCoronary DiseaseDiastoleDisease Models, AnimalDogsFemaleHemodynamicsMalePositive-Pressure RespirationVentricular Function, LeftVentricular Function, RightConceptsPositive end-expiratory pressureLeft ventricular end-diastolic pressure-volume relationEnd-expiratory pressureRCA occlusionEnd-diastolic volumeEnd-systolic volumeCardiac outputEjection fractionRight ventricularAddition of PEEPRight coronary artery occlusionEnd-diastolic pressure-volume relationRight ventricular ischemiaVentricular diastolic functionVentricular ejection fractionCoronary artery occlusionArtery occlusionAtrial pressureDiastolic functionPressure-volume relationVentricular ischemiaAnesthetized dogsVentricular interactionLV volumesRVEDV
1990
Usefulness of verapamil for congestive heart failure associated with abnormal left ventricular diastolic filling and normal left ventricular systolic performance
Setaro J, Zaret B, Schulman D, Black H, Soufer R. Usefulness of verapamil for congestive heart failure associated with abnormal left ventricular diastolic filling and normal left ventricular systolic performance. The American Journal Of Cardiology 1990, 66: 981-986. PMID: 2220622, DOI: 10.1016/0002-9149(90)90937-v.Peer-Reviewed Original ResearchConceptsCongestive heart failureNormal left ventricular systolic performanceLeft ventricular diastolic fillingLeft ventricular systolic performanceVentricular diastolic fillingVentricular systolic performanceDiastolic fillingBlood pressureHeart failureSystolic performanceAbnormal left ventricular diastolic fillingThallium-201 stress scintigraphyAbnormal diastolic fillingEDV/sHeart failure scoreSignificant valvular diseaseMean ejection fractionDiastolic blood pressureSystolic blood pressureLeft ventricular functionPeak filling rateOral verapamilExercise capacityPlacebo valuesSystolic function