2001
Mode and Tempo of Tangential Cell Migration in the Cerebellar External Granular Layer
Komuro H, Yacubova E, Yacubova E, Rakic P. Mode and Tempo of Tangential Cell Migration in the Cerebellar External Granular Layer. Journal Of Neuroscience 2001, 21: 527-540. PMID: 11160432, PMCID: PMC6763794, DOI: 10.1523/jneurosci.21-02-00527.2001.Peer-Reviewed Original Research
1998
Distinct Modes of Neuronal Migration in Different Domains of Developing Cerebellar Cortex
Komuro H, Rakic P. Distinct Modes of Neuronal Migration in Different Domains of Developing Cerebellar Cortex. Journal Of Neuroscience 1998, 18: 1478-1490. PMID: 9454856, PMCID: PMC6792738, DOI: 10.1523/jneurosci.18-04-01478.1998.Peer-Reviewed Original ResearchConceptsGranule cellsInternal granular layerBergmann glial fibersGlial fibersMost granule cellsMossy fiber terminalsLocal environmental cuesPurkinje cell layerGranular layerAcute cerebellar slice preparationCerebellar slice preparationSynaptic contactsGranule cell movementSlice preparationFiber terminalsBergmann gliaCerebellar cortexPostmitotic neuronsNeuronal migrationNeuronsSomaCell layerCerebellar neurogenesisPresent studyDifferent cellular microenvironments
1996
Intracellular Ca2+ Fluctuations Modulate the Rate of Neuronal Migration
Komuro H, Rakic P. Intracellular Ca2+ Fluctuations Modulate the Rate of Neuronal Migration. Neuron 1996, 17: 275-285. PMID: 8780651, DOI: 10.1016/s0896-6273(00)80159-2.Peer-Reviewed Original Research
1995
Dynamics of granule cell migration: a confocal microscopic study in acute cerebellar slice preparations
Komuro H, Rakic P. Dynamics of granule cell migration: a confocal microscopic study in acute cerebellar slice preparations. Journal Of Neuroscience 1995, 15: 1110-1120. PMID: 7869087, PMCID: PMC6577849, DOI: 10.1523/jneurosci.15-02-01110.1995.Peer-Reviewed Original ResearchConceptsCell movementCell migrationPlasma membraneShort stationary phaseCerebellar slice preparationGranule cell migrationMolecular mechanismsMembrane flowConfocal microscopic studiesIndividual cellsNeuronal migrationConfocal microscopyCytological aspectsDil crystalsCellsMembraneBergmann glial fibersGranule cellsMigrationMicrons/hrOld micePostnatal lifeConsiderable variationAcute cerebellar slice preparationStationary phase
1993
Low-affinity p75 nerve growth factor receptor expression in the embryonic monkey telencephalon: Timing and localization in diverse cellular elements
Meinecke D, Rakic P. Low-affinity p75 nerve growth factor receptor expression in the embryonic monkey telencephalon: Timing and localization in diverse cellular elements. Neuroscience 1993, 54: 105-116. PMID: 8515837, DOI: 10.1016/0306-4522(93)90386-t.Peer-Reviewed Original ResearchConceptsDiverse cellular elementsNerve growth factor receptorGrowth factor receptorCerebral cortexCellular elementsFactor receptorAxonal processesNerve growth factor receptor expressionLow-affinity nerve growth factor receptorGrowth factorEmbryonic day 45Transient subplate neuronsGrowth factor receptor expressionFactor receptor expressionOnset of neurogenesisNerve growth factorHuman nerve growth factor receptorGrowth factor familyMonkey telencephalonSubplate neuronsSubplate zoneReceptor expressionFetal brainActive neurogenesisNeuronal proliferation
1992
Selective Role of N-Type Calcium Channels in Neuronal Migration
Komuro H, Rakic P. Selective Role of N-Type Calcium Channels in Neuronal Migration. Science 1992, 257: 806-809. PMID: 1323145, DOI: 10.1126/science.1323145.Peer-Reviewed Original ResearchConceptsN-type calcium channelsCalcium channelsNeuronal migrationT-type calcium channelsCerebellar slice preparationGranule cell migrationImmature neuronsSelective blockadeSlice preparationPostmitotic granule cellsAdult brainGranule cellsSynaptic circuitsNeurotransmitter releasePotassium channelsPlasmalemmal surfaceIncubation mediumCell migrationSelective roleLaser scanning confocal microscopeScanning confocal microscopeBlockadeSpecific developmental roleNeuronsBrain
1984
Cytodifferentiation and synaptogenesis in the neostriatum of fetal and neonatal rhesus monkeys
Brand S, Rakic P. Cytodifferentiation and synaptogenesis in the neostriatum of fetal and neonatal rhesus monkeys. Brain Structure And Function 1984, 169: 21-34. PMID: 6721218, DOI: 10.1007/bf00300583.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCaudate NucleusCell DifferentiationMacacaMacaca mulattaMicroscopy, ElectronPutamenSynapsesTime FactorsConceptsSynaptic densityDendritic shaftsFetal monthAsymmetric synapsesRhesus monkeysPostnatal rhesus monkeysNeonatal rhesus monkeysRound clear vesiclesFirst postnatal monthNeuronal cell bodiesShafts of dendritesGolgi impregnation methodEmbryonic day 60Axospinous synapsesSymmetric synapsesPresynaptic profilesPleomorphic vesiclesGlial cellsPostnatal monthAxonal profilesCaudate nucleusDendritic processesPostnatal developmentClear vesiclesCell bodies
1981
The prenatal development of the pulvinar in the monkey: 3H-thymidine autoradiographic and morphometric analyses
Ogren M, Rakic P. The prenatal development of the pulvinar in the monkey: 3H-thymidine autoradiographic and morphometric analyses. Brain Structure And Function 1981, 162: 1-20. PMID: 7283168, DOI: 10.1007/bf00318090.Peer-Reviewed Original ResearchConceptsPulvinar neuronsSubpopulation of neuronsAdjacent thalamic nucleiThirds of gestationMorphometric analysisSite of originSeries of animalsLateral pulvinarAfferent inputMedial pulvinarThalamic nucleiSubventricular zoneTelencephalic originThird ventricleLateral aspectCytoarchitectonic boundariesHuman pulvinarPulvinarNeuronsEmbryonic dayThymidine autoradiographyPrenatal developmentHistological sectionsMonkeysGestation
1979
A golgi study of radial glial cells in developing monkey telencephalon: Morphogenesis and transformation into astrocytes
Schmechel D, Rakic P. A golgi study of radial glial cells in developing monkey telencephalon: Morphogenesis and transformation into astrocytes. Brain Structure And Function 1979, 156: 115-152. PMID: 111580, DOI: 10.1007/bf00300010.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAstrocytesCell NucleusHaplorhiniMacacaMacaca mulattaNeurogliaTelencephalonTime FactorsConceptsRadial glial cellsGlial cellsCerebral wallSubventricular zoneOccipital lobeRadial fibersPial surfaceRadial glial fibersRapid Golgi methodMedial cerebral wallMonkey telencephalonCalcarine fissureCortical plateGolgi studyLateral ventricleProtoplasmic astrocytesLarge oval nucleiDay 365Ependymal cellsGlial fibersAstrocytesRhesus monkeysOlder ageDay 48Oval nuclei
1973
Kinetics of proliferation and latency between final cell division and onset of differentiation of cerebellar stellate and basket neurons
Rakic P. Kinetics of proliferation and latency between final cell division and onset of differentiation of cerebellar stellate and basket neurons. The Journal Of Comparative Neurology 1973, 147: 523-546. PMID: 4122708, DOI: 10.1002/cne.901470407.Peer-Reviewed Original Research
1968
Supravital DNA synthesis in the developing human and mouse brain.
RAKIC P, SIDMAN R. Supravital DNA synthesis in the developing human and mouse brain. Journal Of Neuropathology & Experimental Neurology 1968, 27: 246-76. PMID: 5646196, DOI: 10.1097/00005072-196804000-00006.Peer-Reviewed Original Research