2019
Automated expiratory ventilation assistance through a small endotracheal tube can improve venous return and cardiac output
Berlin DA, Manoach S, Oromendia C, Heerdt PM. Automated expiratory ventilation assistance through a small endotracheal tube can improve venous return and cardiac output. Intensive Care Medicine Experimental 2019, 7: 6. PMID: 30627962, PMCID: PMC6326914, DOI: 10.1186/s40635-018-0217-y.Peer-Reviewed Original ResearchConventional positive pressure ventilationExpiratory ventilation assistancePositive pressure ventilationSmall endotracheal tubeMedian cardiac outputVenous returnCardiac outputPressure ventilationEndotracheal tubeArterial pressureConventional ventilationVentilation assistanceLow central venous pressureCentral venous pressureSystemic arterial pressureEVA groupPEEP 0Venous pressureExpiratory pressureStroke volumeControl groupPorcine modelEffective ventilationVentilationHemorrhage
2017
Single-lung ventilation and oxidative stress
Heerdt PM, Stowe DF. Single-lung ventilation and oxidative stress. Current Opinion In Anaesthesiology 2017, 30: 42-49. PMID: 27783023, DOI: 10.1097/aco.0000000000000410.Peer-Reviewed Original ResearchConceptsSingle-lung ventilationOxidative stressRe-expanded lungHypoxic pulmonary vasoconstrictionRedistribution of bloodLocal tissue hypoxiaPostoperative disruptionPulmonary vasoconstrictionReperfusion responseAtelectatic lungTissue hypoxiaClinical dataReactive oxygenSystemic effectsOrgan functionLungNitrosative stressVentilationNitrogen speciesVasoconstriction