2021
Chapter 10 Phosphatonins
Tebben P, Kumar R. Chapter 10 Phosphatonins. 2021, 215-233. DOI: 10.1016/b978-0-12-813073-5.00010-1.ChaptersSecreted frizzled-related protein 4X-linked hypophosphatemic ricketsPhosphorus balanceCell membrane integrityTumor-induced osteomalaciaFrizzled-related protein 4Fibroblast growth factor 23Matrix extracellular phosphoglycoproteinPhosphate homeostasisRenal phosphate reabsorptionPhosphate absorptionAbnormal phosphate homeostasisIntestinal phosphate absorptionMembrane integrityPhosphorusFibroblast growth factor 7Parathyroid hormonePhosphaturic peptidesHypophosphatemic ricketsPhosphate reabsorptionVitamin DRenal reabsorptionHypophosphatemic disordersNovel treatmentTumoral calcinosis
2018
Phosphaturic mesenchymal tumors: what an endocrinologist should know
Boland J, Tebben P, Folpe A. Phosphaturic mesenchymal tumors: what an endocrinologist should know. Journal Of Endocrinological Investigation 2018, 41: 1173-1184. PMID: 29446010, DOI: 10.1007/s40618-018-0849-5.Peer-Reviewed Original ResearchConceptsTumor-induced osteomalaciaPhosphaturic mesenchymal tumorMesenchymal tumorsCase of tumor-induced osteomalaciaRare cause of osteomalaciaPhosphaturic hormone fibroblast growth factor 23Recurrent genetic eventsHormone fibroblast growth factor 23Renal phosphate wastingFibroblast growth factor 23Autocrine/paracrine signaling loopTubular phosphate reabsorptionProgressive muscle weaknessProximal tubular phosphate reabsorptionConstellation of symptomsMolecular genetic aspectsBone painCalcitriol therapyCurative surgeryOncogenic osteomalaciaOffending tumorRare causeSurgical removalClinical featuresPrimary treatment
2017
Iron Replacement as A Therapeutic Approach For Renal Phosphate Wasting With Associated Iron Deficiency
Kumar A, Wermers R, Tebben P. Iron Replacement as A Therapeutic Approach For Renal Phosphate Wasting With Associated Iron Deficiency. AACE Clinical Case Reports 2017, 3: e260-e263. DOI: 10.4158/ep161330.cr.Peer-Reviewed Case Reports and Technical NotesAutosomal dominant hypophosphatemic ricketsTumor-induced osteomalaciaRenal phosphate wastingIron replacementIron deficiencyPhosphate wastingHypophosphatemic ricketsClinical improvementWeeks of iron therapyAutosomal recessive hypophosphatemic ricketsProgressive clinical improvementX-linked hypophosphatemic ricketsFibroblast growth factor 23Worsening muscle weaknessPotential treatment optionCalcitriol therapyHypophosphatemic osteomalaciaIron therapyDiffuse painFractional excretionTreatment optionsElevated FGF23Family historyProgressive weaknessFibroblast growth factor
2013
Tumor‐Induced Osteomalacia Resulting from Primary Cutaneous Phosphaturic Mesenchymal Tumor: A Case and Review of the Medical Literature
Gardner K, Shon W, Folpe A, Wieland C, Tebben P, Baum C. Tumor‐Induced Osteomalacia Resulting from Primary Cutaneous Phosphaturic Mesenchymal Tumor: A Case and Review of the Medical Literature. Journal Of Cutaneous Pathology 2013, 40: 780-784. PMID: 23962115, DOI: 10.1111/cup.12209.Peer-Reviewed Case Reports and Technical NotesConceptsPhosphaturic mesenchymal tumorTumor-induced osteomalaciaMesenchymal tumorsMedical literatureTumorOsteomalacia