2024
Safety Profile Comparison of 2 Smooth Tissue Expander Types
Almeida M, Alper D, Williams M, Shah R, Ihnat J, Hu K, Parikh N, Alperovich M. Safety Profile Comparison of 2 Smooth Tissue Expander Types. Annals Of Plastic Surgery 2024, 93: 178-182. PMID: 38980932, DOI: 10.1097/sap.0000000000004019.Peer-Reviewed Original ResearchConceptsBody mass indexComplication rateDrain durationMass indexAcellular dermal matrix useRetrospective review of patientsReview of patientsHigher body mass indexSmooth tissue expandersPain scoresChemotherapy exposureRetrospective reviewCapsular contractureSmooth implantsSafety profileWound breakdownFilling volumePatient comorbiditiesPerioperative informationCancer characteristicsMultivariate analysisComplicationsTissue expanderRadiation exposureMatrix use
2023
Breast implant capsule-associated squamous cell carcinoma: A systematic review and individual patient data meta-analysis
Yeow M, Ching A, Guillon C, Alperovich M. Breast implant capsule-associated squamous cell carcinoma: A systematic review and individual patient data meta-analysis. Journal Of Plastic Reconstructive & Aesthetic Surgery 2023, 86: 24-32. PMID: 37666057, DOI: 10.1016/j.bjps.2023.08.002.Peer-Reviewed Original ResearchConceptsIndividual patient dataSCC diagnosisPatient dataSystematic reviewJoanna Briggs Institute critical appraisal toolsDisease-free survivalMajority of patientsSquamous cell carcinomaRisk of biasRisk of malignancyCritical appraisal toolExtracapsular spreadMean followOverall survivalMedian ageMedian timeCell carcinomaBreast implantationImplant removalPatientsBreast augmentationUS FoodDrug AdministrationBreast implantsAppraisal tool
2020
Surgical Outcomes of Mastectomy with Immediate Autologous Reconstruction Followed by Radiation
Heller DR, Zhuo H, Zhang Y, Parikh N, Fusi S, Alperovich M, Lannin DR, Higgins SA, Avraham T, Killelea BK. Surgical Outcomes of Mastectomy with Immediate Autologous Reconstruction Followed by Radiation. Annals Of Surgical Oncology 2020, 28: 2169-2179. PMID: 32974699, DOI: 10.1245/s10434-020-09122-0.Peer-Reviewed Original ResearchConceptsPostmastectomy radiation therapyLarge institutional cohortProbability of complicationsImmediate autologous reconstructionAutologous reconstructionMultivariable analysisInstitutional cohortFlap outcomesRadiation-related complicationsRisk of complicationsChest wall asymmetryMethodsMedical recordsNodal radiationMedian followNeoadjuvant chemotherapyPrimary endpointResultsOne hundredSurgical outcomesFat necrosisFlap complicationsImmediate reconstructionReoperationRadiation therapyComplicationsFat graftingNeurologic Characterization of Craniosynostosis: Can Direct Brain Recordings Predict Language Development?
Wu R, Nie J, Abraham P, Halligan T, Gabrick K, Peck CJ, Sawh-Martinez R, Steinbacher DM, Alperovich M, McPartland J, Persing JA. Neurologic Characterization of Craniosynostosis: Can Direct Brain Recordings Predict Language Development? Journal Of Craniofacial Surgery 2020, 32: 78-82. PMID: 32941205, DOI: 10.1097/scs.0000000000007004.Peer-Reviewed Original ResearchConceptsNeural responsesLanguage deficitsLanguage developmentERP assessmentMetopic patientsMismatch negativity waveLarger negative amplitudesLong-term cognitionLanguage achievementCognitive outcomesMMNBrain recordingsInfant developmentBayley ScalesNegative amplitudeBSID scoresEEG testingBSIDDeficitsElectroencephalogramNeurocognitionCognitionSpeechStimuliYears of ageRisk of peri-operative complications in children receiving preoperative steroids
Mets EJ, Chouairi F, Mirza H, Allam O, Park KE, Junn A, Alperovich M. Risk of peri-operative complications in children receiving preoperative steroids. Pediatric Surgery International 2020, 36: 1345-1352. PMID: 32918623, DOI: 10.1007/s00383-020-04742-9.Peer-Reviewed Original ResearchConceptsAdverse eventsPediatric patientsSteroid usePreoperative steroidsNational Surgical Quality Improvement Project Pediatric databaseThirty-day adverse eventsPropensity scorePostoperative adverse eventsPeri-operative complicationsPediatric surgery patientsSimilar larger studiesMore comorbiditiesPerioperative impactHospital stayPerioperative complicationsAdult patientsPatient demographicsSteroid treatmentSurgery patientsSurgical variablesWound dehiscenceSurgical outcomesPediatric databasePatientsLarger studyWorse overall health status negatively impacts satisfaction with breast reconstruction
Mehta SK, Olawoyin O, Chouairi F, Duy PQ, Mets EJ, Gabrick KS, Le NK, Avraham T, Alperovich M. Worse overall health status negatively impacts satisfaction with breast reconstruction. Journal Of Plastic Reconstructive & Aesthetic Surgery 2020, 73: 2056-2062. PMID: 32972879, DOI: 10.1016/j.bjps.2020.08.093.Peer-Reviewed Original ResearchConceptsBREAST-Q scoresPatient-reported outcomesOverall health statusBreast reconstructionOverall healthASA classificationHealth statusGeneral linear modelAnesthesiologists physical status classificationYale-New Haven HospitalWorse overall health statusBREAST-Q outcomesHealth-related qualityPhysical status classificationNew Haven HospitalEffect of ASAASA 1Independent predictorsPatient factorsPostoperative satisfactionBreast surgeryPatient satisfactionASA 2PatientsRelevant covariatesSpring-Assisted Strip Craniectomy Versus Cranial Vault Remodeling: Long-Term Psychological, Behavioral, and Executive Function Outcomes.
Chandler L, Allam O, Park KE, Smetona J, Gabrick KS, Wu RT, Morgan C, Park SE, Chapman LA, Couture DE, David LR, Runyan CM, Persing JA, Alperovich M. Spring-Assisted Strip Craniectomy Versus Cranial Vault Remodeling: Long-Term Psychological, Behavioral, and Executive Function Outcomes. Journal Of Craniofacial Surgery 2020, 31: 2101-2105. PMID: 32890160, DOI: 10.1097/scs.0000000000006806.Peer-Reviewed Original ResearchConceptsExecutive function outcomesExecutive functioning skillsBehavior Rating InventoryBehavior Assessment SystemSocial withdrawal symptomsExecutive functionRating InventoryBASC-2Term PsychologicalNon-syndromic sagittal synostosisCohen's dSecond editionSAS groupChildrenFunction outcomesWithdrawal symptomsPsychologicalAssessment systemBehavioralSkillsParentsCaregiversInventoryExecutivesWhat Is the Difference in Cranial Base Morphology in Isolated and Syndromic Bicoronal Synostosis?
Lu X, Forte AJ, Wilson AT, Park KE, Allam O, Mozaffari MA, Alperovich M, Steinbacher DM, Alonso N, Persing JA. What Is the Difference in Cranial Base Morphology in Isolated and Syndromic Bicoronal Synostosis? Plastic & Reconstructive Surgery 2020, 146: 599-610. PMID: 32842109, DOI: 10.1097/prs.0000000000007068.Peer-Reviewed Original ResearchComparison of Neurocognitive Outcomes in Postoperative Adolescents with Unilateral Coronal Synostosis.
Wu RT, Gabrick KS, Singh A, Landi N, Taylor JA, Bartlett SP, Persing JA, Alperovich M. Comparison of Neurocognitive Outcomes in Postoperative Adolescents with Unilateral Coronal Synostosis. Plastic & Reconstructive Surgery 2020, 146: 614-619. PMID: 32842112, DOI: 10.1097/prs.0000000000007067.Peer-Reviewed Original ResearchConceptsPerformance intelligence quotientVisual-motor integrationVerbal intelligence quotientIntelligence quotientMean full-scale intelligence quotientMotor integrationLeft-sided patientsRight-side patientsNonsyndromic craniosynostosisLong-term functionLarge population studiesCranial vaultHigh motor coordinationMotor achievementsUnilateral coronal synostosisFull-scale intelligence quotientIndependent predictorsFemale patientsStudy cohortNeurodevelopmental assessmentAverage intelligence quotient scoresMean ageControl subjectsNeurocognitive outcomesIntelligence quotient scoresManagement of recurrent bilateral multifocal pseudoangiomatous stromal hyperplasia (PASH)
Xu X, Persing SM, Allam O, Park KE, Mozaffari MA, Lannin DR, Bossuyt V, Alperovich M. Management of recurrent bilateral multifocal pseudoangiomatous stromal hyperplasia (PASH). The Breast Journal 2020, 26: 1814-1817. PMID: 32562297, DOI: 10.1111/tbj.13950.Peer-Reviewed Original ResearchConceptsPseudoangiomatous stromal hyperplasiaStromal hyperplasiaBilateral mastectomyReduction mammoplastyTwo-stage implant-based breast reconstructionImplant-based breast reconstructionExcellent aesthetic outcomesPain reliefBreast enlargementStandard treatmentBreast reconstructionFocal excisionReconstructive surgeryRare caseConservative optionsAesthetic outcomeHyperplastic conditionsMastectomyHyperplasiaMammoplastyMacromastiaPatientsSurgeryExcisionBreastPatients with psychiatric illness report worse patient‐reported outcomes and receive lower rates of autologous breast reconstruction
Mehta SK, Sheth AH, Olawoyin O, Chouairi F, Gabrick KS, Allam O, Park KE, Avraham T, Alperovich M. Patients with psychiatric illness report worse patient‐reported outcomes and receive lower rates of autologous breast reconstruction. The Breast Journal 2020, 26: 1931-1936. PMID: 32529691, DOI: 10.1111/tbj.13936.Peer-Reviewed Original ResearchConceptsPatient-reported outcomesPsychiatric diagnosisBreast reconstructionBinary logistic regressionAutologous reconstructionReconstructive modalityWorse patient-reported outcomesLogistic regressionBREAST-Q surveysBREAST-Q scoresAutologous breast reconstructionGeneral linear modelQuality of lifeModalities of reconstructionChi-squared testPsychiatric wellASA classificationIndependent predictorsTertiary hospitalInsurance statusImplant reconstructionRisk populationsPatientsDiagnosisModule scoresRadiographic Predictors of FACE-Q Outcomes Following Non-Operative Orbital Floor Fracture Management.
Gabrick K, Smetona J, Iyengar R, Dinis J, Chouiari F, Peck CJ, Persing J, Alperovich M. Radiographic Predictors of FACE-Q Outcomes Following Non-Operative Orbital Floor Fracture Management. Journal Of Craniofacial Surgery 2020, 31: e388-e391. PMID: 32176015, DOI: 10.1097/scs.0000000000006356.Peer-Reviewed Original ResearchConceptsOrbital floor fracture managementOrbital floor fracturesPercent of patientsNon-operative managementPsychosocial distressFloor fracturesRadiographic findingsFracture managementMaxillary sinusYale-New Haven HospitalRight-sided fracturesAppearance-related psychosocial distressInferior rectus muscleLong-term outcomesPatient-reported questionnaireRectus muscle belliesMultiple surgical subspecialtiesNew Haven HospitalMean fracture areaBony injuriesInferior rectusOperative indicationsClinical findingsCommon injuriesMean durationMicrosurgery in the sickle cell trait population: is it actually safe?
Abraham PF, Allam O, Park KE, Alperovich M. Microsurgery in the sickle cell trait population: is it actually safe? BMJ Case Reports 2020, 13: e234924. PMID: 32381529, PMCID: PMC7222880, DOI: 10.1136/bcr-2020-234924.Peer-Reviewed Original ResearchConceptsSickle cell traitCell traitSickle cell disease patientsSickle cell trait patientsPoor vascular flowPostoperative day 2Indocyanine green angiographySickle cell diseaseMicrovascular free flapsSickle cell disease populationVenous congestionDisease patientsGreen angiographyVenous anastomosisCell diseaseMicrovascular compromiseDisease populationFree flapPatent anastomosisDay 2Flap transferVascular flowArterial Doppler signalsPatientsOperating roomCranial Fossa Development in Differing Subtypes of Crouzon Syndrome.
Lu X, Forte AJ, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Cranial Fossa Development in Differing Subtypes of Crouzon Syndrome. Journal Of Craniofacial Surgery 2020, 31: 673-677. PMID: 32049910, DOI: 10.1097/scs.0000000000006181.Peer-Reviewed Original ResearchImpact of socioeconomic status on psychological functioning in survivorship following breast cancer and reconstruction
Le NK, Gabrick KS, Chouairi F, Mets EJ, Avraham T, Alperovich M. Impact of socioeconomic status on psychological functioning in survivorship following breast cancer and reconstruction. The Breast Journal 2020, 26: 1695-1701. PMID: 32337778, DOI: 10.1111/tbj.13849.Peer-Reviewed Original ResearchConceptsPatients' socioeconomic statusQuality of lifeBreast reconstructionBreast cancerSocioeconomic statusCancer treatmentPatient-reported outcome measuresSingle academic centerInitial cancer treatmentBreast cancer treatmentPopulation health risk factorsHealth risk factorsLow socioeconomic statusHigher socioeconomic statusStudy time periodBaseline comorbiditiesCancer stageRisk factorsOutcome measuresAnalysis of covariancePatient experienceAcademic centersPatientsSignificant positive correlationSatisfaction domainsSMAD6 Genotype Predicts Neurodevelopment in Nonsyndromic Craniosynostosis.
Wu RT, Timberlake AT, Abraham PF, Gabrick KS, Lu X, Peck CJ, Sawh-Martinez RF, Steinbacher DM, Alperovich MA, Persing JA. SMAD6 Genotype Predicts Neurodevelopment in Nonsyndromic Craniosynostosis. Plastic & Reconstructive Surgery 2020, 145: 117e-125e. PMID: 31592950, DOI: 10.1097/prs.0000000000006319.Peer-Reviewed Original ResearchMeSH KeywordsCase-Control StudiesChildChild BehaviorChild DevelopmentChild, PreschoolCraniosynostosesCraniotomyDevelopmental DisabilitiesDouble-Blind MethodFemaleFollow-Up StudiesHumansInfantIntelligence TestsLoss of Function MutationMalePlastic Surgery ProceduresProspective StudiesSkullSmad6 ProteinTreatment OutcomeImpact of Insurance Payer on Type of Breast Reconstruction Performed.
Chouairi F, Mets EJ, Gabrick KS, Dinis J, Avraham T, Alperovich M. Impact of Insurance Payer on Type of Breast Reconstruction Performed. Plastic & Reconstructive Surgery 2020, 145: 1e-8e. PMID: 31881596, DOI: 10.1097/prs.0000000000006315.Peer-Reviewed Original ResearchConceptsBreast reconstructionBreast reconstruction modalityAcademic medical centerOdds ratioMedical CenterMuscle-sparing transverse rectus abdominis myocutaneous flapPerforator flapTissue expander/implant breast reconstructionExpander/implant breast reconstructionMicrovascular autologous breast reconstructionTransverse rectus abdominis myocutaneous flapPerforator flap breast reconstructionIncome quartileCLINICAL QUESTION/LEVELReconstruction modalitiesSame academic medical centerRectus abdominis myocutaneous flapAutologous breast reconstructionFlap breast reconstructionImplant breast reconstructionHighest income quartileLowest income quartileInsurance typeMicrovascular reconstructionChi-square analysis
2019
Breast reconstruction patterns and outcomes in academic and community practices within a single institution
Gabrick K, Alperovich M, Chouari F, Mets EJ, Reinhart M, Dinis J, Avraham T. Breast reconstruction patterns and outcomes in academic and community practices within a single institution. The Breast Journal 2019, 26: 924-930. PMID: 31788914, DOI: 10.1111/tbj.13693.Peer-Reviewed Original ResearchConceptsYale-New Haven HospitalBreast reconstructionMore patientsSingle institutionPlastic surgeonsCommercial insuranceHigh rateRetrospective chart reviewPrevalence of diabetesSimilar complication ratesNipple-sparing mastectomyHigher infection rateAP cohortChart reviewComplication rateCP cohortPostoperative outcomesPreoperative historySurgery ratesPsychiatric comorbidityInsurance statusAutologous reconstructionPractice patternsMedicaid patientsGreater prevalenceCranial Fossa Volume in Differing Subtypes of Apert Syndrome.
Lu X, Forte AJ, Wilson A, Alperovich M, Steinbacher DM, Alonso N, Persing JA. Cranial Fossa Volume in Differing Subtypes of Apert Syndrome. Journal Of Craniofacial Surgery 2019, 30: 2345-2349. PMID: 31609946, DOI: 10.1097/scs.0000000000005785.Peer-Reviewed Original ResearchSecondary Cleft Rhinoplasty in 1720 Patients: Are National Practices Consistent With Guidelines?
Chouairi F, Torabi SJ, Gabrick KS, Persing JA, Alperovich M. Secondary Cleft Rhinoplasty in 1720 Patients: Are National Practices Consistent With Guidelines? The Cleft Palate-Craniofacial Journal 2019, 57: 438-443. PMID: 31594399, DOI: 10.1177/1055665619879830.Peer-Reviewed Original ResearchConceptsSecondary cleft rhinoplastyCleft rhinoplastyMean ageAdjunct procedureNational Surgical Quality Improvement Program Pediatric databaseSecondary cleft lip rhinoplastyTympanostomy tube placementCleft lip rhinoplastySeptal componentFisher's exact testCleft lip revisionCommon adjunct procedureImmature patientsPatient ageBilateral patientsFemale patientsTube placementRib graftingChi-square analysisInclusion criteriaSurgical proceduresLip revisionMAIN OUTCOMEPatientsAuricular graft