2020
Lyme disease: diagnosis and treatment.
Schoen R. Lyme disease: diagnosis and treatment. Current Opinion In Rheumatology 2020, 32: 247-254. PMID: 32141956, DOI: 10.1097/bor.0000000000000698.Peer-Reviewed Original ResearchConceptsClinical manifestationsLyme arthritisAdjunctive laboratory testsAcute systemic illnessLyme diseaseDiagnosis of Lyme diseaseTreatment of Lyme diseaseOligo-arthritisUntreated patientsClinical featuresAntibiotic treatmentSystemic illnessRheumatic diseasesInflammatory arthritisTreatment approachesRheumatoid arthritisDiagnostic testsPatientsArthritisDiseaseManifestationsTreatmentVector-borne infectionsLaboratory testsLymeChallenges in the Diagnosis and Treatment of Lyme Disease
Schoen R. Challenges in the Diagnosis and Treatment of Lyme Disease. Current Rheumatology Reports 2020, 22: 3. PMID: 31912251, DOI: 10.1007/s11926-019-0857-2.Peer-Reviewed Original ResearchConceptsTreatment of Lyme diseaseClinical featuresCourse of oral antibiotic therapyOral antibiotic therapyLate-stage manifestationLate-stage diseaseLyme diseaseAntibiotic therapyCausative organismTreatment strategiesClinical expressionLyme arthritisImpact of Lyme diseaseDiagnosisDiseasePatientsTreatmentVector-borne illnessStrains of Borrelia burgdorferiLymeWell-characterizedMorbidityTherapyFindingsIt
2005
A comparison of two treatment regimens of ceftriaxone in late Lyme disease
Dattwyler R, Wormser G, Rush T, Finkel M, Schoen R, Grunwaldt E, Franklin M, Hilton E, Bryant G, Agger W, Maladorno D. A comparison of two treatment regimens of ceftriaxone in late Lyme disease. Wiener Klinische Wochenschrift 2005, 117: 393-397. PMID: 16053194, DOI: 10.1007/s00508-005-0361-8.Peer-Reviewed Original ResearchConceptsLate Lyme diseaseDays of therapyLyme diseaseSerologic criteriaClinical cure rateMulti-center studyEvaluable patientsOpen labelAdverse eventsClinical responseClinical subsetsTreatment failureTreatment regimensCure rateEntry criteriaObjective abnormalitiesSerologic resultsSerologic reactivityPatientsLast evaluationOptimal durationCeftriaxoneDiseaseTherapyBorrelia burgdorferi
1987
The clinical evolution of Lyme arthritis.
Steere A, Schoen R, Taylor E. The clinical evolution of Lyme arthritis. Annals Of Internal Medicine 1987, 107: 725-31. PMID: 3662285, DOI: 10.7326/0003-4819-107-5-725.Peer-Reviewed Original ResearchConceptsLyme arthritisClinical evolutionDisease onsetIntermittent attacksSubjective joint painErythema chronicum migransFrank arthritisChronic synovitisErosive diseaseJoint painAntibiotic therapyMusculoskeletal painJoint disabilityMean durationJoint abnormalitiesLarge jointsArthritisPatientsLyme diseaseSubsequent manifestationBrief episodesPainDiseaseEpisodesOnset