Exeporfinium chloride (XF-73) nasal gel dosed over 24 hours prior to surgery significantly reduced Staphylococcus aureus nasal carriage in cardiac surgery patients: Safety and efficacy results from a randomized placebo-controlled phase 2 study
Mangino J, Firstenberg M, Milewski R, Rhys-Williams W, Lees J, Dane A, Love W, Moreno J. Exeporfinium chloride (XF-73) nasal gel dosed over 24 hours prior to surgery significantly reduced Staphylococcus aureus nasal carriage in cardiac surgery patients: Safety and efficacy results from a randomized placebo-controlled phase 2 study. Infection Control And Hospital Epidemiology 2023, 44: 1171-1173. PMID: 36951472, PMCID: PMC10369221, DOI: 10.1017/ice.2023.17.Peer-Reviewed Original ResearchMeSH KeywordsAnti-Bacterial AgentsCardiac Surgical ProceduresCarrier StateChloridesHumansNoseStaphylococcal InfectionsStaphylococcus aureus