2018
Hemodynamic Effects of Valve Asymmetry in Sapien 3 Transcatheter Aortic Valves.
Mangels DR, Siki M, Menon R, Bavaria J, Anwaruddin S, Giri J, Desai N, Szeto WY, Vallabhajosyula P, Herrmann HC. Hemodynamic Effects of Valve Asymmetry in Sapien 3 Transcatheter Aortic Valves. Journal Of Invasive Cardiology 2018, 30: 138-143. PMID: 29610444.Peer-Reviewed Original ResearchConceptsStructural valve deteriorationTranscatheter aortic valve replacementSAPIEN 3 valveParavalvular leakTransthoracic echocardiogramAortic insufficiencySAPIEN 3 transcatheter aortic valveAortic valve gradientSapien 3 prosthesisAortic valve replacementRetrospective cohort analysisTranscatheter aortic valveAI severityValve gradientAnnular calcificationHemodynamic effectsValve replacementValve deteriorationSmall prosthesisSingle institutionAortic valveAV gradientCohort analysisHigh incidenceSignificant differencesAssociation of Tricuspid Regurgitation With Transcatheter Aortic Valve Replacement Outcomes: A Report From The Society of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapy Registry
McCarthy FH, Vemulapalli S, Li Z, Thourani V, Matsouaka RA, Desai ND, Kirtane A, Anwaruddin S, Williams ML, Giri J, Vallabhajosyula P, Li RH, Herrmann HC, Bavaria JE, Szeto WY. Association of Tricuspid Regurgitation With Transcatheter Aortic Valve Replacement Outcomes: A Report From The Society of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapy Registry. The Annals Of Thoracic Surgery 2018, 105: 1121-1128. PMID: 29502934, DOI: 10.1016/j.athoracsur.2017.11.018.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve replacementHeart failure readmissionCardiology Transcatheter Valve Therapy RegistryThoracic Surgeons/American CollegeTranscatheter Valve Therapy RegistrySevere TRVentricular ejection fractionTricuspid regurgitationMild TRRisk patientsEjection fractionTR severityAmerican CollegeEffectiveness of TAVRInhospital major adverse cardiac eventsTranscatheter Aortic Valve Replacement OutcomesModerate TRMajor adverse cardiac eventsTricuspid regurgitation severityAdverse cardiac eventsAortic valve replacementHigh-risk patientsLow-risk patientsNumber of comorbiditiesIntensive care unit
2017
Management of coronary obstruction following transcatheter aortic valve replacement
Sultan I, Siki M, Wallen T, Szeto W, Vallabhajosyula P. Management of coronary obstruction following transcatheter aortic valve replacement. Journal Of Cardiac Surgery 2017, 32: 777-781. PMID: 29143378, DOI: 10.1111/jocs.13252.Peer-Reviewed Original ResearchMeSH KeywordsAged, 80 and overAortic Valve StenosisCoronary OcclusionFemaleHumansPostoperative ComplicationsTranscatheter Aortic Valve ReplacementConceptsTranscatheter aortic valve replacementAortic valve replacementValve replacementCoronary arterySelf-expanding transcatheter aortic valve replacementLeft coronary arteryTAVR casesCoronary ostiumCoronary obstructionHigh riskMortality rateComplicationsArteryOcclusionPreventionManagementReplacementOstiumObstructionMortalityIncidenceConscious Sedation Versus General Anesthesia for Transcatheter Aortic Valve Replacement
Hyman MC, Vemulapalli S, Szeto WY, Stebbins A, Patel PA, Matsouaka RA, Herrmann HC, Anwaruddin S, Kobayashi T, Desai ND, Vallabhajosyula P, McCarthy FH, Li R, Bavaria JE, Giri J. Conscious Sedation Versus General Anesthesia for Transcatheter Aortic Valve Replacement. Circulation 2017, 136: 2132-2140. PMID: 28864443, DOI: 10.1161/circulationaha.116.026656.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAnesthesia, GeneralAortic Valve StenosisComparative Effectiveness ResearchConscious SedationFemaleHospital MortalityHumansIntention to Treat AnalysisLength of StayMalePatient DischargePractice Patterns, Physicians'RegistriesRisk AssessmentRisk FactorsTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeUnited StatesConceptsTranscatheter aortic valve replacementAortic valve replacementConscious sedationIntensive care unitGeneral anesthesiaHospital lengthValve replacementProcedural successCare unitEnd-point analysisPercutaneous transfemoral transcatheter aortic valve replacementConscious Sedation Versus General AnesthesiaTransfemoral transcatheter aortic valve replacementCardiology Transcatheter Valve Therapy RegistryThoracic Surgeons/American CollegeDeath/stroke ratePacemaker/defibrillator implantationTranscatheter Valve Therapy RegistryInverse probabilityConscious sedation groupDeath/strokeTreatment-weighted adjustmentTreatment-weighted analysisLower procedural successComparative effectiveness analysisOutcomes of Elective Aortic Hemiarch Reconstruction for Aneurysmal Disease in the Elderly
Kilic A, Arnaoutakis GJ, Bavaria JE, Sultan I, Desai ND, Vallabhajosyula P, Williams ML, Milewski RK, Szeto WY. Outcomes of Elective Aortic Hemiarch Reconstruction for Aneurysmal Disease in the Elderly. The Annals Of Thoracic Surgery 2017, 104: 1522-1530. PMID: 28648536, DOI: 10.1016/j.athoracsur.2017.03.067.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAged, 80 and overAorta, ThoracicAortic Aneurysm, ThoracicBlood Vessel Prosthesis ImplantationCirculatory Arrest, Deep Hypothermia InducedCohort StudiesElective Surgical ProceduresFemaleGeriatric AssessmentHospital MortalityHumansMaleMiddle AgedPlastic Surgery ProceduresPostoperative CarePostoperative ComplicationsPrognosisPropensity ScoreRegistriesRetrospective StudiesRisk AssessmentSex FactorsSurvival AnalysisTreatment OutcomeConceptsModerate hypothermic circulatory arrestAntegrade cerebral perfusionHypothermic circulatory arrestHemiarch reconstructionElderly patientsAneurysmal diseaseOperative mortalityCerebral perfusionCirculatory arrestConcomitant aortic valve replacementRisk-adjusted operative mortalityCoronary artery bypassOperative mortality rateAortic valve replacementGreater comorbidity burdenLow operative mortalityOverall stroke rateSafe strategyIntensive care unitComorbidity burdenArtery bypassHospital stayRoot replacementValve replacementCare unit
2016
New Ventricular Septal Defects Following Balloon-Expandable Transcatheter Aortic Valve Replacement.
Rene AG, Jagasia D, Wickramasinghe SR, Desai N, Szeto W, Vallabhajosyula P, Li RH, Silvestry FE, Giri J, Jha S, Herrmann HC, Anwaruddin S. New Ventricular Septal Defects Following Balloon-Expandable Transcatheter Aortic Valve Replacement. Journal Of Invasive Cardiology 2016, 28: e59-65. PMID: 27342207.Peer-Reviewed Original ResearchMeSH KeywordsAged, 80 and overAortic ValveAortic Valve StenosisEchocardiographyFemaleHeart Septal Defects, VentricularHumansMaleOutcome and Process Assessment, Health CarePostoperative ComplicationsQuality of LifeReoperationRisk AssessmentRisk FactorsSeverity of Illness IndexTranscatheter Aortic Valve ReplacementConceptsTranscatheter aortic valve replacementLeft ventricular outflow tract calcificationSevere symptomatic aortic stenosisVentricular outflow tract calcificationSymptomatic aortic stenosisAortic valve replacementVentricular septal defectNew ventricular septal defectQuality of lifeInoperable patientsInfrequent complicationParavalvular regurgitationValve replacementAortic stenosisVascular injurySeptal defectPatientsComplicationsStudied populationRegurgitationStenosisInjuryStrokeCalcification
2015
Outcomes of transcatheter aortic valve replacement in patients with chronic liver disease
Shah AM, Ogbara J, Herrmann HC, Fox Z, Kadakia M, Anwaruddin S, Bavaria JE, Desai ND, Jagasia D, Szeto WY, Li RH, Vallabhajosyula P, Giri J. Outcomes of transcatheter aortic valve replacement in patients with chronic liver disease. Catheterization And Cardiovascular Interventions 2015, 86: 888-894. PMID: 25963625, DOI: 10.1002/ccd.25994.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic ValveAortic Valve StenosisBioprosthesisBiopsyCardiac CatheterizationChronic DiseaseFeasibility StudiesFemaleFemoral ArteryHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHospital MortalityHumansLiver DiseasesMaleMiddle AgedPatient SelectionRetrospective StudiesRisk AssessmentRisk FactorsSeverity of Illness IndexTime FactorsTreatment OutcomeConceptsTranscatheter aortic valve replacementChronic liver diseaseValve Academic Research ConsortiumAcute kidney injuryAortic valve replacementLiver diseaseLate deathsKidney injuryValve replacementUnknown causeTransapical (TA) TAVRRole of TAVRTA TAVRSevere symptomatic aortic valve stenosisModerate chronic liver diseaseSymptomatic aortic valve stenosisAdvanced liver diseaseMajor bleeding complicationsNon-cardiac causesOutcomes of patientsTransient ischemic attackAcademic Research ConsortiumHigh-risk surgeryAortic valve stenosisLong-term followOverestimation of Paravalvular Leak With Edwards SAPIEN 3 Transcatheter Aortic Valve Replacement
Kobayashi T, Giri J, Vallabhajosyula P, Herrmann HC, Jagasia DH. Overestimation of Paravalvular Leak With Edwards SAPIEN 3 Transcatheter Aortic Valve Replacement. JACC Cardiovascular Interventions 2015, 8: e69-e71. PMID: 25946455, DOI: 10.1016/j.jcin.2014.11.027.Peer-Reviewed Original ResearchAged, 80 and overAortic ValveAortic Valve InsufficiencyAortic Valve StenosisAortographyCardiac CatheterizationDiagnostic ErrorsEchocardiography, Doppler, ColorFemaleHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHumansPredictive Value of TestsProsthesis DesignReproducibility of ResultsSeverity of Illness IndexTomography, X-Ray ComputedTreatment Outcome
2014
Distal aortic reintervention after surgery for acute DeBakey type I or II aortic dissection: open versus endovascular repair†
Rylski B, Beyersdorf F, Desai ND, Euringer W, Siepe M, Kari FA, Vallabhajosyula P, Szeto WY, Milewski RK, Bavaria JE. Distal aortic reintervention after surgery for acute DeBakey type I or II aortic dissection: open versus endovascular repair†. European Journal Of Cardio-Thoracic Surgery 2014, 48: 258-263. PMID: 25527171, DOI: 10.1093/ejcts/ezu488.Peer-Reviewed Original ResearchConceptsDeBakey type IDistal reinterventionAortic reinterventionDissection repairEndovascular groupHospital mortalityAortic pathologyAcute aortic dissection repairAcute DeBakey type IType IAortic dissection repairDistal aortic pathologyDistal aortic reinterventionOpen repair patientsEndovascular patientsLate reinterventionSpinal ischaemiaAcute dissectionEndovascular repairAortic dissectionConsecutive patientsEndovascular approachSurgical repairTertiary centerMedian timeOutcomes of Surgery for Chronic Type A Aortic Dissection
Rylski B, Milewski RK, Bavaria JE, Branchetti E, Vallabhajosyula P, Szeto WY, Desai ND. Outcomes of Surgery for Chronic Type A Aortic Dissection. The Annals Of Thoracic Surgery 2014, 99: 88-93. PMID: 25442993, DOI: 10.1016/j.athoracsur.2014.07.032.Peer-Reviewed Original ResearchConceptsOutcome of surgeryChronic dissectionAortic dissectionChronic groupDissection patientsAortic tissueChronic Type A Aortic DissectionBicuspid aortic valve syndromeType A Aortic DissectionAcute dissection patientsChronic dissection patientsChronic Stanford typeNative ascending aortaA Aortic DissectionPrevious cardiac surgeryAortic root replacementMajority of patientsLong-term resultsHospital mortalityAcute typePrimary surgeryOverall survivalRoot replacementStanford typeCardiac surgeryEndovascular repair of the ascending aorta in patients at high risk for open repair
Vallabhajosyula P, Gottret JP, Bavaria JE, Desai ND, Szeto WY. Endovascular repair of the ascending aorta in patients at high risk for open repair. Journal Of Thoracic And Cardiovascular Surgery 2014, 149: s144-s150. PMID: 25218530, DOI: 10.1016/j.jtcvs.2014.07.063.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAneurysm, FalseAortic AneurysmAortic DissectionAortographyBlood Vessel ProsthesisBlood Vessel Prosthesis ImplantationComorbidityEndovascular ProceduresHumansLength of StayMaleMiddle AgedProsthesis DesignRetrospective StudiesRisk FactorsStentsTime FactorsTomography, X-Ray ComputedTreatment OutcomeYoung AdultConceptsEndovascular repairAortic pathologyHigh riskStent graft lengthOpen surgical treatmentThoracic aortic pathologyAmplatzer occluder deviceCommon carotid arteryCurrent endovascular technologyIntraoperative endoleaksMinor strokeProhibitive riskAortic dissectionOpen repairSurgical treatmentAortic accessOpen surgeryTechnical successZenith TX2Extensive comorbidityOccluder deviceIliac limbCarotid arteryEmergency basisEndovascular technologyLong-term results of aggressive hemiarch replacement in 534 patients with type A aortic dissection
Rylski B, Milewski RK, Bavaria JE, Vallabhajosyula P, Moser W, Szeto WY, Desai ND. Long-term results of aggressive hemiarch replacement in 534 patients with type A aortic dissection. Journal Of Thoracic And Cardiovascular Surgery 2014, 148: 2981-2985. PMID: 25112930, DOI: 10.1016/j.jtcvs.2014.05.093.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAgedAged, 80 and overAortic Aneurysm, ThoracicAortic DissectionBlood Vessel Prosthesis ImplantationFemaleHospital MortalityHumansKaplan-Meier EstimateLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioPostoperative ComplicationsReoperationRetrospective StudiesRisk FactorsTime FactorsTreatment OutcomeConceptsDeBakey type IDistal aortic reinterventionHemiarch replacementAcute typeAortic reinterventionAortic dissectionDeBakey type I dissectionAdverse aortic eventsType I dissectionAortic arch aneurysmLong-term resultsType IAortic wall tissueDistal reinterventionHospital mortalityAortic eventsReoperation rateTotal archArch aneurysmIndependent predictorsReinterventionStudy populationMarfan syndromePatientsLower mortalityFactors Associated With Vascular Complications in Patients Undergoing Balloon-Expandable Transfemoral Transcatheter Aortic Valve Replacement via Open Versus Percutaneous Approaches
Kadakia MB, Herrmann HC, Desai ND, Fox Z, Ogbara J, Anwaruddin S, Jagasia D, Bavaria JE, Szeto WY, Vallabhajosyula P, Li R, Menon R, Kobrin DM, Giri J. Factors Associated With Vascular Complications in Patients Undergoing Balloon-Expandable Transfemoral Transcatheter Aortic Valve Replacement via Open Versus Percutaneous Approaches. Circulation Cardiovascular Interventions 2014, 7: 570-576. PMID: 25027520, DOI: 10.1161/circinterventions.113.001030.Peer-Reviewed Original ResearchConceptsTransfemoral transcatheter aortic valve replacementTranscatheter aortic valve replacementAortic valve replacementVascular complicationsLength of stayValve replacementOpen surgicalPC groupMultivariable analysisArtery diameterValve Academic Research ConsortiumSheath outer diameterMajor vascular complicationsAcademic Research ConsortiumPropensity-matched analysisPostprocedural lengthPropensity matchingClinical outcomesSignificant morbidityFemale sexPercutaneous approachSimilar riskComplicationsOS groupStayCombined Transaortic Transcatheter Valve Replacement and Thoracic Endografting
Komlo CM, Vallabhajosyula P, Bavaria JE, Desai ND, Anwaruddin S, Giri JS, Herrmann HC, Szeto WY. Combined Transaortic Transcatheter Valve Replacement and Thoracic Endografting. The Annals Of Thoracic Surgery 2014, 97: 696-698. PMID: 24484814, DOI: 10.1016/j.athoracsur.2013.05.099.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve replacementThoracic aortic endovascular repairPercutaneous coronary interventionAortic stenosisValve replacementAortic endovascular repairSevere aortic stenosisAortic valve replacementCritical aortic stenosisCatheter-based treatmentThoracic aortic aneurysmTranscatheter valve replacementPartial sternotomy approachCatheter-based proceduresTAo accessCoronary interventionEndovascular repairTransaortic approachTransfemoral accessSternotomy approachAortic aneurysmThoracic endograftingFirst reportEndograftingStenosis
2012
Percutaneous Closure of a Left Ventricular Pseudoaneurysm After Sapien XT Transapical Transcatheter Aortic Valve Replacement
Bortnick AE, Gordon E, Gutsche J, Anwaruddin S, Szeto WY, Desai N, Vallabhajosyula P, Bavaria JE, Herrmann HC. Percutaneous Closure of a Left Ventricular Pseudoaneurysm After Sapien XT Transapical Transcatheter Aortic Valve Replacement. JACC Cardiovascular Interventions 2012, 5: e37-e38. PMID: 23257383, DOI: 10.1016/j.jcin.2012.08.014.Peer-Reviewed Original ResearchMeSH KeywordsAged, 80 and overAneurysm, FalseAortic Valve StenosisCardiac CatheterizationFemaleHeart AneurysmHeart Valve Prosthesis ImplantationHumans