Nicholas Christakis, MD, MPH, PhD
Sterling Professor of Social and Natural ScienceCards
About
Research
Publications
2024
Antidepressant use in spatial social networks
Lengyel B, Tóth G, Christakis N, Bíró A. Antidepressant use in spatial social networks. Science Advances 2024, 10: eadr0302. PMID: 39642229, PMCID: PMC11623294, DOI: 10.1126/sciadv.adr0302.Peer-Reviewed Original ResearchConceptsAntidepressant useSpatial social networksSocial networksAssociated with depression treatmentSmall-town residentsCohesiveness of social networksDiversity of social networksCohesive social networksMental health careDepression treatmentMental well-beingLocal communitiesMental healthEmpirical workWell-beingDistant communitiesDiverse networksHealth careLocal accessDistant placesCommunityIndividualsAntidepressantsYoung individualsTiesBringing leaders of network subgroups closer together does not facilitate consensus
Jones M, Christakis N. Bringing leaders of network subgroups closer together does not facilitate consensus. Scientific Reports 2024, 14: 30183. PMID: 39632953, PMCID: PMC11618600, DOI: 10.1038/s41598-024-81636-z.Peer-Reviewed Original ResearchGut microbiome strain-sharing within isolated village social networks
Beghini F, Pullman J, Alexander M, Shridhar S, Prinster D, Singh A, Matute Juárez R, Airoldi E, Brito I, Christakis N. Gut microbiome strain-sharing within isolated village social networks. Nature 2024, 637: 167-175. PMID: 39567691, PMCID: PMC11666459, DOI: 10.1038/s41586-024-08222-1.Peer-Reviewed Original ResearchVillage social networksClusters of speciesMicrobiome sequencing dataGut microbiome compositionStrain-level dataMicrobiome biologySequence dataSpecies-levelSocial networksMicrobial sharingPhenotypic impactMicrobiome compositionMicrobiomeSocial network mapsCo-villagersSocial nicheExtended social environmentPeripheral peopleGutSocial connectionsSocial environmentFace-to-face social networksClusters of peopleRelationship typesVillageEnvironmental, socioeconomic, and health factors associated with gut microbiome species and strains in isolated Honduras villages
Shridhar S, Beghini F, Alexander M, Singh A, Juárez R, Brito I, Christakis N. Environmental, socioeconomic, and health factors associated with gut microbiome species and strains in isolated Honduras villages. Cell Reports 2024, 43: 114442. PMID: 38968070, PMCID: PMC11290354, DOI: 10.1016/j.celrep.2024.114442.Peer-Reviewed Original ResearchGut microbiomeGut microbiome speciesSpecies-level profilingSequenced microbiomesMetagenomic dataMicrobiome speciesHost phenotypeBacterial speciesHuman phenotypesMesoamerican highlandsSeveral speciesGutSpeciesMicrobiomePhenotypeAssociated with body mass indexCommunity-based cohortBody mass indexConsistent with previous findingsSocioeconomic factorsIsolated villagesHousehold wealthMass indexHostStrainSimple autonomous agents can enhance creative semantic discovery by human groups
Ueshima A, Jones M, Christakis N. Simple autonomous agents can enhance creative semantic discovery by human groups. Nature Communications 2024, 15: 5212. PMID: 38890368, PMCID: PMC11189566, DOI: 10.1038/s41467-024-49528-y.Peer-Reviewed Original ResearchThe structure and function of antagonistic ties in village social networks
Ghasemian A, Christakis N. The structure and function of antagonistic ties in village social networks. Proceedings Of The National Academy Of Sciences Of The United States Of America 2024, 121: e2401257121. PMID: 38889155, PMCID: PMC11214085, DOI: 10.1073/pnas.2401257121.Peer-Reviewed Original ResearchConceptsNegative tiesVillage social networksSocial networksFunction of social networksVillage networkAntagonistic tiesSmall-world effectSurvey wavesRural villagesTiesAntagonistic relationshipHuman social networksHuman groupsVillagePositive worldPositive connectionEmpirical dataHighest betweenness centralityNetwork bridgeDissemination of informationNetworkBetweenness centralityShorter average distanceNodesWorldMaternal and child health intervention to promote behaviour change: a population-level cluster-randomised controlled trial in Honduras
Oles W, Alexander M, Negron R, Nelson J, Iriarte E, Airoldi E, Christakis N, Forastiere L. Maternal and child health intervention to promote behaviour change: a population-level cluster-randomised controlled trial in Honduras. BMJ Open 2024, 14: e060784. PMID: 38858139, PMCID: PMC11168147, DOI: 10.1136/bmjopen-2022-060784.Peer-Reviewed Original ResearchConceptsCluster randomised controlled trialPrimary outcomeCounseling interventionChild health interventionsCommunity health workersProfessional care seekingBreast-feedingPromote behavior changeSecondary outcome measuresFacility birthsUmbilical cord careCare-seekingNewborn healthNewborn careHealth workersHealth facilitiesEndline surveyHealth interventionsEducational interventionChild healthCord careHome settingCaring behaviorsSecondary outcomesSustained educational interventionsInduction of social contagion for diverse outcomes in structured experiments in isolated villages
Airoldi E, Christakis N. Induction of social contagion for diverse outcomes in structured experiments in isolated villages. Science 2024, 384: eadi5147. PMID: 38696582, DOI: 10.1126/science.adi5147.Peer-Reviewed Original ResearchSystematic review of methods to discern antagonistic ties in social networks in community settings
de la Rosa A, Cortez K, Lu A, Valentin B, Ghasemian A, Christakis N. Systematic review of methods to discern antagonistic ties in social networks in community settings. Social Sciences & Humanities Open 2024, 10: 101039. DOI: 10.1016/j.ssaho.2024.101039.Peer-Reviewed Original ResearchCommunity settingsSystematic reviewMethodological systematic reviewSystematic review of methodsNewcastle-Ottawa ScaleWell-being outcomesPhysical/mental healthValidity of measuresStudy characteristicsNewcastle-OttawaPRISMA guidelinesImprove consensusHealthBlinded reviewersQuality assessmentMapping social networksFace-to-face relationshipsSocial networksGood qualityNegative tiesCommunityPhysical/mentalSetsAscertainmentPRISMA
2023
Emergence and collapse of reciprocity in semiautomatic driving coordination experiments with humans
Shirado H, Kasahara S, Christakis N. Emergence and collapse of reciprocity in semiautomatic driving coordination experiments with humans. Proceedings Of The National Academy Of Sciences Of The United States Of America 2023, 120: e2307804120. PMID: 38079552, PMCID: PMC10743379, DOI: 10.1073/pnas.2307804120.Peer-Reviewed Original ResearchConceptsMachine intelligenceNorm of reciprocitySocial reciprocityNormative commitmentSocial coordinationHuman altruismNegative social repercussionsOnline participantsSocial normsCollective outcomesIndividual safetyCoordination experimentsCoordination gameSocial repercussionsIntelligenceHuman agencyAssistance systemsReciprocityHuman groupsTacit understandingPeopleAssistive technologyCollective challengesCollective action problemsLab experiments
Academic Achievements & Community Involvement
News
News
- May 06, 2024
Christakis Is Elected to the National Academy of Sciences
- March 24, 2021
Teaching Medicine to Machines: Using AI and Machine Learning to Improve Health Care
- June 06, 2020
Fourth Virtual Dean's Workshop Highlights Mathematical Modeling as a Valuable COVID-19 Tool
- June 05, 2020Source: YaleNews
Yale App Hunala Aims to Be ‘Waze for Coronavirus’