2020
Classification of Subtypes of Crouzon Syndrome Based on the Type of Vault Suture Synostosis.
Lu X, Sawh-Martinez R, Forte AJ, Wu R, Cabrejo R, Wilson A, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Classification of Subtypes of Crouzon Syndrome Based on the Type of Vault Suture Synostosis. Journal Of Craniofacial Surgery 2020, 31: 678-684. PMID: 32068731, DOI: 10.1097/scs.0000000000006173.Peer-Reviewed Original ResearchConceptsClass IIICrouzon syndromeClass IClass IISuture involvementSuture synostosisSimilar craniofacial characteristicsComputed tomography scanClassification of subtypesSurgical interventionMorphology of patientsAnatomic deformityTomography scanSurgical techniqueCT scanDifferent subtypesSagittal synostosisSyndromeClass IVPremature closureCraniofacial characteristicsSevere craniofacial malformationsCranial base lengthSynostosisDifferent pathologiesRacial disparity of Crouzon syndrome in maxilla and mandible
Lu X, Forte AJ, Fan F, Zhang Z, Teng L, Yang B, Alperovich M, Steinbacher DM, Alonso N, Persing JA. Racial disparity of Crouzon syndrome in maxilla and mandible. International Journal Of Oral And Maxillofacial Surgery 2020, 49: 1566-1575. PMID: 32362538, DOI: 10.1016/j.ijom.2020.04.005.Peer-Reviewed Original ResearchConceptsAsian patientsCaucasian patientsCrouzon syndrome patientsCrouzon syndromeSyndrome patientsRacial disparitiesAnteroposterior maxillary lengthMidface profileTomography scanPatientsMandibular volumeCaucasian controlsCraniosynostosis patientsMaxillary positioningMaxillary lengthSyndromeVolume deficiencyANB angleAsian controlsMandibular lengthBackward displacementMaterialise softwareMaxillaSame extentMaxilla length
2019
What Is the Skull Structure Influence of Squamosal Suture Synostosis in Nonsyndromic and Syndromic Crouzon Craniosynostosis?
Lu X, Chen G, Forte AJ, Cabrejo R, Singh A, Kyle G, Steinbacher DM, Alperovich M, Alonso N, Persing JA. What Is the Skull Structure Influence of Squamosal Suture Synostosis in Nonsyndromic and Syndromic Crouzon Craniosynostosis? Journal Of Craniofacial Surgery 2019, 30: 1671-1675. PMID: 30950948, DOI: 10.1097/scs.0000000000005396.Peer-Reviewed Original ResearchConceptsMiddle cranial fossaAnterior cranial fossaCranial fossaPosterior cranial fossaSquamosal synostosisFossa volumeCrouzon syndromeSquamosal suture synostosisComputed tomography scanCranial volumeNonsyndromic craniosynostosis patientsVolume reductionSevere volume reductionTomography scanNormal controlsMorphologic effectsCraniosynostosis patientsFossaPremature closureSyndromic conditionsSuture synostosisSyndromic synostosisFrankfort horizontal planeSynostosisThree-dimensional cephalometryEnlarged anterior cranial fossa and restricted posterior cranial fossa, the disproportionate growth of basicranium in Crouzon syndrome
Lu X, Forte AJ, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Enlarged anterior cranial fossa and restricted posterior cranial fossa, the disproportionate growth of basicranium in Crouzon syndrome. Journal Of Cranio-Maxillofacial Surgery 2019, 47: 1426-1435. PMID: 31331854, DOI: 10.1016/j.jcms.2019.06.003.Peer-Reviewed Original ResearchConceptsPosterior cranial fossa volumePosterior cranial fossaCranial fossaFossa volumeCrouzon syndrome patientsCrouzon syndromeSyndrome patientsCT scanSegmental anteriorSurgical treatment planPreoperative CT scanAnterior cranial fossaMonths of ageMiddle cranial fossaPosterior cranial expansionNormal intracranial volumeIntracranial volume measurementsTreatment planIntracranial volumePatientsFossaSyndromeCranial expansionCranial volumeAnteriorAnalysis of Airway and Midface in Crouzon Syndromes
Forte AJ, Lu X, Hashim PW, Steinbacher DM, Alperovich M, Persing JA, Alonso N. Analysis of Airway and Midface in Crouzon Syndromes. Annals Of Plastic Surgery 2019, Publish Ahead of Print: &na;. PMID: 30633021, DOI: 10.1097/sap.0000000000001740.Peer-Reviewed Original ResearchConceptsPharyngeal airway volumeComputed tomography scanAirway volumeControl subjectsTomography scanCrouzon syndromeAge-matched control subjectsAnalysis of airwaysSevere respiratory impairmentNasal airway volumePosterior pharyngeal wallEarly mixed dentitionCrouzon groupSurgical interventionRespiratory impairmentUpper airwaySoft tissue measurementsPharyngeal wallPosterior tongueMixed dentitionAirwayPatientsSyndromeVolumetric assessmentT-testAssociation of Regional Cranial Base Deformity and Ultimate Structure in Crouzon Syndrome.
Lu X, Jorge Forte A, Sawh-Martinez R, Wu R, Cabrejo R, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Association of Regional Cranial Base Deformity and Ultimate Structure in Crouzon Syndrome. Plastic & Reconstructive Surgery 2019, 143: 1233e-1243e. PMID: 31136487, DOI: 10.1097/prs.0000000000005643.Peer-Reviewed Original Research
2018
Orbit, zygoma, and maxilla growth patterns in Crouzon syndrome
Lu X, Forte AJ, Sawh-Martinez R, Wu R, Cabrejo R, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Orbit, zygoma, and maxilla growth patterns in Crouzon syndrome. International Journal Of Oral And Maxillofacial Surgery 2018, 48: 309-321. PMID: 30389113, DOI: 10.1016/j.ijom.2018.10.013.Peer-Reviewed Original ResearchConceptsCrouzon syndromeCT scanAnteroposterior lengthWidth of maxillaPreoperative CT scanMonths-2 yearsMonths of agePrincipal deformityControl subjectsGlobe projectionAge subgroupsMaxillary wideningSecondary deformitiesOrbital wallAnterior protrusionSyndromeFacial malformationsMonthsDeformityAnteroposterior positionZygomatic regionCranial baseZygomaMalformationsMaterialise softwareFacial Malformation in Crouzon’s Syndrome Is Consistent with Cranial Base Development in Time and Space
Lu X, Forte AJ, Sawh-Martinez R, Madari S, Wu R, Cabrejo R, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Facial Malformation in Crouzon’s Syndrome Is Consistent with Cranial Base Development in Time and Space. Plastic & Reconstructive Surgery Global Open 2018, 6: e1963. PMID: 30534503, PMCID: PMC6250456, DOI: 10.1097/gox.0000000000001963.Peer-Reviewed Original ResearchCranial base deformitySyndrome patientsCrouzon syndromeFrankfort horizontal planeSurgical decision makingAnterior cranial fossaCranial baseMonths of ageCranial base developmentEvident morphologic changesCrouzon syndrome patientsAnterior cranial baseSella-nasion planeTomography scanCranial fossaCrouzon patientsSyndromeMorphologic changesPatientsMandibular planeFacial malformationsPosterior cranial baseDeformityMaxillary planeSella-Nasion