1999
A diffusion barrier maintains distribution of membrane proteins in polarized neurons
Winckler B, Forscher P, Mellman I. A diffusion barrier maintains distribution of membrane proteins in polarized neurons. Nature 1999, 397: 698-701. PMID: 10067893, DOI: 10.1038/17806.Peer-Reviewed Original ResearchMeSH KeywordsActinsAnimalsAxonsBiological TransportCell CompartmentationCell MembraneCell PolarityCells, CulturedCytoskeletonDiffusionDimethyl SulfoxideLeukocyte L1 Antigen ComplexMembrane GlycoproteinsMembrane ProteinsMicrospheresNeural Cell Adhesion MoleculesNeuronsRatsReceptors, AMPAThy-1 AntigensConceptsMembrane proteinsDiffusion barrierObvious physical barriersPlasma membrane domainsLateral mobilityOptical tweezersCell-cell contactMembrane domainsPresumptive domainPolarized neuronsPlasma membraneCytoskeletal componentsPolarized distributionF-actinDiffusion of proteinsDistinct domainsBasolateral surfaceMembrane markersProteinSpecialized domainsInitial segmentTight junctionsAsymmetric distributionPhysical barrierTweezers
1998
An emerging link between cytoskeletal dynamics and cell adhesion molecules in growth cone guidance
Suter D, Forscher P. An emerging link between cytoskeletal dynamics and cell adhesion molecules in growth cone guidance. Current Opinion In Neurobiology 1998, 8: 106-116. PMID: 9568398, DOI: 10.1016/s0959-4388(98)80014-7.Peer-Reviewed Original ResearchConceptsGrowth cone guidanceCell adhesion moleculeCell surface receptorsAdhesion moleculesCytoskeletal dynamicsCytoskeletal networkCytoskeletal proteinsExtracellular substratesSurface receptorsConcerted actionMolecular motorsNeuronal growthImportant mechanismRecent studiesModulation of couplingProtein