Unlocking the potential of miRNAs in detecting pulmonary tuberculosis: prospects and pitfalls
Arya R, Kumar S, Vinetz J, Kim J, Chaurasia R. Unlocking the potential of miRNAs in detecting pulmonary tuberculosis: prospects and pitfalls. Expert Reviews In Molecular Medicine 2024, 26: e32. PMID: 39639643, PMCID: PMC11629464, DOI: 10.1017/erm.2024.29.Peer-Reviewed Original ResearchConceptsDisease stageHIV co-infectionAnti-TB therapyPotential of miRNAsInfectious diseasesPulmonary TBPulmonary tuberculosisActive TBFalse-positive outcomesTB diagnosticsDisease progressionLack of specificityPrognostic signatureCo-infectionLethal infectious diseaseDeadliest infectious diseasesPoint-of-care testingTuberculosisDiagnostic biomarkersStandard protocolDiseaseBiomarkersGene expressionNon-invasiveRegulatory roleUrinary leptospiral sphingomyelinases as diagnostic markers of leptospirosis in dengue patients co-infected with leptospirosis
Chaurasia R, Kamaraju S, Thresiamma K, Jayaprakash C, Eapen C, Sritharan M. Urinary leptospiral sphingomyelinases as diagnostic markers of leptospirosis in dengue patients co-infected with leptospirosis. Diagnostic Microbiology And Infectious Disease 2024, 111: 116647. PMID: 39671978, DOI: 10.1016/j.diagmicrobio.2024.116647.Peer-Reviewed Original ResearchGroup IPatients co-infectedDiagnostic potentialAnti-leptospiral antibodiesLeptospiral antigensPrognostic potentialRenal damageUrinary excretionClinical evaluationGroup IIUrinary proteinGroup IIIPatientsHuman patientsDiagnostic markerCirculating proteinsEndemic regionsAntigenAntibodiesProteinuriaCoinfectionImmunoblot analysisSerumUrineNon-invasive