1993
Benzodiazepines in Congestive Heart Failure: Effects of Temazepam on Arousability and Cheyne-Stokes Respiration
Biberdorf D, Steens R, Millar T, Kryger M. Benzodiazepines in Congestive Heart Failure: Effects of Temazepam on Arousability and Cheyne-Stokes Respiration. Sleep 1993, 16: 529-538. PMID: 8235237, DOI: 10.1093/sleep/16.6.529.Peer-Reviewed Original ResearchConceptsCheyne-Stokes respirationCongestive heart failureTotal sleep timePercentage of TSTApnea/hypopnea indexOxygen saturationTotal wake timeEffects of temazepamHeart failureSleep architectureDouble-blind crossover trialSevere congestive heart failureOvernight oxygen saturationStage 1 sleepHours of sleepSleep stage proportionsCHF patientsHypopnea indexMale patientsDaytime somnolenceCrossover trialSignificant changesFrequent arousalsDaytime alertnessSleep time
1991
Effect of Theophylline on Lung Function Tests, Sleep Quality, and Nighttime SaO2 in Children with Cystic Fibrosis
Avital A, Sanchez I, Holbrow J, Kryger M, Chernick V. Effect of Theophylline on Lung Function Tests, Sleep Quality, and Nighttime SaO2 in Children with Cystic Fibrosis. American Journal Of Respiratory And Critical Care Medicine 1991, 144: 1245-1249. PMID: 1741534, DOI: 10.1164/ajrccm/144.6.1245.Peer-Reviewed Original ResearchConceptsEffect of theophyllineCystic fibrosisMicrograms/Heart rateGroup 2Better baseline lung functionT blood levelsBaseline lung functionIncidence of apneaLung function testsSerum T levelsLower heart rateTotal wake timePulmonary functionLung functionSerum levelsFunction testsMean SaO2Blood levelsSleep qualitySleep efficiencyGroup 1Sleep laboratoryT levelsWake timeSubjective Versus Objective Evaluation of Hypnotic Efficacy: Experience with Zolpidem
Kryger M, Steljes D, Pouliot Z, Neufeld H, Odynski T. Subjective Versus Objective Evaluation of Hypnotic Efficacy: Experience with Zolpidem. Sleep 1991, 14: 399-407. PMID: 1759092, DOI: 10.1093/sleep/14.5.399.Peer-Reviewed Original ResearchConceptsTotal sleep timeSleep latencyNumber of awakeningsSleep timePSG findingsPersistent sleepHypnotic efficacySleep qualityPatients' subjective evaluationSubjective sleep qualityDecreased sleep latencyQuality of sleepShortened sleep latencyTotal wake timeObjective measuresPolysomnographic findingsSleepy patientsChronic insomniaWeeks' useIndividual patientsSleep efficiencySubjective reductionSubjective increaseObjective efficacyPatients