2022
Using machine learning to predict heavy drinking during outpatient alcohol treatment
Roberts W, Zhao Y, Verplaetse T, Moore KE, Peltier MR, Burke C, Zakiniaeiz Y, McKee S. Using machine learning to predict heavy drinking during outpatient alcohol treatment. Alcohol Clinical And Experimental Research 2022, 46: 657-666. PMID: 35420710, PMCID: PMC9180421, DOI: 10.1111/acer.14802.Peer-Reviewed Original ResearchMeSH KeywordsAlcoholismAlgorithmsEthanolFemaleHumansMachine LearningMaleOutpatientsTreatment OutcomeConceptsAlcohol use disorderHeavy drinkingTreatment outcomesInvasive assessment methodsOutpatient AUD treatmentLast monthOutpatient alcohol treatmentMultisite clinical trialAccurate clinical predictionsHeavy alcohol useSex differencesBi-weekly sessionsAlcohol treatment outcomesPatient characteristicsClinical outcomesClinical trialsClinical dataStratified analysisEffective treatmentPsychiatric disordersUse disordersAUD treatmentSubstantial sex differencesAlcohol treatmentFirst month
2019
Pharmacokinetics and Pharmacodynamics of Immediate-Release Versus Extended-Release Guanfacine in Adult Daily Smokers.
Verplaetse TL, Roberts W, Moore KE, Peltier MR, Oberleitner LM, McKee SA. Pharmacokinetics and Pharmacodynamics of Immediate-Release Versus Extended-Release Guanfacine in Adult Daily Smokers. Journal Of Clinical Psychopharmacology 2019, 39: 124-128. PMID: 30707118, PMCID: PMC6391212, DOI: 10.1097/jcp.0000000000001004.Peer-Reviewed Original ResearchConceptsAdult daily smokersDoses of guanfacineAdverse eventsMedication levelsDaily smokersTobacco cravingTreatment-emergent adverse eventsExtended-release formulationSimilar pharmacokinetic profileAttention deficit hyperactivity disorderDry mouthLast doseMigraine prophylaxisBlood pressureHeroin withdrawalStable dosingDose equivalencyHeart rateER formulationSmoking outcomesGuanfacinePharmacokinetic profileDrug AdministrationVital signsHyperactivity disorder
2018
Motivation and Readiness for Tobacco Cessation Among Nicotine Dependent Postmenopausal Females: A Pilot Study
Peltier MR, Roys MR, Waters AF, Vinci C, Waldo KM, Stewart SA, Toups RC, Jones L, Copeland AL. Motivation and Readiness for Tobacco Cessation Among Nicotine Dependent Postmenopausal Females: A Pilot Study. Experimental And Clinical Psychopharmacology 2018, 26: 125-131. PMID: 29648860, DOI: 10.1037/pha0000191.Peer-Reviewed Original ResearchConceptsMenopausal symptom severitySymptom severityWeight concernsBrief motivational interviewingCurrent pilot studyCessation treatmentPostmenopausal femalesPostmenopausal smokersMenopausal symptomsEstrogen productionAntiestrogenic effectsConsiderable health riskB-MISomatic symptomsSmokingPilot studyMotivational interviewingBaselineSeveritySymptomsHealth risksTreatmentNegative affectCessationLow levels