2022
PAP Therapy for Sleep Breathing Disorders: Good Policies and Practices
Ali M, Kryger M. PAP Therapy for Sleep Breathing Disorders: Good Policies and Practices. 2022, 95-100. DOI: 10.1007/978-3-030-93146-9_8.ChaptersSleep-disordered breathingPAP adherencePAP therapyPositive airway pressure therapyExtensive patient educationAirway pressure therapySevere sleep apneaSleep breathing disordersTreatment of choiceLong-term usePAP initiationPAP usagePAP useSleep apneaBreathing disordersPressure therapySymptomatic burdenPAP complianceAdequate adherencePatient educationOptimal managementPoor maskPatientsTherapySocioeconomic status
2018
Treating Sleep-Related Breathing Disorders
Won C, Mohsenin V, Kryger M. Treating Sleep-Related Breathing Disorders. 2018, 105-123. DOI: 10.1007/978-1-4939-8607-1_9.Peer-Reviewed Original ResearchPositive airway pressure therapySignificant symptomatic benefitAirway pressure therapySleep-disordered breathingMental health outcomesNeuropsychomotor functionsPAP therapyMainstay treatmentSymptomatic benefitPAP adherenceBreathing disordersPressure therapySide effectsHealth outcomesPatientsTherapyEffective alternativeAdherenceRobust evidenceTolerabilityBreathingSleep
2016
Positive Airway Pressure Therapy for Obstructive Sleep Apnea
Weiss P, Kryger M. Positive Airway Pressure Therapy for Obstructive Sleep Apnea. Otolaryngologic Clinics Of North America 2016, 49: 1331-1341. PMID: 27720457, DOI: 10.1016/j.otc.2016.07.004.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsPositive airway pressureObstructive sleep apneaAirway pressureSleep apneaMild obstructive sleep apneaPositive airway pressure therapyContinuous positive airway pressureSevere obstructive sleep apneaObstructive sleep apnea syndromeSleep-related breathing disordersConcomitant cardiovascular disordersAirway pressure therapyFirst-line therapySleep apnea syndromeAdaptive support ventilationEvaluation of adherenceEffectiveness of treatmentApnea syndromeSupport ventilationBreathing disordersPressure therapyCardiovascular disordersApneaTherapyPressure support
2015
Clinical consequences and economic costs of untreated obstructive sleep apnea syndrome
Knauert M, Naik S, Gillespie MB, Kryger M. Clinical consequences and economic costs of untreated obstructive sleep apnea syndrome. World Journal Of Otorhinolaryngology - Head And Neck Surgery 2015, 1: 17-27. PMID: 29204536, PMCID: PMC5698527, DOI: 10.1016/j.wjorl.2015.08.001.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsObstructive sleep apnea syndromeSleep apnea syndromeUntreated obstructive sleep apnea syndromeApnea syndromeEffective therapyPoor patient acceptanceStart date restrictionLack of diagnosisSignificant economic burdenEnglish-language studiesExcessive daytimeSleep apneaPatient acceptanceCardiovascular diseaseClinical consequencesDate restrictionsEconomic burdenMetabolic diseasesPubMed databaseAbnormal physiologySyndromeTherapyLack of accessDiseaseTreatment
2014
Evaluation of a new pediatric positive airway pressure mask.
Kushida CA, Halbower AC, Kryger MH, Pelayo R, Assalone V, Cardell CY, Huston S, Willes L, Wimms AJ, Mendoza J. Evaluation of a new pediatric positive airway pressure mask. Journal Of Clinical Sleep Medicine 2014, 10: 979-84. PMID: 25142768, PMCID: PMC4153116, DOI: 10.5664/jcsm.4030.Peer-Reviewed Original ResearchConceptsContinuous positive airway pressurePAP therapyPositive airway pressure maskPositive airway pressureParents/guardiansAirway pressureBaseline polysomnographyCPAP maskChildren's earsPressure maskPatientsAge groupsChildren's sleepUpper lipPolysomnographyChildrenTherapySleepEarYearsAHIClinicClinicians
2008
The Circuitous Route to Diagnosing Sleep Disorders in Women: Health Care Utilization and Benefits of Improved Awareness for Sleep Disorders
Banno K, Kryger M. The Circuitous Route to Diagnosing Sleep Disorders in Women: Health Care Utilization and Benefits of Improved Awareness for Sleep Disorders. Sleep Medicine Clinics 2008, 3: 133-140. DOI: 10.1016/j.jsmc.2007.10.004.Peer-Reviewed Original ResearchHealth care utilizationSleep disordersCare utilizationPrimary sleep disordersUntreated sleep disordersHealth care systemClinical presentationEarly diagnosisSleep problemsPsychiatric diseasesCare systemDisordersLack of awarenessWomenMental conditionMedical practitionersDiagnosisGender differencesTherapyDisease
1995
Medical treatment of sleep apnea
Wali S, Kryger M. Medical treatment of sleep apnea. Current Opinion In Pulmonary Medicine 1995, 1: 498-503. PMID: 9363089, DOI: 10.1097/00063198-199511000-00012.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsSleep apneaContinuous positive airway pressure therapyPositive airway pressure therapyContinuous positive airway pressureAirway pressure therapyPositive airway pressureObstructive sleep apneaCurrent treatment optionsTreatment of choiceAirway pressureNicotine treatmentPressure therapyTreatment optionsCommon disorderMedical treatmentDifficult patientsElectrical stimulationWeight lossDental appliancesApneaTherapyTreatmentUnwanted effectsTracheostomyPatients
1992
Polysomnography in Acutely III Intensive Care Unit Patients
Buckle P, Pouliot Z, Millar T, Kerr P, Kryger M. Polysomnography in Acutely III Intensive Care Unit Patients. CHEST Journal 1992, 102: 288-291. PMID: 1623769, DOI: 10.1378/chest.102.1.288.Peer-Reviewed Original ResearchConceptsCase reportDescriptive studyDouble-blind clinical trialIntensive care unit patientsStudy designCare unit patientsSeries of patientsCase report studySeries of casesUnit patientsCause of diseaseInvestigational protocolsClinical trialsClinical relevanceClinical researchReport studyChestGold standardPatientsReportPolysomnographyTherapyStudy
1988
Mortality and Apnea Index in Obstructive Sleep Apnea Experience in 385 Male Patients
He J, Kryger M, Zorick F, Conway W, Roth T. Mortality and Apnea Index in Obstructive Sleep Apnea Experience in 385 Male Patients. CHEST Journal 1988, 94: 9-14. PMID: 3289839, DOI: 10.1378/chest.94.1.9.Peer-Reviewed Original ResearchConceptsApnea indexObstructive sleep apneaNasal CPAPOSA patientsCumulative survivalObstructive sleep apnea experienceEight-year survivalMale OSAS patientsUntreated OSA patientsGreater mortalityYears of ageUPPP patientsLatter patientsMale patientsSleep apneaPatientsSurvival curvesMortalityTracheostomyCPAPSurvivalIndexApneaUPPPTherapy
1987
Trial of a Dopaminergic Antidepressant in Obstructive Sleep Apnea
George C, West P, Millar T, Kryger M. Trial of a Dopaminergic Antidepressant in Obstructive Sleep Apnea. Sleep 1987, 10: 180-183. PMID: 3589330, DOI: 10.1093/sleep/10.2.180.Peer-Reviewed Original ResearchConceptsObstructive sleep apneaAnticholinergic side effectsSleep apneaSide effectsImmune hemolytic anemiaCentral nervous system stimulant propertiesPharmacologic therapyUseful therapyEffective therapyUnacceptable incidenceDopaminergic antidepressantsHemolytic anemiaNomifensineRigorous scientific testingStimulant propertiesTherapyApneaAntidepressantsPatientsAnemiaDopaminergicIncidenceTrialsScientific testingProtriptyline
1985
Sleep and Respiration: A Postscript
Kryger M, White D, Zwillich C, Robinson R, Guilleminault C. Sleep and Respiration: A Postscript. Clinics In Chest Medicine 1985, 6: 713-718. PMID: 3853480, DOI: 10.1016/s0272-5231(21)00407-x.Chapters
1983
The role of protriptyline in obstructive sleep apnea.
Brownell L, Perez-Padilla R, West P, Kryger M. The role of protriptyline in obstructive sleep apnea. Bulletin Européen De Physiopathologie Respiratoire 1983, 19: 621-4. PMID: 6360257.Peer-Reviewed Original ResearchConceptsObstructive sleep apneaSleep apneaTreatment of mildLong-term treatmentTricyclic agentsObese patientsObstructive apneaClinical statusCrossover trialImproved oxygenationInvasive treatmentTerm treatmentPatientsApneaArousal frequencySomnolenceProtriptylineTreatmentTrialsOxygenationREMTherapyMildMonths
1980
The Effect of Low Flow Oxygen Therapy on the Chemical Control of Ventilation in Patients with Hypoxemic COPD1–3
Fleetham J, Bradley C, Kryger M, Anthonisen N. The Effect of Low Flow Oxygen Therapy on the Chemical Control of Ventilation in Patients with Hypoxemic COPD1–3. American Journal Of Respiratory And Critical Care Medicine 1980, 122: 833-40. PMID: 6779682, DOI: 10.1164/arrd.1980.122.6.833.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseHypoxemic chronic obstructive pulmonary diseaseOxygen therapyHypoxic responseLow-flow oxygen therapyCentral ventilatory driveFlow oxygen therapyNocturnal oxygen therapyObstructive pulmonary diseaseArterial O2 saturationNocturnal oxygenPulmonary diseaseSuch patientsVentilatory driveMinute ventilationInspiratory flowO2 saturationPatientsTherapyContinuous oxygenMonthsHypoxiaInitial responseHypoxemiaVentilation
1978
Treatment of Excessive Polycythemia of High Altitude with Respiratory Stimulant Drugs1–3
Kryger M, McCullough R, Collins D, Scoggin C, Weil J, Grover R. Treatment of Excessive Polycythemia of High Altitude with Respiratory Stimulant Drugs1–3. American Journal Of Respiratory And Critical Care Medicine 1978, 117: 455-64. PMID: 629480, DOI: 10.1164/arrd.1978.117.3.455.Peer-Reviewed Original ResearchConceptsMedroxyprogesterone acetateExcessive polycythemiaTidal volumeVentilatory responseArterial PCO2O2 saturationWeeks of therapyMonths of treatmentEffect of medroxyprogesteroneHypoxic ventilatory responseArterial O2 saturationNormal arterial PCO2Progestational agentsArterial PO2Normal lungStimulant effectsExcessive hypoxemiaPatientsMedroxyprogesteroneNormal valuesPolycythemiaDead spaceVentilationTherapyHematocrit