2014
Regulation of Protein Phosphatase 1I by Cdc25C-associated Kinase 1 (C-TAK1) and PFTAIRE Protein Kinase*
Platholi J, Federman A, Detert JA, Heerdt P, Hemmings HC. Regulation of Protein Phosphatase 1I by Cdc25C-associated Kinase 1 (C-TAK1) and PFTAIRE Protein Kinase*. Journal Of Biological Chemistry 2014, 289: 23893-23900. PMID: 25028520, PMCID: PMC4156073, DOI: 10.1074/jbc.m114.557744.Peer-Reviewed Original ResearchConceptsProtein phosphatase 1IC-TAK1Protein kinaseKinase 1GSK-3Protein phosphatase 1Phosphatase activityPP-1cThr-72Multisite phosphorylationActivating residuesPhosphatase 1Regulatory subunitSer-86Ser-71Subsequent phosphorylationMajor endogenous formsInhibitor 2PhosphorylationKinaseCdc25CEndogenous formPFTK1ResiduesActivation
2007
Differential regulation of protein phosphatase-1I by neurabin
Bullock SA, Platholi J, Gjyrezi A, Heerdt PM, Tung HY, Hemmings HC. Differential regulation of protein phosphatase-1I by neurabin. Biochemical And Biophysical Research Communications 2007, 358: 140-144. PMID: 17467665, PMCID: PMC1989152, DOI: 10.1016/j.bbrc.2007.04.076.Peer-Reviewed Original ResearchConceptsProtein phosphatase 1Phosphatase 1Protein phosphatase 1IProtein phosphataseActivation domainMultimeric complexesRegulatory subunitCatalytic subunitSubcellular localizationProtein kinaseSubstrate specificityRegulatory proteinsUnidentified proteinsNeurabinDifferential regulationNovel mechanismProteinSubunitsRegulationMajor formDistinct formsDependent formKinaseActinActivator