Featured Publications
Analgesia for Gynecologic Oncologic Surgeries: A Narrative Review
Patel K, Shergill S, Vadivelu N, Rajput K. Analgesia for Gynecologic Oncologic Surgeries: A Narrative Review. Current Pain And Headache Reports 2022, 26: 1-13. PMID: 35118596, DOI: 10.1007/s11916-022-00998-z.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsHyperthermic intraperitoneal chemotherapyCytoreductive surgeryPain managementNarrative reviewOptimal perioperative pain managementGynecologic oncologic surgeryPerioperative analgesic planPostoperative pain managementPerioperative pain managementLocal anesthetic infiltrationInvasive cancer surgeryMultimodal analgesicsPreemptive analgesiaMultimodal analgesiaPostoperative painAnalgesic planAnesthetic infiltrationGynecologic malignanciesIntraperitoneal chemotherapyPerioperative periodSurgery protocolThoracic epiduralCancer surgeryChronic painNeuraxial techniquesEndometriosis Pain Management: a Review
Carlyle D, Khader T, Lam D, Vadivelu N, Shiwlochan D, Yonghee C. Endometriosis Pain Management: a Review. Current Pain And Headache Reports 2020, 24: 49. PMID: 32671581, DOI: 10.1007/s11916-020-00884-6.Peer-Reviewed Original ResearchConceptsSurgical managementGnRH agonists/antagonistsNonsteroidal anti-inflammatory drugsPain management optionsAnti-inflammatory drugsAgonists/antagonistsNerve ablationPresacral neurectomyMedical managementTreatment modalitiesAromatase inhibitorsChallenging diseaseSurgical techniqueReviewThe purposeNeurectomyExperimental pharmaceuticalsManagement optionsAblationHysterectomyOophorectomyEndometriosisRegimensResectionDanazolPatients
2014
Transvaginal cholecystectomy learning curve
Wood SG, Dai F, Dabu-Bondoc S, Mikhael H, Vadivelu N, Duffy A, Roberts KE. Transvaginal cholecystectomy learning curve. Surgical Endoscopy 2014, 29: 1837-1841. PMID: 25294548, DOI: 10.1007/s00464-014-3873-3.Peer-Reviewed Original ResearchConceptsOperative timeTransvaginal cholecystectomyTVC patientsAcademic centersAverage age 41Learning curveResultsSixty-one patientsLaparoscopic cholecystectomy patientsAverage operative timeFellowship-trained surgeonsCholecystectomy patientsFemale patientsLC patientsMean ageMethodsThis studyAge 41PatientsSecond quartileSurgical repertoireSame time periodThird quartileLack of exposureFellowship trainingQuartileInterested surgeonsPerioperative dilemma: challenges of the management of a patient on mega doses of morphine and methadone.
Kaye AD, Alian AA, Vadivelu N, Chung KS. Perioperative dilemma: challenges of the management of a patient on mega doses of morphine and methadone. Journal Of Opioid Management 2014, 10: 69-72. PMID: 24604572, DOI: 10.5055/jom.2014.0194.Peer-Reviewed Original ResearchConceptsOpioid-induced hyperalgesiaHigh dosesHigh-dose opioidsCancer-related painPresent case reportMega dosesOpioid requirementsOpioid managementMetastatic leiomyosarcomaAgonist clonidineCase reportPotent analgesicOpioidsPatientsSuccessful managementDosesPainMethadoneMorphineHyperalgesiaClonidineAnalgesicsLeiomyosarcomaManagementAntagonist
2013
Comparison of immediate postoperative pain after transvaginal versus traditional laparoscopic cholecystectomy
Wood SG, Dabu-Bondoc S, Dai F, Mikhael H, Vadivelu N, Roberts KE. Comparison of immediate postoperative pain after transvaginal versus traditional laparoscopic cholecystectomy. Surgical Endoscopy 2013, 28: 1141-1145. PMID: 24232050, DOI: 10.1007/s00464-013-3294-8.Peer-Reviewed Original ResearchConceptsPost-anesthesia care unitPostoperative opioid useLaparoscopic cholecystectomyLC patientsLC groupTVC patientsOpioid requirementsPain scoresPain medicationPostoperative painOpioid useFour-port laparoscopic cholecystectomyImmediate postoperative pain managementOperating roomImmediate postoperative painIntraoperative opioid requirementsPACU pain scoresTraditional laparoscopic cholecystectomyAverage pain scorePostoperative pain managementLess pain medicationAnesthesia care unitBody mass indexTerms of agePaucity of data
2012
Intravenous Dextrose Administration Reduces Postoperative Antiemetic Rescue Treatment Requirements and Postanesthesia Care Unit Length of Stay
Dabu-Bondoc S, Vadivelu N, Shimono C, English A, Kosarussavadi B, Dai F, Shelley K, Feinleib J. Intravenous Dextrose Administration Reduces Postoperative Antiemetic Rescue Treatment Requirements and Postanesthesia Care Unit Length of Stay. Anesthesia & Analgesia 2012, 117: 591-596. PMID: 22253268, DOI: 10.1213/ane.0b013e3182458f9e.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAmbulatory Surgical ProceduresAnesthesia, GeneralAntiemeticsCritical CareDouble-Blind MethodFemaleGlucoseGynecologic Surgical ProceduresHumansHysteroscopyInjections, IntravenousIntensive Care UnitsLaparoscopyLength of StayMiddle AgedPostoperative Nausea and VomitingSolutionsTreatment OutcomeYoung AdultConceptsPostanesthesia care unitRinger's lactate solutionDextrose administrationControl groupLactate solutionPostanesthesia care unit lengthDextrose 5Antiemetic rescue medicationIntravenous dextrose administrationPostoperative nausea scoresRate of PONVRescue antiemetic medicationRescue medication requirementsStandardized general anesthesiaPlacebo-controlled trialPostoperative hospital stayASA class ICommon postoperative complicationPONV managementPONV ratePONV scoresRescue medicationUnanticipated admissionAntiemetic medicationHospital stay
2011
Safety of spinal anesthesia in a patient with achondroplasia for cesarean section.
Mikhael H, Vadivelu N, Braveman F. Safety of spinal anesthesia in a patient with achondroplasia for cesarean section. Current Drug Safety 2011, 6: 130-1. PMID: 21375478, DOI: 10.2174/157488611795684668.Peer-Reviewed Original ResearchConceptsSpinal anesthesiaCesarean sectionLow-dose meperidineBupivacaine spinal anesthesiaLimited mouth openingCervical spine instabilityAdministration of anesthesiaObstetric patientsPotential complicationsLumbar scoliosisSpine instabilityDrug choiceVertebral anomaliesMouth openingAchondroplastic dwarfAnesthesiaPatientsCareful evaluationControversial reportsBony characteristicsAdministrationConsideration of riskSafetyParturientsComplications
2010
Safety of Local Anesthesia Combined with Monitored Intravenous Sedation for American Society of Anesthesiologists 3 and 4 Patients Undergoing Lower Limb–preservation Procedures
Vadivelu N, Gesquire M, Mitra S, Shelley K, Kodumudi G, Xia Y, Blume P. Safety of Local Anesthesia Combined with Monitored Intravenous Sedation for American Society of Anesthesiologists 3 and 4 Patients Undergoing Lower Limb–preservation Procedures. The Journal Of Foot & Ankle Surgery 2010, 49: 152-154. PMID: 20137984, DOI: 10.1053/j.jfas.2009.09.006.Peer-Reviewed Original ResearchConceptsMonitored intravenous sedationIntravenous sedationCardiac complicationsASA 3Ankle blockCardiac care unit admissionLimb-preservation proceduresCare unit admissionLimb salvage proceduresLimb preservation surgeryAmerican SocietyAnesthesiologists 3Pulmonary complicationsUnit admissionAnesthesiologists classificationPerioperative variablesPrognostic valueRetrospective studySalvage procedureLocal anesthesiaInvasive monitoringPatientsComplicationsSedationUseful option
2009
Hemispheric Synchronized Sounds and Perioperative Analgesic Requirements
Dabu-Bondoc S, Vadivelu N, Benson J, Perret D, Kain ZN. Hemispheric Synchronized Sounds and Perioperative Analgesic Requirements. Anesthesia & Analgesia 2009, 110: 208-210. PMID: 19861358, DOI: 10.1213/ane.0b013e3181bea424.Peer-Reviewed Original ResearchConceptsPerioperative analgesic requirementsAnalgesic requirementsGeneral anesthesiaTreatment groupsVisual analog scale scoreIntraoperative analgesic requirementsIntraoperative fentanyl consumptionPostoperative pain scoresAnalog scale scoreFentanyl consumptionPain scoresSurgical outpatientsScale scoreControl groupAnesthesiaMusic groupScoresGroupSubjectsVecuroniumOutpatientsPain Quality Assessment Scale: Practical Implications of Factor Analysis
Souzdalnitski D, Bolinske T, Vadivelu N. Pain Quality Assessment Scale: Practical Implications of Factor Analysis. The Clinical Journal Of Pain 2009, 25: 453. PMID: 19454882, DOI: 10.1097/ajp.0b013e318193cf50.Peer-Reviewed Original Research
2008
Article Commentary: Pain after Mastectomy and Breast Reconstruction
Vadivelu N, Schreck M, Lopez J, Kodumudi G, Narayan D. Article Commentary: Pain after Mastectomy and Breast Reconstruction. The American Surgeon 2008, 74: 285-296. PMID: 18453290, DOI: 10.1177/000313480807400402.Peer-Reviewed Original ResearchConceptsSentinel node biopsyBreast cancerBreast reconstructionNode biopsyEarly treatmentInvasive therapyAcute post-operative painAcute nociceptive painPost-mastectomy painChronic neuropathic painChronic pain statesPost-operative painBreast-Conserving TherapyBreast cancer surgeryNeuropathic painPostoperative painNociceptive painOperative painPain statesCancer surgeryChronic painPhantom painPainMastectomyTherapy
2007
Can the Shikani Optical Stylet facilitate intubation in simulated difficult direct laryngoscopy?
Young CF, Vadivelu N. Can the Shikani Optical Stylet facilitate intubation in simulated difficult direct laryngoscopy? Connecticut Medicine 2007, 71: 407-8. PMID: 17879863.Peer-Reviewed Original Research
2006
Prolonged post-dural puncture headache in a patient with a renal transplant.
Vadivelu N, Mikhael H, Gordon M, Vindhya M, Holt N. Prolonged post-dural puncture headache in a patient with a renal transplant. Connecticut Medicine 2006, 70: 13-4. PMID: 16479870.Peer-Reviewed Original ResearchConceptsPostdural puncture headachePuncture headachePost-dural puncture headachePossible pathophysiological mechanismsRenal transplantSevere hypertensionPostrenal transplantCerebral autoregulationPathophysiological mechanismsCerebrospinal fluid formationMild severityHeadachePatientsFluid formationTransplantSeverityProbable causeHypertensionInteresting caseImpairment
2005
Successful cesarean section performed with inadvertent subdural anesthesia.
Vadivelu N, Yusufali T, Braveman F. Successful cesarean section performed with inadvertent subdural anesthesia. Connecticut Medicine 2005, 69: 71-2. PMID: 15779602.Peer-Reviewed Original Research
2000
Ketamine-fentanyl-midazolam infusion for the control of symptoms in terminal life care
Berger J, Ryan A, Vadivelu N, Merriam P, Rever L, Harrison P. Ketamine-fentanyl-midazolam infusion for the control of symptoms in terminal life care. American Journal Of Hospice And Palliative Medicine® 2000, 17: 127-134. PMID: 11406957, DOI: 10.1177/104990910001700213.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAnalgesicsCognition DisordersDrug Therapy, CombinationFemaleFentanylHumansHypnotics and SedativesInfusions, IntravenousKetamineMaleMidazolamMiddle AgedNeoplasmsPainPain MeasurementPsychomotor AgitationReceptors, N-Methyl-D-AspartateRetrospective StudiesTerminal CareTreatment Outcome