2022
IncobotulinimtoxinA (Xeomin) for the treatment of adductor laryngeal dystonia: A prospective, open-label clinical trial
Kohli N, Lerner M, Rashty J, Kirke D, Stewart T, Blitzer A. IncobotulinimtoxinA (Xeomin) for the treatment of adductor laryngeal dystonia: A prospective, open-label clinical trial. American Journal Of Otolaryngology 2022, 43: 103613. PMID: 36055061, DOI: 10.1016/j.amjoto.2022.103613.Peer-Reviewed Original ResearchConceptsAdductor spasmodic dysphoniaSpasmodic dysphoniaOpen-label clinical trialProspective open-label trialAdductor laryngeal dystoniaOpen-label trialFirst-line treatmentVoice Handicap Index-10Side effect profileTransient side effectsNormal functionVHI-10 scoresIncobotulinumtoxinA injectionsEffect profileLine treatmentSystemic diseaseTA muscleBotulinum toxinClinical trialsLaryngeal dystoniaNursing womenThyroarytenoid muscleInjection sessionsExclusion criteriaSide effects
2021
Safety considerations for esophageal dilation by anesthetic type: A systematic review
Lerner MZ, Bourdillon AT, Dai F, Brackett A, Kohli N. Safety considerations for esophageal dilation by anesthetic type: A systematic review. American Journal Of Otolaryngology 2021, 42: 103128. PMID: 34216877, DOI: 10.1016/j.amjoto.2021.103128.Peer-Reviewed Original ResearchConceptsEsophageal dilationOffice-based techniqueSystematic reviewDerSimonian-Laird random-effects modelType of anesthesiaSmall case seriesOffice-based proceduresFull-text studiesUse of stentsRandom-effects modelComprehensive literature searchInverse variance weightingAdverse eventsAnesthetic typeCase seriesIntravenous sedationGeneral anesthesiaHigh morbidityAnesthesia techniquesLocal anesthesiaEmbase databasesExclusion criteriaEquivalent safetyPRISMA guidelinesRare disease
2017
IncobotulinumtoxinA Injection for Temporomandibular Joint Disorder
Patel AA, Lerner MZ, Blitzer A. IncobotulinumtoxinA Injection for Temporomandibular Joint Disorder. Annals Of Otology Rhinology & Laryngology 2017, 126: 328-333. PMID: 28290229, DOI: 10.1177/0003489417693013.Peer-Reviewed Original ResearchConceptsTemporomandibular disordersMuscles of masticationPain scoresTemporomandibular jointSaline injectionMuscle tenderness scoresPreinjection pain scoreAverage pain scorePain medication usageTemporomandibular joint disordersGroup one monthIncobotulinumtoxinA groupsIncobotulinumtoxinA injectionsPain medicationExact pathophysiologyPain scaleSignificant painMedication usageAssociated symptomsJoint disordersMasticatory musclesPainPatientsConventional treatmentMuscle disorders
2016
Gender differences in onabotulinum toxin A dosing for adductor spasmodic dysphonia
Lerner MZ, Lerner BA, Patel AA, Blitzer A. Gender differences in onabotulinum toxin A dosing for adductor spasmodic dysphonia. The Laryngoscope 2016, 127: 1131-1134. PMID: 27633917, DOI: 10.1002/lary.26265.Peer-Reviewed Original ResearchConceptsAdductor spasmodic dysphoniaSpasmodic dysphoniaOnabotulinum toxinChart reviewFemale groupOnabotulinum Toxin A InjectionsRetrospective chart reviewBotulinum toxin injectionSenior author's databaseAbductor spasmodic dysphoniaIndependent sample twoA injectionAverage followSymptom controlOromandibular dystoniaToxin injectionFemale patientsRetrospective reviewAlternate diagnosisBotulinum toxinAntibody formationFemale genderPossible inverse relationshipInclusion criteriaThyroarytenoid muscle
2014
Intravenous mesenchymal stem cell therapy after recurrent laryngeal nerve injury: A preliminary study
Lerner MZ, Matsushita T, Lankford KL, Radtke C, Kocsis JD, Young NO. Intravenous mesenchymal stem cell therapy after recurrent laryngeal nerve injury: A preliminary study. The Laryngoscope 2014, 124: 2555-2560. PMID: 25043703, DOI: 10.1002/lary.24798.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBiopsy, NeedleDisease Models, AnimalImmunohistochemistryInfusions, IntravenousLaryngoscopyMesenchymal Stem CellsMicroscopy, ConfocalNerve CrushNerve RegenerationPilot ProjectsRandom AllocationRatsRats, Sprague-DawleyRecurrent Laryngeal NerveRecurrent Laryngeal Nerve InjuriesStem Cell TransplantationTreatment OutcomeVocal Cord ParalysisConceptsRecurrent laryngeal nerve injuryLaryngeal nerve injuryFunctional recoveryMesenchymal stem cellsWeeks postinjuryCrush injuryNerve injuryIntravenous administrationMesenchymal stem cell therapyComplete nerve transectionFellowship-trained laryngologistsFunctional recovery scoresGreater functional recoveryVocal fold mobilityVocal fold immobilitySpinal cord injuryStatistical significanceSprague-Dawley ratsPotential beneficial effectsStem cell therapyLeft RLNNerve transectionCord injuryIntravenous infusionNeurotrophic factor