2020
The subcortical belly of sleep: New possibilities in neuromodulation of basal ganglia?
Hasegawa H, Selway R, Gnoni V, Beniczky S, Williams SCR, Kryger M, Ferini-Strambi L, Goadsby P, Leschziner GD, Ashkan K, Rosenzweig I. The subcortical belly of sleep: New possibilities in neuromodulation of basal ganglia? Sleep Medicine Reviews 2020, 52: 101317. PMID: 32446196, PMCID: PMC7679363, DOI: 10.1016/j.smrv.2020.101317.Peer-Reviewed Original ResearchConceptsBasal gangliaBasal ganglia disordersFunctional anatomyPhysiology of sleepSlow-wave sleepSleep-wake cycleOptogenetic mappingNeuromodulation strategiesSleep disordersREM sleepGangliaNeural plasticityNeural circuitsSleepFunctional imagingIntracranial recordingsHuman sleep disordersSleep mechanismsDisordersEmotional networkIntegral roleAnatomyBetter understandingNeuromodulation
2007
The visual scoring of sleep in adults.
Silber MH, Ancoli-Israel S, Bonnet MH, Chokroverty S, Grigg-Damberger MM, Hirshkowitz M, Kapen S, Keenan SA, Kryger MH, Penzel T, Pressman MR, Iber C. The visual scoring of sleep in adults. Journal Of Clinical Sleep Medicine 2007, 3: 121-31. PMID: 17557422, DOI: 10.5664/jcsm.26814.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2004
Sleep, health, and aging. Bridging the gap between science and clinical practice.
Kryger M, Monjan A, Bliwise D, Ancoli-Israel S. Sleep, health, and aging. Bridging the gap between science and clinical practice. Geriatrics 2004, 59: 24-6, 29-30. PMID: 14755865.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsExcessive daytime sleepinessPrevalence of insomniaProblems of sleepSlow-wave sleepQuality of lifeAdults age 65Age-related processesGeriatric populationDaytime sleepinessSleep disordersSleep efficiencyClinical practiceRestful sleepAge 65Depressed moodOlder populationSleepInsomniaLater lifeAdverse changesMemory problemsNight resultsComorbiditiesPopulationSleepiness
1999
Upper Airway Resistance Syndrome: Effect of Nasal Dilation, Sleep Stage, and Sleep Position
Bahammam A, Tate R, Manfreda J, Kryger M. Upper Airway Resistance Syndrome: Effect of Nasal Dilation, Sleep Stage, and Sleep Position. Sleep 1999, 22: 592-598. PMID: 10450594, DOI: 10.1093/sleep/22.5.592.Peer-Reviewed Original ResearchConceptsUpper airway resistance syndromeStage 1 sleepSleep positionNasal dilationDesaturation timeSleep architectureExternal nasal dilationArousal indexCardiorespiratory parametersSleep stagesNREM sleepNasal cross-sectional areaExternal nasal dilatorSlow-wave sleepObstructive sleepAirway collapsibilityConsecutive patientsNasal dilatorNasal obstructionResistance syndromeSupine positionIntrapharyngeal pressureIndirect markerWave sleepCrossover design
1996
L-DOPA/Carbidopa for Nocturnal Movement Disorders in Uremia
Walker S, Fine A, Kryger M. L-DOPA/Carbidopa for Nocturnal Movement Disorders in Uremia. Sleep 1996, 19: 214-218. PMID: 8723378, DOI: 10.1093/sleep/19.3.214.Peer-Reviewed Original ResearchConceptsL-dopa/carbidopaRestless legs syndromeSlow-wave sleepLeg movementsSleep timeTreatment of RLSMovement arousal indexNocturnal movement disordersSingle bedtime doseChronic hemodialysis patientsPeriodic limb movementsHours of sleepBedtime doseActive medicationHemodialysis patientsCrossover studyLegs syndromeUremic patientsArousal indexMovement disordersSleep disruptionFrequent dosingObjective improvementSleep disordersEffective treatment
1990
Sleep in Postpolio Syndrome
Steljes D, Kryger M, Kirk B, Millar T. Sleep in Postpolio Syndrome. CHEST Journal 1990, 98: 133-140. PMID: 2361379, DOI: 10.1378/chest.98.1.133.Peer-Reviewed Original ResearchConceptsNasal mask ventilationPost-polio patientsGroup 1 patientsNasal CPAPPoor sleep qualityMask ventilationMixed apneaSleep qualityHypoventilation syndromeRespiratory complaintsPercentage stage 1 sleepRapid eye movement (REM) sleepNasal mechanical ventilationNight-time polysomnographyPost-polio symptomsSignificant O2 desaturationGroup 2 patientsRespiratory muscle weaknessNumber of arousalsEye movement sleepImproved sleep qualityPost-polio syndromeStage 1 sleepTotal sleep timeSlow-wave sleep
1989
The effect of oxygen on respiration and sleep in patients with congestive heart failure.
Hanly P, Millar T, Steljes D, Baert R, Frais M, Kryger M. The effect of oxygen on respiration and sleep in patients with congestive heart failure. Annals Of Internal Medicine 1989, 111: 777-82. PMID: 2817624, DOI: 10.7326/0003-4819-111-10-777.Peer-Reviewed Original ResearchConceptsStable congestive heart failureCheyne-Stokes respirationCongestive heart failureHeart failureTotal sleep timeOxygen therapySleep timeStage 1 NREM sleepPlacebo-controlled crossover studyLow-flow oxygenNocturnal oxygen saturationNocturnal oxygen therapyOutpatient cardiology clinicApnea-hypopnea indexNumber of arousalsStage 1 sleepStage 2 sleepSlow-wave sleepHyperpneic phaseNocturnal hypoxemiaSleep hypoxemiaMale patientsNasal cannulaeCardiology clinicCrossover studyRespiration and Abnormal Sleep in Patients with Congestive Heart Failure
Hanly B, Millar T, Steljes D, Boert R, Frais M, Kryger M. Respiration and Abnormal Sleep in Patients with Congestive Heart Failure. CHEST Journal 1989, 96: 480-488. PMID: 2766808, DOI: 10.1378/chest.96.3.480.Peer-Reviewed Original ResearchConceptsCheyne-Stokes respirationCongestive heart failureStage 2 NREM sleepSlow-wave sleepSleep stage changesNREM sleepHyperpneic phaseHeart failureREM sleepAwake arterial oxygen saturationStable congestive heart failureSevere congestive heart failureStage 1Mean minimum SaO2Outcomes of patientsNumber of arousalsArterial oxygen saturationStage 1 sleepMinimum SaO2Severe hypoxemiaArterial oxygenationSignificant hypoxemiaClinical statusMean durationAbnormal sleepThe Effect of L-Tryptophan on Daytime Sleep Latency in Normals: Correlation with Blood Levels
George C, Millar T, Hanly P, Kryger M. The Effect of L-Tryptophan on Daytime Sleep Latency in Normals: Correlation with Blood Levels. Sleep 1989, 12: 345-353. PMID: 2669092, DOI: 10.1093/sleep/12.4.345.Peer-Reviewed Original ResearchConceptsSleep latencyBlood levelsRandom double-blind fashionRapid eye movement (REM) sleepDaytime sleep latencyL-tryptophan's effectsDouble-blind fashionEye movement sleepL-tryptophanSlow-wave sleepL-tryptophan levelsObjective sleepiness measuresKynurenic acidMovement sleepHealthy volunteersWave sleepDrug conditionsSeparate daysSleepSleepiness measuresPlaceboSignificant correlationEssential amino acidsDoseUrine