1989
The Effect of Diazepam on Neonatal Seizure: In Vivo 31P and 1H NMR Study
Young R, Chen B, Petroff O, Gore J, Cowan B, Novotny E, Wong M, Zuckerman K. The Effect of Diazepam on Neonatal Seizure: In Vivo 31P and 1H NMR Study. Pediatric Research 1989, 25: 27-31. PMID: 2919113, DOI: 10.1203/00006450-198901000-00006.Peer-Reviewed Original ResearchConceptsBrain lactateBrain high-energy phosphatesArrest of seizuresFlurothyl-induced seizuresCerebral blood flowNormalization of EEGEffects of diazepamVivo 31P nuclear magnetic resonance spectroscopyHigh-energy phosphatesElectrographic seizuresNeonatal seizuresNeonatal dogsPostictal periodBrain pHBaseline valuesBlood flowBrain phosphocreatineMetabolic recoveryProlonged elevationSeizuresSustained increaseVivo 31PRapid returnDiazepamEnergy phosphates
1988
High‐Resolution Proton Magnetic Resonance Spectroscopy of Rabbit Brain: Regional Metabolite Levels and Postmortem Changes
Petroff O, Ogino T, Alger J. High‐Resolution Proton Magnetic Resonance Spectroscopy of Rabbit Brain: Regional Metabolite Levels and Postmortem Changes. Journal Of Neurochemistry 1988, 51: 163-171. PMID: 3379399, DOI: 10.1111/j.1471-4159.1988.tb04850.x.Peer-Reviewed Original ResearchConceptsN-acetylaspartateWhite matterRabbit cerebral cortexCerebral white matterProton magnetic resonance spectroscopyGamma-aminobutyric acidRegional metabolite levelsTotal creatine poolCardiac arrestCerebral cortexCerebral metabolitesRabbit brainMagnetic resonance spectroscopyCreatine poolMetabolite levelsReference standardPostmortem changesCortexResonance spectroscopy