Featured Publications
ERAS Protocol Options for Perioperative Pain Management of Substance Use Disorder in the Ambulatory Surgical Setting
Zwolinski N, Patel K, Vadivelu N, Kodumudi G, Kaye A. ERAS Protocol Options for Perioperative Pain Management of Substance Use Disorder in the Ambulatory Surgical Setting. Current Pain And Headache Reports 2023, 27: 65-79. PMID: 37079258, PMCID: PMC10116112, DOI: 10.1007/s11916-023-01108-3.Peer-Reviewed Original ResearchConceptsSubstance use disordersSubstance use disorder patientsAmbulatory patientsUse disordersDisorder patientsERAS protocolPerioperative pain managementAmbulatory surgery settingHospital quality metricsAmbulatory surgical settingAmbulatory surgery casesPerioperative protocolPain managementAdverse outcomesAmbulatory surgeryPharmacodynamic profileSurgery settingAmbulatory proceduresSurgery casesClinical dataEarly recoveryAbused substancesSurgical settingPatientsSubspecialty groupsAmbulatory Pain Management in the Pediatric Patient Population
Oliver JA, Oliver LA, Aggarwal N, Baldev K, Wood M, Makusha L, Vadivelu N, Lichtor L. Ambulatory Pain Management in the Pediatric Patient Population. Current Pain And Headache Reports 2022, 26: 15-23. PMID: 35129824, DOI: 10.1007/s11916-022-00999-y.Peer-Reviewed Original ResearchConceptsPain managementPostoperative painPediatric ambulatory surgical patientsPostoperative pain controlAmbulatory surgical patientsSevere postoperative painExtent of painPeripheral nerve blocksPediatric ambulatory surgeryPediatric patient populationNon-pharmacological techniquesRandomized control studyEvidence-based approachMultimodal analgesiaPain controlSurgical patientsNerve blockPediatric populationAmbulatory surgeryPatient populationMost centersControl studyPainScientific evidenceMultimodal approachAnalgesia for Gynecologic Oncologic Surgeries: A Narrative Review
Patel K, Shergill S, Vadivelu N, Rajput K. Analgesia for Gynecologic Oncologic Surgeries: A Narrative Review. Current Pain And Headache Reports 2022, 26: 1-13. PMID: 35118596, DOI: 10.1007/s11916-022-00998-z.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsHyperthermic intraperitoneal chemotherapyCytoreductive surgeryPain managementNarrative reviewOptimal perioperative pain managementGynecologic oncologic surgeryPerioperative analgesic planPostoperative pain managementPerioperative pain managementLocal anesthetic infiltrationInvasive cancer surgeryMultimodal analgesicsPreemptive analgesiaMultimodal analgesiaPostoperative painAnalgesic planAnesthetic infiltrationGynecologic malignanciesIntraperitoneal chemotherapyPerioperative periodSurgery protocolThoracic epiduralCancer surgeryChronic painNeuraxial techniquesUltrasound-Guided Neuraxial Anesthesia
Li J, Krishna R, Zhang Y, Lam D, Vadivelu N. Ultrasound-Guided Neuraxial Anesthesia. Current Pain And Headache Reports 2020, 24: 59. PMID: 32812182, DOI: 10.1007/s11916-020-00895-3.Peer-Reviewed Original ResearchConceptsNeuraxial anesthesiaHigher first-attempt success rateFirst-attempt success rateNon-obstetric patientsAcute pain managementAttempt success ratePurpose of ReviewTherePain managementRegional anesthesiaNeuraxial spacePatient safety implicationsVertebral levelAnesthesiaOverall efficacyRecent FindingsUltrasoundNeedle passPatient safetyCatheter visualizationUltrasound utilizationClinical accuracySuccess rateCommon typeClinical applicationUltrasoundPatientsAcute Pain Management of Chronic Pain Patients in Ambulatory Surgery Centers
Rajput K, Vadivelu N. Acute Pain Management of Chronic Pain Patients in Ambulatory Surgery Centers. Current Pain And Headache Reports 2021, 25: 1. PMID: 33443656, DOI: 10.1007/s11916-020-00922-3.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsPerioperative pain managementAmbulatory surgery centersNon-opioid analgesicsPain managementSurgery centersIntrathecal pain pumpOpioid-tolerant patientsPostoperative opioid requirementsAcute pain managementChronic opioid useProportion of patientsSubset of patientsChronic pain patientsSame-day admission patientsSpinal cord stimulatorPurpose of ReviewWithOpioid requirementsPostoperative opioidsMalignant painMultimodal analgesiaPerioperative painOpioid toleranceOpioid usePain specialistsPain patientsRecovery Room Protocols for Nursing in Ambulatory Surgery Centers (ASCs) and Hospital Outpatient Departments (HOPDs)
Zafar J, Vadivelu N, Rajput K, Fontanez P. Recovery Room Protocols for Nursing in Ambulatory Surgery Centers (ASCs) and Hospital Outpatient Departments (HOPDs). 2021, 355-367. DOI: 10.1007/978-3-030-55262-6_27.ChaptersHospital outpatient departmentsAmbulatory surgery centersQuality of carePostoperative nauseaAdverse cardiac eventsFast-track protocolPain management protocolPain assessment scalesEvidence-based guidelinesLength of stayHypothermia protocolUnplanned admissionsCardiac eventsNursing protocolNurse assessmentPain managementRecovery roomOutpatient departmentStandardization of practiceOutpatient surgerySurgery centersCommon causeAmbulatory settingMultidisciplinary teamAssessment Scale
2021
Pain Management in Former Addicts on Medication-Assisted Treatment (MAT) Program
Rajput K, Kodumudi G, Vadivelu N. Pain Management in Former Addicts on Medication-Assisted Treatment (MAT) Program. 2021, 309-325. DOI: 10.1007/978-3-030-55262-6_23.ChaptersMedication-assisted treatmentOpiate addictionPerioperative pain management strategiesAdequate pain reliefPain management strategiesFraction of patientsPharmacologic risk factorsRisk of withdrawalMechanism of actionOpioid prescriptionsPain reliefPain managementPerioperative concernsAmbulatory surgeryDischarge planningRisk factorsOpioid epidemicHeroin abuseGeneral populationDrug AdministrationTreatment programPatientsDrugsFormer addictsTreatment
2016
Efficacy and Safety of Nonopioid Analgesics in Perioperative Pain Control.
Thomas DA, West M, Legler A, Maslin B, Kim RK, Vadivelu N. Efficacy and Safety of Nonopioid Analgesics in Perioperative Pain Control. Current Drug Safety 2016, 11: 196-205. PMID: 27113953, DOI: 10.2174/1574886311666160426130444.Peer-Reviewed Original ResearchConceptsPain controlNonopioid analgesicsSide effectsContemporary pain managementOptimum pain controlPerioperative pain controlAcute postoperative painPostoperative pain controlMultiple side effectsNonopioid medicationsPostoperative painTolerant patientsPain managementSafety profileAnalgesicsRecent dataComorbiditiesMedicationsOpioidsPainPatientsSurgeryMainstayControl
2014
Practical guide to the management of acute and chronic pain in the presence of drug tolerance for the healthcare practitioner.
Vadivelu N, Singh-Gill H, Kodumudi G, Kaye AJ, Urman RD, Kaye AD. Practical guide to the management of acute and chronic pain in the presence of drug tolerance for the healthcare practitioner. Ochsner Journal 2014, 14: 426-33. PMID: 25249810, PMCID: PMC4171802.Peer-Reviewed Original ResearchPain managementDrug toleranceMultidisciplinary pain managementChronic pain statesMethadone maintenance programPain statesSupportive carePatient's painChronic painMedication diversionSubstance disordersUrine testingDrug interactionsDetailed historyPatientsPainPsychiatric conditionsTimely interventionPatient's addictionPrescription drugsSafe outcomeDrug abuseAddictive disordersHealthcare practitionersMedical observationAvailability and utilization of opioids for pain management: global issues.
Manjiani D, Paul DB, Kunnumpurath S, Kaye AD, Vadivelu N. Availability and utilization of opioids for pain management: global issues. Ochsner Journal 2014, 14: 208-15. PMID: 24940131, PMCID: PMC4052588.Peer-Reviewed Original ResearchPain managementHealth statusChronic opiate therapyIntractable painful conditionsPathophysiology of painUtilization of opioidsEffective pain reliefEffective pain managementPalliative care populationChronic pain managementAbnormal sleep patternsDaily living activitiesIndividual health statusOpiate therapyOpioid agentsPain reliefDiabetes mellitusOpioid deliveryChronic painCare populationChronic sufferersPain educationPainful conditionsChronic conditionsHeart disease
2012
Acute Pain in Undergraduate Medical Education: An Unfinished Chapter!
Vadivelu N, Mitra S, Hines R, Elia M, Rosenquist RW. Acute Pain in Undergraduate Medical Education: An Unfinished Chapter! Pain Practice 2012, 12: 663-671. PMID: 22712557, DOI: 10.1111/j.1533-2500.2012.00580.x.Peer-Reviewed Original ResearchConceptsUndergraduate medical educationMedical school curriculumAcute pain diagnosisSchool curriculumEducational institutionsAcute painSignificant patient sufferingMedical educationMedical schoolsAdequate instructionHealth educatorsEducationPain educationCompassionate approachAcute pain syndromePain management specialistsRisk of chronicityAcute pain managementUnfinished chapterGlobal healthcare problemPain syndromeHealthcare imperativePain managementPain diagnosisIntegral part
2010
Buprenorphine in Postoperative Pain Management
Vadivelu N, Anwar M. Buprenorphine in Postoperative Pain Management. Anesthesiology Clinics 2010, 28: 601-609. PMID: 21074740, DOI: 10.1016/j.anclin.2010.08.015.Peer-Reviewed Original ResearchBuprenorphine: intravenous neuraxial and transdermal applications
Vadivelu N. Buprenorphine: intravenous neuraxial and transdermal applications. 2010, 157-160. DOI: 10.1017/cbo9780511841378.035.ChaptersPain managementAvailable pain medicationsAdjuvant medicationsNeuraxial opioidsPain medicationPain reliefAdverse eventsOpioid analgesicsPain processingMuscle relaxantsPharmacologic principlesNMDA antagonistsLocal anestheticsAnalgesicsCommon dosesClinical settingClinical useParticular drugTransdermal applicationMedicationsCliniciansDrugsAnalgesiaContraindicationsOpioids
2009
Pain Pathways and Acute Pain Processing
McQuay H, Vadivelu N, Whitney C, Sinatra R. Pain Pathways and Acute Pain Processing. 2009, 3-20. DOI: 10.1017/cbo9780511576706.003.ChaptersPain pathwaysPain managementAcute pain managementPatient-controlled analgesiaAcute pain processingRole of anesthesiologistsAnalgesic optionsPain serviceAcute painSevere painChronic painPain assessmentPain processingTherapeutic guidelinesOptimal carePainAnalgesiaPatientsChronicityPathophysiologyOptionsAnesthesiologistsCliniciansPathwayIncidence