2017
Alloimmune Responses of Humanized Mice to Human Pluripotent Stem Cell Therapeutics
Kooreman NG, de Almeida PE, Stack JP, Nelakanti RV, Diecke S, Shao NY, Swijnenburg RJ, Sanchez-Freire V, Matsa E, Liu C, Connolly AJ, Hamming JF, Quax PHA, Brehm MA, Greiner DL, Shultz LD, Wu JC. Alloimmune Responses of Humanized Mice to Human Pluripotent Stem Cell Therapeutics. Cell Reports 2017, 20: 1978-1990. PMID: 28834758, PMCID: PMC5573767, DOI: 10.1016/j.celrep.2017.08.003.Peer-Reviewed Original ResearchConceptsHuman immune responseHumanized miceImmune cellsImmune responseStem cell allograftsInnate immune cellsAllogeneic stem cellsStem cellsMouse immune systemAlloimmune responseCell allograftsImmunodeficient miceMouse modelGraft persistenceImmune systemHuman lymphocytesMiceAllograftsStem cell therapeuticsCell therapeuticsPluripotent stem cellsEmbryonic stem cellsCellsAlloimmunityResponse
2015
Teratoma Formation: A Tool for Monitoring Pluripotency in Stem Cell Research
Nelakanti RV, Kooreman NG, Wu JC. Teratoma Formation: A Tool for Monitoring Pluripotency in Stem Cell Research. Current Protocols In Stem Cell Biology 2015, 32: 4a.8.1-4a.8.17. PMID: 25640819, PMCID: PMC4402211, DOI: 10.1002/9780470151808.sc04a08s32.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsEmbryonic germ layersInduced pluripotent stem cellsPluripotent stem cellsSpecific tissue typesStem cell researchGerm layersPluripotencyTeratoma formationTeratoma growthStem cellsTissue typesCell researchCell linesDetailed identificationMesodermCellsImmunodeficient miceProtocolGrowthLayerIdentification