1989
High-field proton magnetic resonance spectroscopy of human cerebrum obtained during surgery for epilepsy.
Petroff O, Spencer D, Alger J, Prichard J. High-field proton magnetic resonance spectroscopy of human cerebrum obtained during surgery for epilepsy. Neurology 1989, 39: 1197-202. PMID: 2771071, DOI: 10.1212/wnl.39.9.1197.Peer-Reviewed Original ResearchConceptsProton magnetic resonance spectroscopyGamma-aminobutyric acidWhite matterTemporal lobe cortexHuman cerebrumHigh-field proton magnetic resonance spectroscopyBeta-hydroxybutyric acidConcentrations of creatineRefractory epilepsyN-acetylaspartateTemporal lobeMagnetic resonance spectroscopyPerchloric acid extractsSignificant differencesSurgeryEpilepsyCerebrumCreatineAcid extractsResonance spectroscopy
1986
Combined 1H and 31P nuclear magnetic resonance spectroscopic studies of bicuculline‐induced seizures in vivo
Petroff O, Prichard J, Ogino T, Avison M, Alger J, Shulman R. Combined 1H and 31P nuclear magnetic resonance spectroscopic studies of bicuculline‐induced seizures in vivo. Annals Of Neurology 1986, 20: 185-193. PMID: 3752964, DOI: 10.1002/ana.410200203.Peer-Reviewed Original ResearchConceptsBicuculline-induced seizuresCerebral intracellular pHArterial blood pressureCerebral lactate levelsIntracellular pHLactate elevationProlonged seizuresBlood pressureParalyzed rabbitsLactate levelsHeart rateSeizuresLactate concentrationComplete recoverySigns of recoveryElectroencephalogramHoursCerebrumMagnetic resonance spectroscopic studiesBrain