2021
DNA glycosylase deficiency leads to decreased severity of lupus in the Polb-Y265C mouse model
Paluri SL, Burak M, Senejani AG, Levinson M, Rahim T, Clairmont K, Kashgarian M, Alvarado-Cruz I, Meas R, Cardó-Vila M, Zeiss C, Maher S, Bothwell ALM, Coskun E, Kant M, Jaruga P, Dizdaroglu M, Lloyd R, Sweasy JB. DNA glycosylase deficiency leads to decreased severity of lupus in the Polb-Y265C mouse model. DNA Repair 2021, 105: 103152. PMID: 34186496, PMCID: PMC8635285, DOI: 10.1016/j.dnarep.2021.103152.Peer-Reviewed Original Research
1994
Activation of heat-shock transcription factor by graded reductions in renal ATP, in vivo, in the rat.
Van Why S, Mann A, Thulin G, Zhu X, Kashgarian M, Siegel N. Activation of heat-shock transcription factor by graded reductions in renal ATP, in vivo, in the rat. Journal Of Clinical Investigation 1994, 94: 1518-1523. PMID: 7929828, PMCID: PMC295298, DOI: 10.1172/jci117492.Peer-Reviewed Original ResearchConceptsRenal cortexHsp-70 mRNA inductionCortical ATP levelsRenal ischemia resultsPartial aortic occlusionActivation of HSFATP levelsCellular ATPHSF activationHSP-70 mRNAReduction of ATPAortic occlusionPreocclusion levelsProfound fallTotal occlusionIschemia resultsPreocclusion valuesHeat shock transcription factorLow-level expressionMetabolic consequencesVivo 31P NMR spectroscopyControl valuesHSP-70Vigorous responseRenal ATPImmature Renal Tubules Are Resistant to Prolonged Anoxia
Gaudio K, Thulin G, Ardito T, Kashgarian M, Siegel N. Immature Renal Tubules Are Resistant to Prolonged Anoxia. Pediatric Research 1994, 35: 152-156. PMID: 8165048, DOI: 10.1203/00006450-199402000-00005.Peer-Reviewed Original Research
1976
Lupus nephritis: natural history and therapy.
Hecht B, Siegel N, Kashgarian M, Hayslett J. Lupus nephritis: natural history and therapy. Perspectives In Nephrology And Hypertension 1976, 3: 21-41. PMID: 175347.Peer-Reviewed Original Research