N-terminal transcriptional activation domain of LZIP comprises two LxxLL motifs and the Host Cell Factor-1 binding motif
Luciano R, Wilson A. N-terminal transcriptional activation domain of LZIP comprises two LxxLL motifs and the Host Cell Factor-1 binding motif. Proceedings Of The National Academy Of Sciences Of The United States Of America 2000, 97: 10757-10762. PMID: 10984507, PMCID: PMC27096, DOI: 10.1073/pnas.190062797.Peer-Reviewed Original ResearchConceptsTranscriptional activation domainHCF-1Activation domainLXXLL motifPotent transcriptional activation domainSequence-specific DNA-binding proteinsN-terminal beta-propeller domainTerminal transcriptional activation domainHost cell factor 1N-terminal 92 amino acidsTranscriptional activator VP16Multiprotein enhancer complexesDNA-binding proteinsProtein-protein interactionsImmediate early gene transcriptionBeta-propeller domainCell factor 1Nuclear hormone receptorsBZIP proteinsEnhancer complexTranscriptional coactivatorGene transcriptionBinding motifLZIPCell cycle