2024
Impact of the COVID-19 pandemic on participants in pragmatic clinical trials for chronic pain: implications for trial outcomes and beyond
Sellinger J, Gilstad-Hayden K, Lazar C, Seal K, Purcell N, Burgess D, Martino S, Heapy A, Higgins D, Rosen M. Impact of the COVID-19 pandemic on participants in pragmatic clinical trials for chronic pain: implications for trial outcomes and beyond. Pain Medicine 2024, 25: s17-s27. PMID: 39514885, PMCID: PMC11548862, DOI: 10.1093/pm/pnae060.Peer-Reviewed Original ResearchConceptsPragmatic clinical trialsHealth careSocial supportChronic painEmotional healthHigher levels of painPain Management CollaboratoryEffective pain managementClinical trialsLevel of painEffectiveness of treatment outcomesPandemic impactAlcohol use disorder screeningCOVID-19-related impactsCOVID-19 pandemicChronic pain treatmentMental healthPain managementDisorder screeningNonpharmacological treatmentsPain treatmentStudy enrollmentCOVID-19HealthCare
2023
Adherence to Antiretrovirals and HIV Viral Suppression Under COVID-19 Pandemic Interruption – Findings from a Randomized Clinical Trial Using Ingestible Sensors to Monitor Adherence
Wang Y, Daar E, Huang Y, Xiong D, Shen J, Zhou L, Siqueiros L, Guerrero M, Rosen M, Liu H. Adherence to Antiretrovirals and HIV Viral Suppression Under COVID-19 Pandemic Interruption – Findings from a Randomized Clinical Trial Using Ingestible Sensors to Monitor Adherence. AIDS And Behavior 2023, 27: 4041-4051. PMID: 37401993, PMCID: PMC10598162, DOI: 10.1007/s10461-023-04118-9.Peer-Reviewed Original ResearchConceptsLog viral loadViral loadClinical trialsHIV RNA viral loadUsual care groupHIV viral suppressionRNA viral loadRandomized clinical trialsSelf-reported adherenceLongitudinal mixed effects modelsViral suppressionClinical outcomesCare groupWeek 28Week 16Intervention groupAntiretroviralsIntervention effectsVulnerable populationsAdherenceMixed effects modelsRandom interceptRetention rateCOVID-19 pandemicIngestible sensor
2021
Optimizing the Impact of Pragmatic Clinical Trials for Veteran and Military Populations: Lessons From the Pain Management Collaboratory
Ali J, Antonelli M, Bastian L, Becker W, Brandt CA, Burgess DJ, Burns A, Cohen SP, Davis AF, Dearth CL, Dziura J, Edwards R, Erdos J, Farrokhi S, Fritz J, Geda M, George SZ, Goertz C, Goodie J, Hastings SN, Heapy A, Ilfeld BM, Katsovich L, Kerns RD, Kyriakides TC, Lee A, Long CR, Luther SL, Martino S, Matheny ME, McGeary D, Midboe A, Pasquina P, Peduzzi P, Raffanello M, Rhon D, Rosen M, Esposito ER, Scarton D, Hastings SN, Seal K, Silliker N, Taylor S, Taylor SL, Tsui M, Wright FS, Zeliadt S. Optimizing the Impact of Pragmatic Clinical Trials for Veteran and Military Populations: Lessons From the Pain Management Collaboratory. Military Medicine 2021, 187: 179-185. PMID: 34791412, PMCID: PMC9389906, DOI: 10.1093/milmed/usab458.Peer-Reviewed Original ResearchConceptsPragmatic clinical trialsPain Management CollaboratoryClinical trialsMultisite pragmatic clinical trialManagement of painDual public health crisesCommon co-occurring conditionsPragmatic trial designUnmet healthcare needsMilitary Health SystemCo-occurring conditionsPublic health crisisPain managementChronic painNonpharmacological approachesOpioid misuseMultifactorial etiologyTrial designVeterans AffairsMilitary populationHealthcare needsHealth systemNational InstitutePainCOVID-19 pandemic