2014
Regeneration of Aplysia Bag Cell Neurons is Synergistically Enhanced by Substrate-Bound Hemolymph Proteins and Laminin
Hyland C, Dufresne ER, Forscher P. Regeneration of Aplysia Bag Cell Neurons is Synergistically Enhanced by Substrate-Bound Hemolymph Proteins and Laminin. Scientific Reports 2014, 4: 4617. PMID: 24722588, PMCID: PMC3983596, DOI: 10.1038/srep04617.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAplysiaCells, CulturedGrowth ConesHemocyaninsHemolymphLamininNeuritesNeuronsRegenerationSubstrate SpecificityConceptsBag cell neuronsHemolymph proteinsRespiratory protein hemocyaninAplysia bag cell neuronsProtein complexesFurther molecular characterizationAddition of hemolymphHigh molecular weight proteinsCell neuronsMolecular weight proteinsMolecular characterizationCellular targetsExtracellular matrixProteinNervous system repairNovel synergistic effectWeight proteinsLaminin substrateHumoral proteinsLamininPossible cooperationActive factorsMigration rateEndogenous factorsPotential relevance
2008
Coordination of Actin Filament and Microtubule Dynamics during Neurite Outgrowth
Schaefer AW, Schoonderwoert VT, Ji L, Mederios N, Danuser G, Forscher P. Coordination of Actin Filament and Microtubule Dynamics during Neurite Outgrowth. Developmental Cell 2008, 15: 146-162. PMID: 18606148, PMCID: PMC2595147, DOI: 10.1016/j.devcel.2008.05.003.Peer-Reviewed Original ResearchConceptsRetrograde actin network flowActin network flowNeurite outgrowthMyosin II contractilityRho-kinaseCell adhesion substratesCytoskeletal dynamicsMicrotubule behaviorAdhesion sitesAdhesion substrateMicrotubule dynamicsMyosin IIActin filamentsMolecular eventsGrowth responseMicrotubule movementKinaseNeuronal growthMicrotubulesOutgrowthGrowth cone neckGrowthOrganellesRegulationCascade
1994
Cytoskeletal reorganization underlying growth cone motility
Lin C, Thompson C, Forscher P. Cytoskeletal reorganization underlying growth cone motility. Current Opinion In Neurobiology 1994, 4: 640-647. PMID: 7849519, DOI: 10.1016/0959-4388(94)90004-3.Peer-Reviewed Original ResearchConceptsIndividual cytoskeletal elementsGrowth cone motilityCytoskeletal dynamicsCytoskeletal reorganizationIntracellular cytoskeletonExtracellular substratesCytoskeletal elementsLiving cellsCone motilityNeuronal migrationNeuronal outgrowthFunctional couplingRecent studiesCytoskeletonImportant componentRegulation